| Full name: ribosomal protein S16 | Alias Symbol: S16 | ||
| Type: protein-coding gene | Cytoband: 19q13.1 | ||
| Entrez ID: 6217 | HGNC ID: HGNC:10396 | Ensembl Gene: ENSG00000105193 | OMIM ID: 603675 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of RPS16:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RPS16 | 6217 | 226131_s_at | -0.0150 | 0.9469 | |
| GSE20347 | RPS16 | 6217 | 213890_x_at | 0.0637 | 0.4839 | |
| GSE23400 | RPS16 | 6217 | 213890_x_at | 0.1294 | 0.0448 | |
| GSE26886 | RPS16 | 6217 | 226131_s_at | -0.0409 | 0.7136 | |
| GSE29001 | RPS16 | 6217 | 213890_x_at | 0.0208 | 0.9162 | |
| GSE38129 | RPS16 | 6217 | 213890_x_at | 0.0700 | 0.2795 | |
| GSE45670 | RPS16 | 6217 | 226131_s_at | -0.0670 | 0.2227 | |
| GSE53622 | RPS16 | 6217 | 138645 | -0.3851 | 0.0000 | |
| GSE53624 | RPS16 | 6217 | 138645 | 0.0053 | 0.9341 | |
| GSE63941 | RPS16 | 6217 | 226131_s_at | 0.1194 | 0.3344 | |
| GSE77861 | RPS16 | 6217 | 226131_s_at | 0.0527 | 0.6337 | |
| GSE97050 | RPS16 | 6217 | A_23_P208850 | -0.2082 | 0.4257 | |
| SRP007169 | RPS16 | 6217 | RNAseq | -0.6456 | 0.1190 | |
| SRP008496 | RPS16 | 6217 | RNAseq | -0.8167 | 0.0006 | |
| SRP064894 | RPS16 | 6217 | RNAseq | -0.0926 | 0.7875 | |
| SRP133303 | RPS16 | 6217 | RNAseq | -0.2256 | 0.1980 | |
| SRP159526 | RPS16 | 6217 | RNAseq | -0.3856 | 0.0119 | |
| SRP193095 | RPS16 | 6217 | RNAseq | -1.1132 | 0.0009 | |
| SRP219564 | RPS16 | 6217 | RNAseq | -0.2013 | 0.5368 | |
| TCGA | RPS16 | 6217 | RNAseq | 0.0591 | 0.2438 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by RPS16 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RPS16:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RPS16 | 6217 | 7 | 4 | 19 | |
| GSE20123 | RPS16 | 6217 | 7 | 3 | 20 | |
| GSE43470 | RPS16 | 6217 | 3 | 11 | 29 | |
| GSE46452 | RPS16 | 6217 | 48 | 1 | 10 | |
| GSE47630 | RPS16 | 6217 | 9 | 5 | 26 | |
| GSE54993 | RPS16 | 6217 | 17 | 3 | 50 | |
| GSE54994 | RPS16 | 6217 | 7 | 9 | 37 | |
| GSE60625 | RPS16 | 6217 | 9 | 0 | 2 | |
| GSE74703 | RPS16 | 6217 | 3 | 7 | 26 | |
| GSE74704 | RPS16 | 6217 | 7 | 1 | 12 | |
| TCGA | RPS16 | 6217 | 14 | 16 | 66 |
Total number of gains: 131; Total number of losses: 60; Total Number of normals: 297.
Somatic mutations of RPS16:
Generating mutation plots.
Highly correlated genes for RPS16:
Showing top 20/155 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RPS16 | HLA-DPA1 | 0.718586 | 3 | 0 | 3 |
| RPS16 | KDM4B | 0.716793 | 3 | 0 | 3 |
| RPS16 | RPL13A | 0.713236 | 3 | 0 | 3 |
| RPS16 | POLR3GL | 0.70922 | 3 | 0 | 3 |
| RPS16 | RPL18A | 0.70851 | 3 | 0 | 3 |
| RPS16 | PRRC2C | 0.70823 | 3 | 0 | 3 |
| RPS16 | NCOA4 | 0.707256 | 3 | 0 | 3 |
| RPS16 | MORF4L1 | 0.698423 | 4 | 0 | 4 |
| RPS16 | LAPTM4A | 0.69717 | 3 | 0 | 3 |
| RPS16 | LAP3 | 0.694821 | 3 | 0 | 3 |
| RPS16 | ATP11C | 0.691986 | 3 | 0 | 3 |
| RPS16 | LSM6 | 0.691134 | 3 | 0 | 3 |
| RPS16 | FYN | 0.691109 | 3 | 0 | 3 |
| RPS16 | EIF4EBP2 | 0.679862 | 3 | 0 | 3 |
| RPS16 | SRI | 0.673683 | 3 | 0 | 3 |
| RPS16 | RHOBTB3 | 0.665646 | 3 | 0 | 3 |
| RPS16 | ZFHX3 | 0.661793 | 3 | 0 | 3 |
| RPS16 | OSR2 | 0.657515 | 3 | 0 | 3 |
| RPS16 | HMGB2 | 0.656134 | 3 | 0 | 3 |
| RPS16 | FBL | 0.652505 | 13 | 0 | 11 |
For details and further investigation, click here
