| Full name: ribosomal protein L6 | Alias Symbol: TAXREB107|L6 | ||
| Type: protein-coding gene | Cytoband: 12q24.13 | ||
| Entrez ID: 6128 | HGNC ID: HGNC:10362 | Ensembl Gene: | OMIM ID: 603703 |
| Drug and gene relationship at DGIdb | |||
Expression of RPL6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RPL6 | 6128 | 200034_s_at | -0.0662 | 0.7760 | |
| GSE20347 | RPL6 | 6128 | 200034_s_at | -0.2043 | 0.0671 | |
| GSE23400 | RPL6 | 6128 | 200034_s_at | -0.0894 | 0.1987 | |
| GSE26886 | RPL6 | 6128 | 200034_s_at | -0.2774 | 0.0903 | |
| GSE29001 | RPL6 | 6128 | 200034_s_at | -0.4063 | 0.2877 | |
| GSE38129 | RPL6 | 6128 | 200034_s_at | -0.1752 | 0.0288 | |
| GSE45670 | RPL6 | 6128 | 200034_s_at | -0.1810 | 0.0088 | |
| GSE53622 | RPL6 | 6128 | 81399 | -0.0072 | 0.9148 | |
| GSE53624 | RPL6 | 6128 | 81399 | 0.0110 | 0.8551 | |
| GSE63941 | RPL6 | 6128 | 200034_s_at | 0.7070 | 0.0000 | |
| GSE77861 | RPL6 | 6128 | 200034_s_at | -0.2076 | 0.1768 | |
| GSE97050 | RPL6 | 6128 | A_23_P151321 | -0.3998 | 0.1996 | |
| SRP007169 | RPL6 | 6128 | RNAseq | -1.0199 | 0.0029 | |
| SRP008496 | RPL6 | 6128 | RNAseq | -0.8928 | 0.0001 | |
| SRP064894 | RPL6 | 6128 | RNAseq | -0.5158 | 0.0453 | |
| SRP133303 | RPL6 | 6128 | RNAseq | -0.5484 | 0.0000 | |
| SRP159526 | RPL6 | 6128 | RNAseq | -0.5637 | 0.0001 | |
| SRP193095 | RPL6 | 6128 | RNAseq | -0.9552 | 0.0000 | |
| SRP219564 | RPL6 | 6128 | RNAseq | -0.7921 | 0.0169 | |
| TCGA | RPL6 | 6128 | RNAseq | 0.0079 | 0.8677 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by RPL6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RPL6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RPL6 | 6128 | 4 | 3 | 23 | |
| GSE20123 | RPL6 | 6128 | 4 | 3 | 23 | |
| GSE43470 | RPL6 | 6128 | 2 | 1 | 40 | |
| GSE46452 | RPL6 | 6128 | 9 | 1 | 49 | |
| GSE47630 | RPL6 | 6128 | 9 | 3 | 28 | |
| GSE54993 | RPL6 | 6128 | 0 | 5 | 65 | |
| GSE54994 | RPL6 | 6128 | 4 | 2 | 47 | |
| GSE60625 | RPL6 | 6128 | 0 | 0 | 11 | |
| GSE74703 | RPL6 | 6128 | 2 | 0 | 34 | |
| GSE74704 | RPL6 | 6128 | 2 | 2 | 16 | |
| TCGA | RPL6 | 6128 | 22 | 11 | 63 |
Total number of gains: 58; Total number of losses: 31; Total Number of normals: 399.
Somatic mutations of RPL6:
Generating mutation plots.
Highly correlated genes for RPL6:
Showing top 20/224 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RPL6 | NACA | 0.712989 | 11 | 0 | 11 |
| RPL6 | PEX2 | 0.696634 | 4 | 0 | 4 |
| RPL6 | RPLP0 | 0.692891 | 11 | 0 | 10 |
| RPL6 | TMEM50A | 0.670027 | 4 | 0 | 3 |
| RPL6 | TYSND1 | 0.669294 | 3 | 0 | 3 |
| RPL6 | SENP8 | 0.666499 | 3 | 0 | 3 |
| RPL6 | RPL3 | 0.665313 | 11 | 0 | 9 |
| RPL6 | RPL29 | 0.662267 | 11 | 0 | 9 |
| RPL6 | RPL11 | 0.640377 | 13 | 0 | 9 |
| RPL6 | USP54 | 0.64025 | 3 | 0 | 3 |
| RPL6 | RPS19 | 0.638414 | 6 | 0 | 6 |
| RPL6 | METAP1 | 0.637787 | 6 | 0 | 5 |
| RPL6 | RPS24 | 0.631514 | 11 | 0 | 9 |
| RPL6 | ARPC3 | 0.630996 | 8 | 0 | 7 |
| RPL6 | CNOT1 | 0.629967 | 6 | 0 | 4 |
| RPL6 | SPATA6 | 0.628622 | 3 | 0 | 3 |
| RPL6 | RPL5 | 0.627738 | 3 | 0 | 3 |
| RPL6 | RPS18 | 0.626521 | 13 | 0 | 10 |
| RPL6 | NDUFA12 | 0.623627 | 4 | 0 | 3 |
| RPL6 | MBP | 0.622181 | 3 | 0 | 3 |
For details and further investigation, click here
