| Full name: peroxisomal biogenesis factor 10 | Alias Symbol: RNF69 | ||
| Type: protein-coding gene | Cytoband: 1p36.32 | ||
| Entrez ID: 5192 | HGNC ID: HGNC:8851 | Ensembl Gene: ENSG00000157911 | OMIM ID: 602859 |
| Drug and gene relationship at DGIdb | |||
Expression of PEX10:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PEX10 | 5192 | 206352_s_at | 0.1261 | 0.8216 | |
| GSE20347 | PEX10 | 5192 | 206352_s_at | 0.0077 | 0.9515 | |
| GSE23400 | PEX10 | 5192 | 206352_s_at | 0.0660 | 0.3689 | |
| GSE26886 | PEX10 | 5192 | 206352_s_at | 0.8307 | 0.0001 | |
| GSE29001 | PEX10 | 5192 | 206352_s_at | -0.1489 | 0.4687 | |
| GSE38129 | PEX10 | 5192 | 206352_s_at | 0.1358 | 0.3065 | |
| GSE45670 | PEX10 | 5192 | 206352_s_at | 0.1337 | 0.3970 | |
| GSE53622 | PEX10 | 5192 | 22915 | 0.1103 | 0.1800 | |
| GSE53624 | PEX10 | 5192 | 22915 | 0.2476 | 0.0000 | |
| GSE63941 | PEX10 | 5192 | 206352_s_at | 0.4471 | 0.0921 | |
| GSE77861 | PEX10 | 5192 | 206352_s_at | -0.1170 | 0.3587 | |
| GSE97050 | PEX10 | 5192 | A_23_P501745 | -0.0017 | 0.9962 | |
| SRP007169 | PEX10 | 5192 | RNAseq | -1.1143 | 0.0071 | |
| SRP008496 | PEX10 | 5192 | RNAseq | -0.7343 | 0.0169 | |
| SRP064894 | PEX10 | 5192 | RNAseq | 0.2999 | 0.1789 | |
| SRP133303 | PEX10 | 5192 | RNAseq | 0.2565 | 0.1870 | |
| SRP159526 | PEX10 | 5192 | RNAseq | 0.3555 | 0.2860 | |
| SRP193095 | PEX10 | 5192 | RNAseq | 0.0227 | 0.8534 | |
| SRP219564 | PEX10 | 5192 | RNAseq | 0.0125 | 0.9598 | |
| TCGA | PEX10 | 5192 | RNAseq | 0.1404 | 0.0180 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by PEX10 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PEX10:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PEX10 | 5192 | 4 | 6 | 20 | |
| GSE20123 | PEX10 | 5192 | 4 | 5 | 21 | |
| GSE43470 | PEX10 | 5192 | 3 | 5 | 35 | |
| GSE46452 | PEX10 | 5192 | 7 | 1 | 51 | |
| GSE47630 | PEX10 | 5192 | 8 | 4 | 28 | |
| GSE54993 | PEX10 | 5192 | 3 | 2 | 65 | |
| GSE54994 | PEX10 | 5192 | 15 | 2 | 36 | |
| GSE60625 | PEX10 | 5192 | 0 | 0 | 11 | |
| GSE74703 | PEX10 | 5192 | 3 | 3 | 30 | |
| GSE74704 | PEX10 | 5192 | 4 | 0 | 16 | |
| TCGA | PEX10 | 5192 | 14 | 20 | 62 |
Total number of gains: 65; Total number of losses: 48; Total Number of normals: 375.
Somatic mutations of PEX10:
Generating mutation plots.
Highly correlated genes for PEX10:
Showing top 20/290 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PEX10 | NACC1 | 0.805014 | 3 | 0 | 3 |
| PEX10 | RPS19BP1 | 0.792538 | 3 | 0 | 3 |
| PEX10 | POMGNT1 | 0.759977 | 3 | 0 | 3 |
| PEX10 | ZNF558 | 0.759642 | 3 | 0 | 3 |
| PEX10 | FBXW8 | 0.75759 | 3 | 0 | 3 |
| PEX10 | ECSIT | 0.753175 | 3 | 0 | 3 |
| PEX10 | SLC25A29 | 0.753058 | 3 | 0 | 3 |
| PEX10 | ZNF700 | 0.733043 | 3 | 0 | 3 |
| PEX10 | ZNF766 | 0.730266 | 3 | 0 | 3 |
| PEX10 | SNX15 | 0.728387 | 3 | 0 | 3 |
| PEX10 | SND1 | 0.728185 | 3 | 0 | 3 |
| PEX10 | RBM33 | 0.726764 | 3 | 0 | 3 |
| PEX10 | SRPK1 | 0.72466 | 3 | 0 | 3 |
| PEX10 | NCAPH2 | 0.721128 | 3 | 0 | 3 |
| PEX10 | GET4 | 0.719551 | 3 | 0 | 3 |
| PEX10 | SPEN | 0.719024 | 4 | 0 | 3 |
| PEX10 | NAA60 | 0.718413 | 4 | 0 | 3 |
| PEX10 | COG1 | 0.716204 | 3 | 0 | 3 |
| PEX10 | ANAPC5 | 0.714091 | 4 | 0 | 3 |
| PEX10 | BUD31 | 0.712832 | 5 | 0 | 4 |
For details and further investigation, click here
