| Full name: ribosomal protein lateral stalk subunit P1 | Alias Symbol: LP1 | ||
| Type: protein-coding gene | Cytoband: 15q23 | ||
| Entrez ID: 6176 | HGNC ID: HGNC:10372 | Ensembl Gene: ENSG00000137818 | OMIM ID: 180520 |
| Drug and gene relationship at DGIdb | |||
Expression of RPLP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RPLP1 | 6176 | 200763_s_at | -0.0531 | 0.8114 | |
| GSE20347 | RPLP1 | 6176 | 200763_s_at | 0.0958 | 0.1808 | |
| GSE23400 | RPLP1 | 6176 | 200763_s_at | -0.0212 | 0.7039 | |
| GSE26886 | RPLP1 | 6176 | 200763_s_at | 0.0567 | 0.6430 | |
| GSE29001 | RPLP1 | 6176 | 200763_s_at | -0.2592 | 0.3904 | |
| GSE38129 | RPLP1 | 6176 | 200763_s_at | 0.1273 | 0.0214 | |
| GSE45670 | RPLP1 | 6176 | 200763_s_at | -0.1481 | 0.0364 | |
| GSE63941 | RPLP1 | 6176 | 200763_s_at | 0.0592 | 0.6974 | |
| GSE77861 | RPLP1 | 6176 | 200763_s_at | -0.0505 | 0.7695 | |
| GSE97050 | RPLP1 | 6176 | A_32_P857658 | -0.7694 | 0.1563 | |
| SRP007169 | RPLP1 | 6176 | RNAseq | -1.5615 | 0.0001 | |
| SRP008496 | RPLP1 | 6176 | RNAseq | -1.3384 | 0.0000 | |
| SRP064894 | RPLP1 | 6176 | RNAseq | -0.0238 | 0.9564 | |
| SRP133303 | RPLP1 | 6176 | RNAseq | -0.5361 | 0.0007 | |
| SRP159526 | RPLP1 | 6176 | RNAseq | -0.5991 | 0.0526 | |
| SRP193095 | RPLP1 | 6176 | RNAseq | -0.9032 | 0.0000 | |
| SRP219564 | RPLP1 | 6176 | RNAseq | 0.0129 | 0.9762 | |
| TCGA | RPLP1 | 6176 | RNAseq | 0.0112 | 0.7922 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by RPLP1 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of RPLP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RPLP1 | 6176 | 7 | 1 | 22 | |
| GSE20123 | RPLP1 | 6176 | 7 | 1 | 22 | |
| GSE43470 | RPLP1 | 6176 | 4 | 6 | 33 | |
| GSE46452 | RPLP1 | 6176 | 3 | 7 | 49 | |
| GSE47630 | RPLP1 | 6176 | 8 | 10 | 22 | |
| GSE54993 | RPLP1 | 6176 | 5 | 6 | 59 | |
| GSE54994 | RPLP1 | 6176 | 5 | 7 | 41 | |
| GSE60625 | RPLP1 | 6176 | 4 | 0 | 7 | |
| GSE74703 | RPLP1 | 6176 | 4 | 3 | 29 | |
| GSE74704 | RPLP1 | 6176 | 3 | 1 | 16 | |
| TCGA | RPLP1 | 6176 | 10 | 15 | 71 |
Total number of gains: 60; Total number of losses: 57; Total Number of normals: 371.
Somatic mutations of RPLP1:
Generating mutation plots.
Highly correlated genes for RPLP1:
Showing top 20/70 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RPLP1 | RPLP0 | 0.653868 | 9 | 0 | 7 |
| RPLP1 | RPS17 | 0.653729 | 8 | 0 | 7 |
| RPLP1 | NEO1 | 0.652483 | 3 | 0 | 3 |
| RPLP1 | RPS28 | 0.647841 | 6 | 0 | 5 |
| RPLP1 | RPS4X | 0.638298 | 6 | 0 | 5 |
| RPLP1 | EEF1A1 | 0.638148 | 6 | 0 | 5 |
| RPLP1 | EPB41L4A-AS1 | 0.632506 | 3 | 0 | 3 |
| RPLP1 | RPL32 | 0.630445 | 4 | 0 | 4 |
| RPLP1 | RPL3 | 0.616394 | 6 | 0 | 4 |
| RPLP1 | EEF2 | 0.613453 | 4 | 0 | 4 |
| RPLP1 | DANCR | 0.611022 | 4 | 0 | 3 |
| RPLP1 | RPS18 | 0.610748 | 8 | 0 | 4 |
| RPLP1 | RPL12 | 0.61029 | 6 | 0 | 5 |
| RPLP1 | RPS3 | 0.609723 | 4 | 0 | 3 |
| RPLP1 | RPL6 | 0.608831 | 6 | 0 | 4 |
| RPLP1 | RPS6 | 0.60555 | 7 | 0 | 5 |
| RPLP1 | RPL39 | 0.596426 | 6 | 0 | 4 |
| RPLP1 | RPL18 | 0.594758 | 7 | 0 | 5 |
| RPLP1 | RPL34 | 0.592145 | 4 | 0 | 3 |
| RPLP1 | FAM98C | 0.587903 | 4 | 0 | 3 |
For details and further investigation, click here
