EBPL

 

Full name: EBP like Alias Symbol: EBRP
Type: protein-coding gene Cytoband: 13q14.2
Entrez ID: 84650 HGNC ID: HGNC:18061 Ensembl Gene: ENSG00000123179 OMIM ID: 617335
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of EBPL:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 EBPL 84650 223306_at -0.1676 0.7106
GSE26886 EBPL 84650 223306_at -1.0447 0.0025
GSE45670 EBPL 84650 223306_at 0.0933 0.5686
GSE53622 EBPL 84650 58460 -0.7106 0.0000
GSE53624 EBPL 84650 58460 -0.3504 0.0000
GSE63941 EBPL 84650 223306_at 0.5513 0.2393
GSE77861 EBPL 84650 223306_at -0.2589 0.3237
GSE97050 EBPL 84650 A_23_P128554 -0.2856 0.3139
SRP007169 EBPL 84650 RNAseq -0.6526 0.2040
SRP008496 EBPL 84650 RNAseq -0.5337 0.0796
SRP064894 EBPL 84650 RNAseq -0.1317 0.6415
SRP133303 EBPL 84650 RNAseq -0.6016 0.0001
SRP159526 EBPL 84650 RNAseq -0.6319 0.0450
SRP193095 EBPL 84650 RNAseq -0.7537 0.0002
SRP219564 EBPL 84650 RNAseq -0.7245 0.0812
TCGA EBPL 84650 RNAseq 0.2445 0.0040

Upregulated datasets: 0; Downregulated datasets: 1.  


 

Survival by EBPL expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of EBPL:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 EBPL 84650 1 13 16
GSE20123 EBPL 84650 1 12 17
GSE43470 EBPL 84650 3 13 27
GSE46452 EBPL 84650 0 32 27
GSE47630 EBPL 84650 2 27 11
GSE54993 EBPL 84650 12 2 56
GSE54994 EBPL 84650 2 14 37
GSE60625 EBPL 84650 0 3 8
GSE74703 EBPL 84650 3 10 23
GSE74704 EBPL 84650 0 9 11
TCGA EBPL 84650 9 37 50

Total number of gains: 33; Total number of losses: 172; Total Number of normals: 283.  


 

Somatic mutations of EBPL:

 

Generating mutation plots.

 

Highly correlated genes for EBPL:

 

Showing top 20/676 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
EBPLCOG30.779584404
EBPLSUGT10.772948303
EBPLMARK20.763697303
EBPLC3orf380.761669403
EBPLLEPROT0.756261303
EBPLRABGAP1L0.755119404
EBPLARPC30.749889404
EBPLUSP6NL0.748829404
EBPLKCNK60.748612303
EBPLRNF60.746865403
EBPLHMGCS10.744818303
EBPLACAA10.741283303
EBPLMINK10.734153303
EBPLEIF3E0.728696303
EBPLHEATR5B0.727856404
EBPLTOLLIP0.722037303
EBPLHSPA40.721763303
EBPLFRMD4B0.719881404
EBPLHERC40.717625303
EBPLMRPS100.714312303

For details and further investigation, click here