| Full name: ribosomal protein S3 | Alias Symbol: FLJ26283|FLJ27450|MGC87870|S3 | ||
| Type: protein-coding gene | Cytoband: 11q13.4 | ||
| Entrez ID: 6188 | HGNC ID: HGNC:10420 | Ensembl Gene: ENSG00000149273 | OMIM ID: 600454 |
| Drug and gene relationship at DGIdb | |||
Expression of RPS3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RPS3 | 6188 | 208692_at | 0.0885 | 0.8082 | |
| GSE20347 | RPS3 | 6188 | 208692_at | -0.0566 | 0.7018 | |
| GSE23400 | RPS3 | 6188 | 208692_at | 0.2827 | 0.0001 | |
| GSE26886 | RPS3 | 6188 | 208692_at | -0.4691 | 0.0526 | |
| GSE29001 | RPS3 | 6188 | 208692_at | -0.2481 | 0.6354 | |
| GSE38129 | RPS3 | 6188 | 208692_at | 0.0319 | 0.8262 | |
| GSE45670 | RPS3 | 6188 | 208692_at | -0.2145 | 0.1260 | |
| GSE53622 | RPS3 | 6188 | 66360 | 0.4793 | 0.0000 | |
| GSE53624 | RPS3 | 6188 | 66360 | 0.4083 | 0.0000 | |
| GSE63941 | RPS3 | 6188 | 208692_at | 0.9697 | 0.0009 | |
| GSE77861 | RPS3 | 6188 | 208692_at | -0.2059 | 0.3710 | |
| GSE97050 | RPS3 | 6188 | A_32_P182941 | 0.1188 | 0.8135 | |
| SRP007169 | RPS3 | 6188 | RNAseq | -1.0472 | 0.0157 | |
| SRP008496 | RPS3 | 6188 | RNAseq | -0.6077 | 0.0969 | |
| SRP064894 | RPS3 | 6188 | RNAseq | -0.0951 | 0.7927 | |
| SRP133303 | RPS3 | 6188 | RNAseq | -0.9657 | 0.0000 | |
| SRP159526 | RPS3 | 6188 | RNAseq | -0.8889 | 0.0012 | |
| SRP193095 | RPS3 | 6188 | RNAseq | -0.9952 | 0.0000 | |
| SRP219564 | RPS3 | 6188 | RNAseq | -0.1778 | 0.5452 | |
| TCGA | RPS3 | 6188 | RNAseq | 0.0489 | 0.3788 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by RPS3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RPS3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RPS3 | 6188 | 6 | 8 | 16 | |
| GSE20123 | RPS3 | 6188 | 6 | 7 | 17 | |
| GSE43470 | RPS3 | 6188 | 5 | 4 | 34 | |
| GSE46452 | RPS3 | 6188 | 7 | 22 | 30 | |
| GSE47630 | RPS3 | 6188 | 6 | 14 | 20 | |
| GSE54993 | RPS3 | 6188 | 8 | 2 | 60 | |
| GSE54994 | RPS3 | 6188 | 7 | 16 | 30 | |
| GSE60625 | RPS3 | 6188 | 4 | 3 | 4 | |
| GSE74703 | RPS3 | 6188 | 4 | 3 | 29 | |
| GSE74704 | RPS3 | 6188 | 4 | 3 | 13 | |
| TCGA | RPS3 | 6188 | 21 | 32 | 43 |
Total number of gains: 78; Total number of losses: 114; Total Number of normals: 296.
Somatic mutations of RPS3:
Generating mutation plots.
Highly correlated genes for RPS3:
Showing top 20/294 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RPS3 | BORA | 0.752533 | 3 | 0 | 3 |
| RPS3 | TADA1 | 0.734338 | 3 | 0 | 3 |
| RPS3 | PPP4C | 0.73257 | 3 | 0 | 3 |
| RPS3 | IMP3 | 0.711626 | 3 | 0 | 3 |
| RPS3 | PEX11B | 0.707434 | 3 | 0 | 3 |
| RPS3 | MIA3 | 0.706343 | 3 | 0 | 3 |
| RPS3 | SYPL1 | 0.698714 | 3 | 0 | 3 |
| RPS3 | FH | 0.694476 | 3 | 0 | 3 |
| RPS3 | ZNF740 | 0.6933 | 3 | 0 | 3 |
| RPS3 | PRMT6 | 0.688699 | 3 | 0 | 3 |
| RPS3 | ZNF600 | 0.686163 | 3 | 0 | 3 |
| RPS3 | LYSMD1 | 0.683089 | 3 | 0 | 3 |
| RPS3 | EIF4H | 0.682782 | 3 | 0 | 3 |
| RPS3 | EEF2 | 0.68144 | 3 | 0 | 3 |
| RPS3 | STRBP | 0.679856 | 3 | 0 | 3 |
| RPS3 | TMBIM6 | 0.678473 | 3 | 0 | 3 |
| RPS3 | KHNYN | 0.67805 | 4 | 0 | 4 |
| RPS3 | CHCHD4 | 0.674389 | 4 | 0 | 4 |
| RPS3 | TYSND1 | 0.673255 | 3 | 0 | 3 |
| RPS3 | PAN2 | 0.6731 | 3 | 0 | 3 |
For details and further investigation, click here
