| Full name: SON DNA binding protein | Alias Symbol: DBP-5|NREBP|KIAA1019|BASS1|FLJ21099|FLJ33914 | ||
| Type: protein-coding gene | Cytoband: 21q22.11 | ||
| Entrez ID: 6651 | HGNC ID: HGNC:11183 | Ensembl Gene: ENSG00000159140 | OMIM ID: 182465 |
| Drug and gene relationship at DGIdb | |||
Expression of SON:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SON | 6651 | 214988_s_at | 0.0100 | 0.9826 | |
| GSE20347 | SON | 6651 | 214988_s_at | -0.0803 | 0.5665 | |
| GSE23400 | SON | 6651 | 201086_x_at | 0.0610 | 0.4269 | |
| GSE26886 | SON | 6651 | 214988_s_at | 0.2340 | 0.1983 | |
| GSE29001 | SON | 6651 | 214988_s_at | -0.0084 | 0.9795 | |
| GSE38129 | SON | 6651 | 214988_s_at | -0.1324 | 0.1332 | |
| GSE45670 | SON | 6651 | 214988_s_at | -0.1521 | 0.1813 | |
| GSE53622 | SON | 6651 | 62817 | -0.1917 | 0.0001 | |
| GSE53624 | SON | 6651 | 27242 | -0.0156 | 0.7954 | |
| GSE63941 | SON | 6651 | 214988_s_at | -0.6982 | 0.0193 | |
| GSE77861 | SON | 6651 | 214988_s_at | -0.2691 | 0.2547 | |
| GSE97050 | SON | 6651 | A_33_P3421759 | -0.3182 | 0.1869 | |
| SRP007169 | SON | 6651 | RNAseq | 0.2585 | 0.5415 | |
| SRP008496 | SON | 6651 | RNAseq | 0.3058 | 0.1878 | |
| SRP064894 | SON | 6651 | RNAseq | 0.0586 | 0.6998 | |
| SRP133303 | SON | 6651 | RNAseq | -0.2981 | 0.0047 | |
| SRP159526 | SON | 6651 | RNAseq | -0.2991 | 0.0644 | |
| SRP193095 | SON | 6651 | RNAseq | -0.1575 | 0.0618 | |
| SRP219564 | SON | 6651 | RNAseq | -0.2861 | 0.2559 | |
| TCGA | SON | 6651 | RNAseq | -0.0692 | 0.0599 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SON expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SON:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SON | 6651 | 2 | 8 | 20 | |
| GSE20123 | SON | 6651 | 2 | 9 | 19 | |
| GSE43470 | SON | 6651 | 3 | 9 | 31 | |
| GSE46452 | SON | 6651 | 1 | 21 | 37 | |
| GSE47630 | SON | 6651 | 6 | 17 | 17 | |
| GSE54993 | SON | 6651 | 9 | 1 | 60 | |
| GSE54994 | SON | 6651 | 1 | 9 | 43 | |
| GSE60625 | SON | 6651 | 0 | 0 | 11 | |
| GSE74703 | SON | 6651 | 3 | 6 | 27 | |
| GSE74704 | SON | 6651 | 1 | 4 | 15 | |
| TCGA | SON | 6651 | 9 | 35 | 52 |
Total number of gains: 37; Total number of losses: 119; Total Number of normals: 332.
Somatic mutations of SON:
Generating mutation plots.
Highly correlated genes for SON:
Showing top 20/377 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SON | UXT | 0.861053 | 3 | 0 | 3 |
| SON | C1orf122 | 0.816745 | 4 | 0 | 4 |
| SON | ZNF578 | 0.815788 | 3 | 0 | 3 |
| SON | CCNY | 0.786453 | 3 | 0 | 3 |
| SON | ZNF764 | 0.778472 | 3 | 0 | 3 |
| SON | LMBRD2 | 0.766341 | 3 | 0 | 3 |
| SON | CNOT2 | 0.764577 | 3 | 0 | 3 |
| SON | CDC73 | 0.761686 | 3 | 0 | 3 |
| SON | PPM1L | 0.757672 | 3 | 0 | 3 |
| SON | IP6K1 | 0.757 | 3 | 0 | 3 |
| SON | ZNF792 | 0.751941 | 3 | 0 | 3 |
| SON | ZNF766 | 0.746358 | 3 | 0 | 3 |
| SON | COG6 | 0.743145 | 3 | 0 | 3 |
| SON | PPP2R3C | 0.743005 | 3 | 0 | 3 |
| SON | NIPAL3 | 0.735466 | 3 | 0 | 3 |
| SON | ACSS3 | 0.735015 | 3 | 0 | 3 |
| SON | MSH3 | 0.733983 | 3 | 0 | 3 |
| SON | TMCO4 | 0.731709 | 3 | 0 | 3 |
| SON | CDC23 | 0.723941 | 3 | 0 | 3 |
| SON | ZNF528 | 0.722578 | 3 | 0 | 3 |
For details and further investigation, click here
