| Full name: cytochrome c oxidase subunit 7A2 | Alias Symbol: COXVIIa-L|COX7AL | ||
| Type: protein-coding gene | Cytoband: 6q14.1 | ||
| Entrez ID: 1347 | HGNC ID: HGNC:2288 | Ensembl Gene: ENSG00000112695 | OMIM ID: 123996 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of COX7A2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | COX7A2 | 1347 | 201597_at | -0.0983 | 0.7000 | |
| GSE20347 | COX7A2 | 1347 | 201597_at | -0.0964 | 0.1542 | |
| GSE23400 | COX7A2 | 1347 | 201597_at | -0.1053 | 0.1468 | |
| GSE26886 | COX7A2 | 1347 | 201597_at | -0.2454 | 0.0486 | |
| GSE29001 | COX7A2 | 1347 | 201597_at | -0.2528 | 0.3079 | |
| GSE38129 | COX7A2 | 1347 | 201597_at | -0.1346 | 0.0874 | |
| GSE45670 | COX7A2 | 1347 | 201597_at | -0.0009 | 0.9947 | |
| GSE53622 | COX7A2 | 1347 | 3331 | -0.6763 | 0.0000 | |
| GSE53624 | COX7A2 | 1347 | 3331 | -0.2594 | 0.0000 | |
| GSE63941 | COX7A2 | 1347 | 201597_at | 0.4624 | 0.1432 | |
| GSE77861 | COX7A2 | 1347 | 201597_at | -0.2614 | 0.4321 | |
| GSE97050 | COX7A2 | 1347 | A_23_P81690 | -0.5296 | 0.1215 | |
| SRP007169 | COX7A2 | 1347 | RNAseq | -1.1352 | 0.0002 | |
| SRP008496 | COX7A2 | 1347 | RNAseq | -1.2833 | 0.0000 | |
| SRP064894 | COX7A2 | 1347 | RNAseq | -0.5776 | 0.0262 | |
| SRP133303 | COX7A2 | 1347 | RNAseq | -0.2201 | 0.1175 | |
| SRP159526 | COX7A2 | 1347 | RNAseq | -0.7202 | 0.0030 | |
| SRP193095 | COX7A2 | 1347 | RNAseq | -1.2167 | 0.0000 | |
| SRP219564 | COX7A2 | 1347 | RNAseq | -0.8652 | 0.0000 | |
| TCGA | COX7A2 | 1347 | RNAseq | -0.1723 | 0.0006 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by COX7A2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of COX7A2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | COX7A2 | 1347 | 1 | 3 | 26 | |
| GSE20123 | COX7A2 | 1347 | 1 | 2 | 27 | |
| GSE43470 | COX7A2 | 1347 | 3 | 0 | 40 | |
| GSE46452 | COX7A2 | 1347 | 2 | 11 | 46 | |
| GSE47630 | COX7A2 | 1347 | 8 | 4 | 28 | |
| GSE54993 | COX7A2 | 1347 | 3 | 2 | 65 | |
| GSE54994 | COX7A2 | 1347 | 8 | 6 | 39 | |
| GSE60625 | COX7A2 | 1347 | 0 | 1 | 10 | |
| GSE74703 | COX7A2 | 1347 | 3 | 0 | 33 | |
| GSE74704 | COX7A2 | 1347 | 0 | 1 | 19 | |
| TCGA | COX7A2 | 1347 | 9 | 20 | 67 |
Total number of gains: 38; Total number of losses: 50; Total Number of normals: 400.
Somatic mutations of COX7A2:
Generating mutation plots.
Highly correlated genes for COX7A2:
Showing top 20/334 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| COX7A2 | PPP1R8 | 0.692232 | 3 | 0 | 3 |
| COX7A2 | ABR | 0.67255 | 3 | 0 | 3 |
| COX7A2 | DUSP22 | 0.651472 | 3 | 0 | 3 |
| COX7A2 | SSBP1 | 0.649606 | 3 | 0 | 3 |
| COX7A2 | COX5A | 0.646976 | 8 | 0 | 6 |
| COX7A2 | PRDX4 | 0.645528 | 4 | 0 | 4 |
| COX7A2 | XK | 0.642967 | 4 | 0 | 3 |
| COX7A2 | TAF7 | 0.63566 | 3 | 0 | 3 |
| COX7A2 | ATE1 | 0.635028 | 4 | 0 | 3 |
| COX7A2 | RPS13 | 0.632617 | 3 | 0 | 3 |
| COX7A2 | SLITRK3 | 0.623922 | 3 | 0 | 3 |
| COX7A2 | SDHB | 0.617004 | 5 | 0 | 4 |
| COX7A2 | KIF9 | 0.615281 | 3 | 0 | 3 |
| COX7A2 | TXNL1 | 0.615032 | 6 | 0 | 5 |
| COX7A2 | ATP1B1 | 0.614815 | 4 | 0 | 3 |
| COX7A2 | MYL6 | 0.613372 | 5 | 0 | 4 |
| COX7A2 | NACA | 0.612267 | 6 | 0 | 4 |
| COX7A2 | FAM200B | 0.611237 | 3 | 0 | 3 |
| COX7A2 | KLF4 | 0.610862 | 4 | 0 | 4 |
| COX7A2 | DPP8 | 0.608562 | 4 | 0 | 3 |
For details and further investigation, click here
