| Full name: RNA polymerase II associated protein 2 | Alias Symbol: FLJ13150|Rtr1 | ||
| Type: protein-coding gene | Cytoband: 1p22.1 | ||
| Entrez ID: 79871 | HGNC ID: HGNC:25791 | Ensembl Gene: ENSG00000122484 | OMIM ID: 611476 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of RPAP2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RPAP2 | 79871 | 222893_s_at | 0.0728 | 0.8035 | |
| GSE20347 | RPAP2 | 79871 | 219504_s_at | -0.1192 | 0.1493 | |
| GSE23400 | RPAP2 | 79871 | 219504_s_at | -0.0625 | 0.0521 | |
| GSE26886 | RPAP2 | 79871 | 222893_s_at | 0.4345 | 0.0355 | |
| GSE29001 | RPAP2 | 79871 | 219504_s_at | -0.1373 | 0.3725 | |
| GSE38129 | RPAP2 | 79871 | 219504_s_at | -0.0846 | 0.3121 | |
| GSE45670 | RPAP2 | 79871 | 222893_s_at | 0.1012 | 0.4555 | |
| GSE53622 | RPAP2 | 79871 | 34332 | -0.0679 | 0.3840 | |
| GSE53624 | RPAP2 | 79871 | 34332 | 0.1264 | 0.0144 | |
| GSE63941 | RPAP2 | 79871 | 222893_s_at | 0.3838 | 0.5367 | |
| GSE77861 | RPAP2 | 79871 | 222893_s_at | -0.1629 | 0.2868 | |
| GSE97050 | RPAP2 | 79871 | A_23_P23542 | -0.1089 | 0.6954 | |
| SRP007169 | RPAP2 | 79871 | RNAseq | 0.5701 | 0.0865 | |
| SRP008496 | RPAP2 | 79871 | RNAseq | 0.5427 | 0.0037 | |
| SRP064894 | RPAP2 | 79871 | RNAseq | 0.0828 | 0.6499 | |
| SRP133303 | RPAP2 | 79871 | RNAseq | 0.1783 | 0.0263 | |
| SRP159526 | RPAP2 | 79871 | RNAseq | 0.0345 | 0.9043 | |
| SRP193095 | RPAP2 | 79871 | RNAseq | 0.2741 | 0.0254 | |
| SRP219564 | RPAP2 | 79871 | RNAseq | 0.0508 | 0.8978 | |
| TCGA | RPAP2 | 79871 | RNAseq | 0.1033 | 0.0870 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RPAP2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RPAP2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RPAP2 | 79871 | 0 | 8 | 22 | |
| GSE20123 | RPAP2 | 79871 | 0 | 8 | 22 | |
| GSE43470 | RPAP2 | 79871 | 2 | 6 | 35 | |
| GSE46452 | RPAP2 | 79871 | 1 | 1 | 57 | |
| GSE47630 | RPAP2 | 79871 | 8 | 5 | 27 | |
| GSE54993 | RPAP2 | 79871 | 0 | 1 | 69 | |
| GSE54994 | RPAP2 | 79871 | 6 | 3 | 44 | |
| GSE60625 | RPAP2 | 79871 | 0 | 0 | 11 | |
| GSE74703 | RPAP2 | 79871 | 1 | 5 | 30 | |
| GSE74704 | RPAP2 | 79871 | 0 | 5 | 15 | |
| TCGA | RPAP2 | 79871 | 6 | 24 | 66 |
Total number of gains: 24; Total number of losses: 66; Total Number of normals: 398.
Somatic mutations of RPAP2:
Generating mutation plots.
Highly correlated genes for RPAP2:
Showing top 20/131 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RPAP2 | RAB18 | 0.726412 | 3 | 0 | 3 |
| RPAP2 | USP40 | 0.720747 | 3 | 0 | 3 |
| RPAP2 | SON | 0.715251 | 3 | 0 | 3 |
| RPAP2 | PEX10 | 0.708159 | 3 | 0 | 3 |
| RPAP2 | SLC35A3 | 0.692756 | 5 | 0 | 5 |
| RPAP2 | FAM122C | 0.692332 | 3 | 0 | 3 |
| RPAP2 | FMO4 | 0.690997 | 3 | 0 | 3 |
| RPAP2 | STAM | 0.685276 | 3 | 0 | 3 |
| RPAP2 | ST7L | 0.681689 | 4 | 0 | 4 |
| RPAP2 | PGM1 | 0.681341 | 3 | 0 | 3 |
| RPAP2 | CHIC1 | 0.669694 | 4 | 0 | 4 |
| RPAP2 | ACBD5 | 0.668297 | 3 | 0 | 3 |
| RPAP2 | WDR20 | 0.668273 | 4 | 0 | 3 |
| RPAP2 | ATRX | 0.667283 | 3 | 0 | 3 |
| RPAP2 | TMEM184C | 0.666246 | 3 | 0 | 3 |
| RPAP2 | MED27 | 0.66613 | 4 | 0 | 3 |
| RPAP2 | CDC37L1 | 0.664733 | 3 | 0 | 3 |
| RPAP2 | BDP1 | 0.660317 | 3 | 0 | 3 |
| RPAP2 | CCNH | 0.659198 | 4 | 0 | 3 |
| RPAP2 | DNAJC27 | 0.657883 | 4 | 0 | 3 |
For details and further investigation, click here
