| Full name: transducin beta like 2 | Alias Symbol: WS-betaTRP|WBSCR13|DKFZP43N024 | ||
| Type: protein-coding gene | Cytoband: 7q11.23 | ||
| Entrez ID: 26608 | HGNC ID: HGNC:11586 | Ensembl Gene: ENSG00000106638 | OMIM ID: 605842 |
| Drug and gene relationship at DGIdb | |||
Expression of TBL2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TBL2 | 26608 | 212685_s_at | 0.3981 | 0.2268 | |
| GSE20347 | TBL2 | 26608 | 212685_s_at | 0.4412 | 0.0113 | |
| GSE23400 | TBL2 | 26608 | 212685_s_at | 0.4996 | 0.0000 | |
| GSE26886 | TBL2 | 26608 | 212685_s_at | 0.4209 | 0.1061 | |
| GSE29001 | TBL2 | 26608 | 212685_s_at | 0.2703 | 0.2370 | |
| GSE38129 | TBL2 | 26608 | 212685_s_at | 0.5544 | 0.0000 | |
| GSE45670 | TBL2 | 26608 | 212685_s_at | 0.5794 | 0.0002 | |
| GSE53622 | TBL2 | 26608 | 12898 | 0.4979 | 0.0000 | |
| GSE53624 | TBL2 | 26608 | 12898 | 0.6191 | 0.0000 | |
| GSE63941 | TBL2 | 26608 | 212685_s_at | -0.0235 | 0.9632 | |
| GSE77861 | TBL2 | 26608 | 212685_s_at | 0.5130 | 0.0124 | |
| GSE97050 | TBL2 | 26608 | A_23_P134395 | 0.4418 | 0.1785 | |
| SRP007169 | TBL2 | 26608 | RNAseq | 0.3574 | 0.3032 | |
| SRP008496 | TBL2 | 26608 | RNAseq | 0.5706 | 0.0053 | |
| SRP064894 | TBL2 | 26608 | RNAseq | 0.6697 | 0.0002 | |
| SRP133303 | TBL2 | 26608 | RNAseq | 0.7994 | 0.0001 | |
| SRP159526 | TBL2 | 26608 | RNAseq | 0.6418 | 0.0075 | |
| SRP193095 | TBL2 | 26608 | RNAseq | 0.6705 | 0.0000 | |
| SRP219564 | TBL2 | 26608 | RNAseq | 0.6172 | 0.0217 | |
| TCGA | TBL2 | 26608 | RNAseq | 0.0960 | 0.0820 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TBL2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TBL2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TBL2 | 26608 | 14 | 1 | 15 | |
| GSE20123 | TBL2 | 26608 | 14 | 1 | 15 | |
| GSE43470 | TBL2 | 26608 | 3 | 2 | 38 | |
| GSE46452 | TBL2 | 26608 | 12 | 0 | 47 | |
| GSE47630 | TBL2 | 26608 | 7 | 2 | 31 | |
| GSE54993 | TBL2 | 26608 | 2 | 7 | 61 | |
| GSE54994 | TBL2 | 26608 | 14 | 3 | 36 | |
| GSE60625 | TBL2 | 26608 | 0 | 0 | 11 | |
| GSE74703 | TBL2 | 26608 | 3 | 1 | 32 | |
| GSE74704 | TBL2 | 26608 | 8 | 1 | 11 | |
| TCGA | TBL2 | 26608 | 45 | 7 | 44 |
Total number of gains: 122; Total number of losses: 25; Total Number of normals: 341.
Somatic mutations of TBL2:
Generating mutation plots.
Highly correlated genes for TBL2:
Showing top 20/1617 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TBL2 | RPP38 | 0.816884 | 3 | 0 | 3 |
| TBL2 | CDCA2 | 0.804142 | 4 | 0 | 4 |
| TBL2 | ANKRD16 | 0.803725 | 3 | 0 | 3 |
| TBL2 | SRPK1 | 0.770618 | 3 | 0 | 3 |
| TBL2 | L3MBTL3 | 0.765414 | 3 | 0 | 3 |
| TBL2 | MDM2 | 0.744773 | 3 | 0 | 3 |
| TBL2 | DYRK2 | 0.741587 | 3 | 0 | 3 |
| TBL2 | RNF6 | 0.732726 | 3 | 0 | 3 |
| TBL2 | DBF4 | 0.731803 | 10 | 0 | 9 |
| TBL2 | FMOD | 0.731758 | 3 | 0 | 3 |
| TBL2 | EME1 | 0.731067 | 4 | 0 | 4 |
| TBL2 | PKN1 | 0.730617 | 3 | 0 | 3 |
| TBL2 | RFC2 | 0.729888 | 10 | 0 | 10 |
| TBL2 | ZC3H18 | 0.724075 | 3 | 0 | 3 |
| TBL2 | LSM5 | 0.722147 | 9 | 0 | 9 |
| TBL2 | CLIC1 | 0.72152 | 3 | 0 | 3 |
| TBL2 | RELL1 | 0.721116 | 3 | 0 | 3 |
| TBL2 | G2E3 | 0.718946 | 5 | 0 | 4 |
| TBL2 | OSGEPL1 | 0.717577 | 3 | 0 | 3 |
| TBL2 | C1orf198 | 0.717381 | 3 | 0 | 3 |
For details and further investigation, click here
