| Full name: ubiquitin specific peptidase 30 | Alias Symbol: MGC10702|FLJ40511 | ||
| Type: protein-coding gene | Cytoband: 12q24.11 | ||
| Entrez ID: 84749 | HGNC ID: HGNC:20065 | Ensembl Gene: ENSG00000135093 | OMIM ID: 612492 |
| Drug and gene relationship at DGIdb | |||
Expression of USP30:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | USP30 | 84749 | 223602_at | -0.1485 | 0.8170 | |
| GSE26886 | USP30 | 84749 | 223602_at | 0.1387 | 0.5793 | |
| GSE45670 | USP30 | 84749 | 227572_at | -0.7344 | 0.0000 | |
| GSE53622 | USP30 | 84749 | 20436 | -0.1071 | 0.1186 | |
| GSE53624 | USP30 | 84749 | 20436 | -0.0120 | 0.8441 | |
| GSE63941 | USP30 | 84749 | 223602_at | 1.0407 | 0.0009 | |
| GSE77861 | USP30 | 84749 | 227572_at | -0.3014 | 0.1747 | |
| GSE97050 | USP30 | 84749 | A_24_P87114 | -0.0427 | 0.8914 | |
| SRP007169 | USP30 | 84749 | RNAseq | -0.2252 | 0.5736 | |
| SRP008496 | USP30 | 84749 | RNAseq | -0.1629 | 0.6068 | |
| SRP064894 | USP30 | 84749 | RNAseq | -0.3947 | 0.0097 | |
| SRP133303 | USP30 | 84749 | RNAseq | -0.2459 | 0.2258 | |
| SRP159526 | USP30 | 84749 | RNAseq | 0.1580 | 0.5785 | |
| SRP193095 | USP30 | 84749 | RNAseq | -0.2970 | 0.0002 | |
| SRP219564 | USP30 | 84749 | RNAseq | -0.0968 | 0.6949 | |
| TCGA | USP30 | 84749 | RNAseq | -0.1273 | 0.0324 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by USP30 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of USP30:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | USP30 | 84749 | 5 | 3 | 22 | |
| GSE20123 | USP30 | 84749 | 5 | 4 | 21 | |
| GSE43470 | USP30 | 84749 | 2 | 1 | 40 | |
| GSE46452 | USP30 | 84749 | 9 | 1 | 49 | |
| GSE47630 | USP30 | 84749 | 9 | 1 | 30 | |
| GSE54993 | USP30 | 84749 | 0 | 5 | 65 | |
| GSE54994 | USP30 | 84749 | 3 | 3 | 47 | |
| GSE60625 | USP30 | 84749 | 0 | 0 | 11 | |
| GSE74703 | USP30 | 84749 | 2 | 0 | 34 | |
| GSE74704 | USP30 | 84749 | 2 | 2 | 16 | |
| TCGA | USP30 | 84749 | 21 | 10 | 65 |
Total number of gains: 58; Total number of losses: 30; Total Number of normals: 400.
Somatic mutations of USP30:
Generating mutation plots.
Highly correlated genes for USP30:
Showing top 20/93 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| USP30 | MGAT4A | 0.69929 | 3 | 0 | 3 |
| USP30 | CAMSAP1 | 0.696736 | 3 | 0 | 3 |
| USP30 | MYO5B | 0.673865 | 3 | 0 | 3 |
| USP30 | ACVR1B | 0.668965 | 3 | 0 | 3 |
| USP30 | ELMO2 | 0.663917 | 3 | 0 | 3 |
| USP30 | TMEM186 | 0.647701 | 3 | 0 | 3 |
| USP30 | WWOX | 0.63797 | 3 | 0 | 3 |
| USP30 | MAP7 | 0.636915 | 3 | 0 | 3 |
| USP30 | APPL1 | 0.633235 | 4 | 0 | 3 |
| USP30 | ETFDH | 0.630223 | 4 | 0 | 4 |
| USP30 | MUC15 | 0.628874 | 3 | 0 | 3 |
| USP30 | USP38 | 0.626468 | 3 | 0 | 3 |
| USP30 | ESRP1 | 0.6259 | 3 | 0 | 3 |
| USP30 | MTERF4 | 0.623962 | 3 | 0 | 3 |
| USP30 | CYP4F12 | 0.617251 | 4 | 0 | 4 |
| USP30 | COPZ1 | 0.611392 | 3 | 0 | 3 |
| USP30 | FAM3B | 0.610945 | 3 | 0 | 3 |
| USP30 | CTSG | 0.610414 | 3 | 0 | 3 |
| USP30 | BARX2 | 0.610078 | 3 | 0 | 3 |
| USP30 | NAPA | 0.606223 | 3 | 0 | 3 |
For details and further investigation, click here
