| Full name: ubiquitin A-52 residue ribosomal protein fusion product 1 | Alias Symbol: RPL40|CEP52|HUBCEP52|MGC57125|MGC126879|MGC126881|L40 | ||
| Type: protein-coding gene | Cytoband: 19p13.1-p12 | ||
| Entrez ID: 7311 | HGNC ID: HGNC:12458 | Ensembl Gene: ENSG00000221983 | OMIM ID: 191321 |
| Drug and gene relationship at DGIdb | |||
Expression of UBA52:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | UBA52 | 7311 | 221700_s_at | 0.0011 | 0.9982 | |
| GSE20347 | UBA52 | 7311 | 221700_s_at | -0.2220 | 0.0150 | |
| GSE23400 | UBA52 | 7311 | 221700_s_at | -0.0477 | 0.4247 | |
| GSE26886 | UBA52 | 7311 | 221700_s_at | 0.5402 | 0.0000 | |
| GSE29001 | UBA52 | 7311 | 221700_s_at | -0.1539 | 0.5213 | |
| GSE38129 | UBA52 | 7311 | 221700_s_at | -0.0340 | 0.6966 | |
| GSE45670 | UBA52 | 7311 | 221700_s_at | -0.1368 | 0.0963 | |
| GSE53622 | UBA52 | 7311 | 6081 | -0.1714 | 0.0025 | |
| GSE53624 | UBA52 | 7311 | 6081 | 0.0284 | 0.5917 | |
| GSE63941 | UBA52 | 7311 | 221700_s_at | 0.2748 | 0.1559 | |
| GSE77861 | UBA52 | 7311 | 221700_s_at | -0.1540 | 0.3702 | |
| GSE97050 | UBA52 | 7311 | A_24_P173325 | 0.0402 | 0.8800 | |
| SRP007169 | UBA52 | 7311 | RNAseq | -0.6864 | 0.0288 | |
| SRP008496 | UBA52 | 7311 | RNAseq | -0.8546 | 0.0001 | |
| SRP064894 | UBA52 | 7311 | RNAseq | 0.0190 | 0.9608 | |
| SRP133303 | UBA52 | 7311 | RNAseq | -0.4175 | 0.0023 | |
| SRP159526 | UBA52 | 7311 | RNAseq | -0.5759 | 0.0008 | |
| SRP193095 | UBA52 | 7311 | RNAseq | -0.6784 | 0.0000 | |
| SRP219564 | UBA52 | 7311 | RNAseq | -0.0584 | 0.8287 | |
| TCGA | UBA52 | 7311 | RNAseq | 0.0577 | 0.2291 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by UBA52 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of UBA52:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | UBA52 | 7311 | 4 | 5 | 21 | |
| GSE20123 | UBA52 | 7311 | 3 | 3 | 24 | |
| GSE43470 | UBA52 | 7311 | 2 | 5 | 36 | |
| GSE46452 | UBA52 | 7311 | 47 | 1 | 11 | |
| GSE47630 | UBA52 | 7311 | 4 | 8 | 28 | |
| GSE54993 | UBA52 | 7311 | 15 | 4 | 51 | |
| GSE54994 | UBA52 | 7311 | 6 | 13 | 34 | |
| GSE60625 | UBA52 | 7311 | 9 | 0 | 2 | |
| GSE74703 | UBA52 | 7311 | 2 | 3 | 31 | |
| GSE74704 | UBA52 | 7311 | 0 | 3 | 17 | |
| TCGA | UBA52 | 7311 | 16 | 10 | 70 |
Total number of gains: 108; Total number of losses: 55; Total Number of normals: 325.
Somatic mutations of UBA52:
Generating mutation plots.
Highly correlated genes for UBA52:
Showing top 20/329 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| UBA52 | ANAPC5 | 0.798975 | 3 | 0 | 3 |
| UBA52 | POP5 | 0.790853 | 3 | 0 | 3 |
| UBA52 | KBTBD4 | 0.786445 | 3 | 0 | 3 |
| UBA52 | WDR25 | 0.782194 | 4 | 0 | 4 |
| UBA52 | ZNF616 | 0.77889 | 3 | 0 | 3 |
| UBA52 | MRPL20 | 0.774672 | 3 | 0 | 3 |
| UBA52 | ZNF318 | 0.771984 | 3 | 0 | 3 |
| UBA52 | NACC1 | 0.765561 | 3 | 0 | 3 |
| UBA52 | PRELID1 | 0.758567 | 3 | 0 | 3 |
| UBA52 | MEA1 | 0.757256 | 4 | 0 | 4 |
| UBA52 | CASKIN2 | 0.756682 | 3 | 0 | 3 |
| UBA52 | TEAD2 | 0.743752 | 3 | 0 | 3 |
| UBA52 | CRTC2 | 0.742981 | 3 | 0 | 3 |
| UBA52 | HSPB11 | 0.739851 | 3 | 0 | 3 |
| UBA52 | ZNF41 | 0.738502 | 3 | 0 | 3 |
| UBA52 | MRPS18A | 0.737776 | 4 | 0 | 4 |
| UBA52 | ACAD9 | 0.73669 | 3 | 0 | 3 |
| UBA52 | SLC25A19 | 0.731405 | 3 | 0 | 3 |
| UBA52 | HIC2 | 0.727622 | 4 | 0 | 3 |
| UBA52 | AIMP2 | 0.724662 | 3 | 0 | 3 |
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