| Full name: neogenin 1 | Alias Symbol: NGN|HsT17534|IGDCC2|NTN1R2 | ||
| Type: protein-coding gene | Cytoband: 15q24.1 | ||
| Entrez ID: 4756 | HGNC ID: HGNC:7754 | Ensembl Gene: ENSG00000067141 | OMIM ID: 601907 |
| Drug and gene relationship at DGIdb | |||
Expression of NEO1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NEO1 | 4756 | 204321_at | 0.7821 | 0.0871 | |
| GSE20347 | NEO1 | 4756 | 204321_at | 0.9069 | 0.0001 | |
| GSE23400 | NEO1 | 4756 | 204321_at | 0.2429 | 0.0004 | |
| GSE26886 | NEO1 | 4756 | 225270_at | 1.3087 | 0.0000 | |
| GSE29001 | NEO1 | 4756 | 204321_at | 0.3963 | 0.2520 | |
| GSE38129 | NEO1 | 4756 | 204321_at | 0.7742 | 0.0000 | |
| GSE45670 | NEO1 | 4756 | 204321_at | 0.2979 | 0.2553 | |
| GSE53622 | NEO1 | 4756 | 23006 | 0.1376 | 0.3234 | |
| GSE53624 | NEO1 | 4756 | 23006 | 0.0983 | 0.4396 | |
| GSE63941 | NEO1 | 4756 | 204321_at | -2.0348 | 0.0308 | |
| GSE77861 | NEO1 | 4756 | 204321_at | 0.4671 | 0.0779 | |
| GSE97050 | NEO1 | 4756 | A_33_P3651948 | -0.5414 | 0.2423 | |
| SRP007169 | NEO1 | 4756 | RNAseq | 1.4039 | 0.0002 | |
| SRP008496 | NEO1 | 4756 | RNAseq | 1.8301 | 0.0000 | |
| SRP064894 | NEO1 | 4756 | RNAseq | 0.1804 | 0.3417 | |
| SRP133303 | NEO1 | 4756 | RNAseq | 0.5437 | 0.0022 | |
| SRP159526 | NEO1 | 4756 | RNAseq | 0.7678 | 0.0000 | |
| SRP193095 | NEO1 | 4756 | RNAseq | 0.4658 | 0.0007 | |
| SRP219564 | NEO1 | 4756 | RNAseq | -0.3965 | 0.4563 | |
| TCGA | NEO1 | 4756 | RNAseq | -0.1296 | 0.0883 |
Upregulated datasets: 3; Downregulated datasets: 1.
Survival by NEO1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NEO1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NEO1 | 4756 | 8 | 0 | 22 | |
| GSE20123 | NEO1 | 4756 | 8 | 0 | 22 | |
| GSE43470 | NEO1 | 4756 | 4 | 6 | 33 | |
| GSE46452 | NEO1 | 4756 | 3 | 7 | 49 | |
| GSE47630 | NEO1 | 4756 | 8 | 10 | 22 | |
| GSE54993 | NEO1 | 4756 | 5 | 6 | 59 | |
| GSE54994 | NEO1 | 4756 | 5 | 9 | 39 | |
| GSE60625 | NEO1 | 4756 | 4 | 4 | 3 | |
| GSE74703 | NEO1 | 4756 | 4 | 3 | 29 | |
| GSE74704 | NEO1 | 4756 | 4 | 0 | 16 | |
| TCGA | NEO1 | 4756 | 12 | 15 | 69 |
Total number of gains: 65; Total number of losses: 60; Total Number of normals: 363.
Somatic mutations of NEO1:
Generating mutation plots.
Highly correlated genes for NEO1:
Showing top 20/1004 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NEO1 | SIX4 | 0.8066 | 3 | 0 | 3 |
| NEO1 | TSC22D1 | 0.790037 | 3 | 0 | 3 |
| NEO1 | ZNF251 | 0.735403 | 3 | 0 | 3 |
| NEO1 | HNRNPA1 | 0.710271 | 4 | 0 | 4 |
| NEO1 | SIMC1 | 0.709421 | 3 | 0 | 3 |
| NEO1 | WDR81 | 0.705134 | 4 | 0 | 4 |
| NEO1 | TSNARE1 | 0.704314 | 3 | 0 | 3 |
| NEO1 | ZFP1 | 0.696224 | 3 | 0 | 3 |
| NEO1 | TMEM216 | 0.695872 | 4 | 0 | 4 |
| NEO1 | ARID2 | 0.694926 | 3 | 0 | 3 |
| NEO1 | PLEKHA3 | 0.693572 | 5 | 0 | 5 |
| NEO1 | LNP1 | 0.692511 | 3 | 0 | 3 |
| NEO1 | NPHP3 | 0.686993 | 3 | 0 | 3 |
| NEO1 | GHDC | 0.681302 | 3 | 0 | 3 |
| NEO1 | BOD1 | 0.678469 | 4 | 0 | 3 |
| NEO1 | PCGF6 | 0.677839 | 3 | 0 | 3 |
| NEO1 | C20orf194 | 0.676403 | 4 | 0 | 4 |
| NEO1 | STAT5B | 0.67348 | 3 | 0 | 3 |
| NEO1 | SFT2D3 | 0.672213 | 4 | 0 | 4 |
| NEO1 | PIGH | 0.671701 | 3 | 0 | 3 |
For details and further investigation, click here
