| Full name: flavin containing dimethylaniline monoxygenase 4 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1q24.3 | ||
| Entrez ID: 2329 | HGNC ID: HGNC:3772 | Ensembl Gene: ENSG00000076258 | OMIM ID: 136131 |
| Drug and gene relationship at DGIdb | |||
Expression of FMO4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FMO4 | 2329 | 206263_at | 0.2888 | 0.3683 | |
| GSE20347 | FMO4 | 2329 | 206263_at | 0.0452 | 0.8623 | |
| GSE23400 | FMO4 | 2329 | 206263_at | -0.2161 | 0.0000 | |
| GSE26886 | FMO4 | 2329 | 206263_at | -0.2308 | 0.2618 | |
| GSE29001 | FMO4 | 2329 | 206263_at | -0.3352 | 0.0905 | |
| GSE38129 | FMO4 | 2329 | 206263_at | -0.0504 | 0.7899 | |
| GSE45670 | FMO4 | 2329 | 206263_at | 0.4846 | 0.1009 | |
| GSE63941 | FMO4 | 2329 | 206263_at | 0.4683 | 0.4000 | |
| GSE77861 | FMO4 | 2329 | 206263_at | -0.6130 | 0.0600 | |
| GSE97050 | FMO4 | 2329 | A_23_P160992 | 0.2655 | 0.3764 | |
| SRP007169 | FMO4 | 2329 | RNAseq | -0.5232 | 0.4512 | |
| SRP064894 | FMO4 | 2329 | RNAseq | 0.4356 | 0.0711 | |
| SRP133303 | FMO4 | 2329 | RNAseq | 0.7762 | 0.0238 | |
| SRP159526 | FMO4 | 2329 | RNAseq | -0.3030 | 0.3464 | |
| SRP193095 | FMO4 | 2329 | RNAseq | -0.0178 | 0.9413 | |
| SRP219564 | FMO4 | 2329 | RNAseq | 0.7977 | 0.3599 | |
| TCGA | FMO4 | 2329 | RNAseq | -0.1950 | 0.2187 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by FMO4 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of FMO4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FMO4 | 2329 | 12 | 1 | 17 | |
| GSE20123 | FMO4 | 2329 | 12 | 1 | 17 | |
| GSE43470 | FMO4 | 2329 | 7 | 2 | 34 | |
| GSE46452 | FMO4 | 2329 | 3 | 1 | 55 | |
| GSE47630 | FMO4 | 2329 | 14 | 0 | 26 | |
| GSE54993 | FMO4 | 2329 | 0 | 6 | 64 | |
| GSE54994 | FMO4 | 2329 | 16 | 0 | 37 | |
| GSE60625 | FMO4 | 2329 | 0 | 0 | 11 | |
| GSE74703 | FMO4 | 2329 | 7 | 2 | 27 | |
| GSE74704 | FMO4 | 2329 | 6 | 0 | 14 | |
| TCGA | FMO4 | 2329 | 43 | 3 | 50 |
Total number of gains: 120; Total number of losses: 16; Total Number of normals: 352.
Somatic mutations of FMO4:
Generating mutation plots.
Highly correlated genes for FMO4:
Showing top 20/177 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FMO4 | TMEM214 | 0.774113 | 3 | 0 | 3 |
| FMO4 | MRPS18C | 0.737664 | 3 | 0 | 3 |
| FMO4 | C2CD2 | 0.729658 | 4 | 0 | 4 |
| FMO4 | TMEM219 | 0.712234 | 3 | 0 | 3 |
| FMO4 | CCDC7 | 0.710413 | 4 | 0 | 4 |
| FMO4 | SFT2D3 | 0.710041 | 3 | 0 | 3 |
| FMO4 | SCAF1 | 0.708561 | 3 | 0 | 3 |
| FMO4 | FMO3 | 0.707704 | 3 | 0 | 3 |
| FMO4 | KDM5C | 0.706204 | 3 | 0 | 3 |
| FMO4 | ZMAT1 | 0.706116 | 3 | 0 | 3 |
| FMO4 | PRADC1 | 0.700679 | 3 | 0 | 3 |
| FMO4 | TMEM165 | 0.694823 | 3 | 0 | 3 |
| FMO4 | TATDN2 | 0.694551 | 3 | 0 | 3 |
| FMO4 | RPAP2 | 0.690997 | 3 | 0 | 3 |
| FMO4 | AKR7A2 | 0.690659 | 3 | 0 | 3 |
| FMO4 | RTN4R | 0.688828 | 3 | 0 | 3 |
| FMO4 | WDR77 | 0.688572 | 3 | 0 | 3 |
| FMO4 | PCNT | 0.675972 | 4 | 0 | 3 |
| FMO4 | FPGT | 0.674304 | 4 | 0 | 4 |
| FMO4 | PRDM5 | 0.673782 | 3 | 0 | 3 |
For details and further investigation, click here
