| Full name: NHP2 ribonucleoprotein | Alias Symbol: FLJ20479 | ||
| Type: protein-coding gene | Cytoband: 5q35.3 | ||
| Entrez ID: 55651 | HGNC ID: HGNC:14377 | Ensembl Gene: ENSG00000145912 | OMIM ID: 606470 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of NHP2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NHP2 | 55651 | 209104_s_at | -0.1462 | 0.8266 | |
| GSE20347 | NHP2 | 55651 | 209104_s_at | -0.5986 | 0.0024 | |
| GSE23400 | NHP2 | 55651 | 209104_s_at | -0.2930 | 0.0003 | |
| GSE26886 | NHP2 | 55651 | 209104_s_at | -1.2053 | 0.0000 | |
| GSE29001 | NHP2 | 55651 | 209104_s_at | -0.5925 | 0.2462 | |
| GSE38129 | NHP2 | 55651 | 209104_s_at | -0.2507 | 0.1394 | |
| GSE45670 | NHP2 | 55651 | 209104_s_at | -0.2675 | 0.0611 | |
| GSE63941 | NHP2 | 55651 | 209104_s_at | 0.6233 | 0.1772 | |
| GSE77861 | NHP2 | 55651 | 209104_s_at | -0.5372 | 0.0268 | |
| GSE97050 | NHP2 | 55651 | A_33_P3389942 | -0.1885 | 0.3207 | |
| SRP007169 | NHP2 | 55651 | RNAseq | -1.8861 | 0.0000 | |
| SRP008496 | NHP2 | 55651 | RNAseq | -2.0507 | 0.0000 | |
| SRP064894 | NHP2 | 55651 | RNAseq | -0.3026 | 0.3163 | |
| SRP133303 | NHP2 | 55651 | RNAseq | -0.4757 | 0.0094 | |
| SRP159526 | NHP2 | 55651 | RNAseq | -0.6423 | 0.0508 | |
| SRP193095 | NHP2 | 55651 | RNAseq | -0.7445 | 0.0000 | |
| SRP219564 | NHP2 | 55651 | RNAseq | -0.2637 | 0.4786 | |
| TCGA | NHP2 | 55651 | RNAseq | 0.1363 | 0.0365 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by NHP2 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of NHP2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NHP2 | 55651 | 2 | 13 | 15 | |
| GSE20123 | NHP2 | 55651 | 2 | 13 | 15 | |
| GSE43470 | NHP2 | 55651 | 1 | 11 | 31 | |
| GSE46452 | NHP2 | 55651 | 0 | 27 | 32 | |
| GSE47630 | NHP2 | 55651 | 1 | 20 | 19 | |
| GSE54993 | NHP2 | 55651 | 10 | 2 | 58 | |
| GSE54994 | NHP2 | 55651 | 2 | 17 | 34 | |
| GSE60625 | NHP2 | 55651 | 1 | 0 | 10 | |
| GSE74703 | NHP2 | 55651 | 1 | 7 | 28 | |
| GSE74704 | NHP2 | 55651 | 1 | 6 | 13 | |
| TCGA | NHP2 | 55651 | 8 | 34 | 54 |
Total number of gains: 29; Total number of losses: 150; Total Number of normals: 309.
Somatic mutations of NHP2:
Generating mutation plots.
Highly correlated genes for NHP2:
Showing top 20/441 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NHP2 | TPRN | 0.765803 | 3 | 0 | 3 |
| NHP2 | RCAN3 | 0.719036 | 5 | 0 | 4 |
| NHP2 | VSIG10L | 0.714798 | 4 | 0 | 3 |
| NHP2 | TMEM120A | 0.699442 | 3 | 0 | 3 |
| NHP2 | ATP12A | 0.695623 | 3 | 0 | 3 |
| NHP2 | MIEF2 | 0.686035 | 3 | 0 | 3 |
| NHP2 | BCAS1 | 0.682464 | 4 | 0 | 4 |
| NHP2 | AGAP3 | 0.677891 | 3 | 0 | 3 |
| NHP2 | LMAN2 | 0.676576 | 10 | 0 | 8 |
| NHP2 | TMEM125 | 0.673433 | 5 | 0 | 4 |
| NHP2 | CNFN | 0.673029 | 4 | 0 | 4 |
| NHP2 | ST3GAL3 | 0.672628 | 3 | 0 | 3 |
| NHP2 | SCGB1A1 | 0.670881 | 4 | 0 | 4 |
| NHP2 | BCO2 | 0.668942 | 3 | 0 | 3 |
| NHP2 | FAAH2 | 0.66257 | 3 | 0 | 3 |
| NHP2 | SMPD2 | 0.662027 | 7 | 0 | 7 |
| NHP2 | APOM | 0.661377 | 4 | 0 | 3 |
| NHP2 | RAB11FIP1 | 0.661084 | 4 | 0 | 3 |
| NHP2 | GPR78 | 0.658786 | 3 | 0 | 3 |
| NHP2 | ATP6V1F | 0.657923 | 9 | 0 | 8 |
For details and further investigation, click here
