| Full name: ribonuclease P RNA component H1 | Alias Symbol: H1RNA|RPPH1-1 | ||
| Type: non-coding RNA | Cytoband: 14q11.2 | ||
| Entrez ID: 85495 | HGNC ID: HGNC:19273 | Ensembl Gene: ENSG00000277209 | OMIM ID: 608513 |
| Drug and gene relationship at DGIdb | |||
Expression of RPPH1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RPPH1 | 85495 | 1556684_at | -0.1405 | 0.5956 | |
| GSE26886 | RPPH1 | 85495 | 1556684_at | 0.0750 | 0.4993 | |
| GSE45670 | RPPH1 | 85495 | 1556684_at | 0.0716 | 0.4494 | |
| GSE63941 | RPPH1 | 85495 | 1556684_at | -0.0457 | 0.8426 | |
| GSE77861 | RPPH1 | 85495 | 1556684_at | -0.0643 | 0.5565 | |
| SRP007169 | RPPH1 | 85495 | RNAseq | -1.7873 | 0.0003 | |
| SRP008496 | RPPH1 | 85495 | RNAseq | -1.0231 | 0.0225 | |
| SRP133303 | RPPH1 | 85495 | RNAseq | -0.4598 | 0.0197 | |
| SRP193095 | RPPH1 | 85495 | RNAseq | -1.0024 | 0.0001 | |
| TCGA | RPPH1 | 85495 | RNAseq | -0.0953 | 0.4028 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by RPPH1 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of RPPH1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RPPH1 | 85495 | 11 | 3 | 16 | |
| GSE20123 | RPPH1 | 85495 | 9 | 3 | 18 | |
| GSE43470 | RPPH1 | 85495 | 7 | 1 | 35 | |
| GSE46452 | RPPH1 | 85495 | 19 | 2 | 38 | |
| GSE47630 | RPPH1 | 85495 | 10 | 10 | 20 | |
| GSE54993 | RPPH1 | 85495 | 3 | 11 | 56 | |
| GSE54994 | RPPH1 | 85495 | 18 | 5 | 30 | |
| GSE60625 | RPPH1 | 85495 | 0 | 2 | 9 | |
| GSE74703 | RPPH1 | 85495 | 6 | 1 | 29 | |
| GSE74704 | RPPH1 | 85495 | 4 | 2 | 14 | |
| TCGA | RPPH1 | 85495 | 28 | 16 | 52 |
Total number of gains: 115; Total number of losses: 56; Total Number of normals: 317.
Somatic mutations of RPPH1:
Generating mutation plots.
Highly correlated genes for RPPH1:
Showing top 20/21 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RPPH1 | HTR4 | 0.663002 | 3 | 0 | 3 |
| RPPH1 | GSC | 0.656872 | 3 | 0 | 3 |
| RPPH1 | SPINT3 | 0.630115 | 3 | 0 | 3 |
| RPPH1 | CECR7 | 0.608889 | 3 | 0 | 3 |
| RPPH1 | TXNDC2 | 0.605921 | 3 | 0 | 3 |
| RPPH1 | TMEM106A | 0.603474 | 4 | 0 | 3 |
| RPPH1 | LINC01310 | 0.59954 | 3 | 0 | 3 |
| RPPH1 | KIAA0408 | 0.598265 | 3 | 0 | 3 |
| RPPH1 | PKD2L1 | 0.596886 | 4 | 0 | 4 |
| RPPH1 | ASB11 | 0.578879 | 3 | 0 | 3 |
| RPPH1 | CEACAM21 | 0.567802 | 3 | 0 | 3 |
| RPPH1 | TAC3 | 0.567645 | 4 | 0 | 3 |
| RPPH1 | SCTR | 0.556552 | 3 | 0 | 3 |
| RPPH1 | GP9 | 0.555256 | 4 | 0 | 3 |
| RPPH1 | SSTR2 | 0.554601 | 3 | 0 | 3 |
| RPPH1 | TM4SF5 | 0.544539 | 3 | 0 | 3 |
| RPPH1 | SLC5A2 | 0.538798 | 3 | 0 | 3 |
| RPPH1 | SUN5 | 0.533508 | 4 | 0 | 3 |
| RPPH1 | KCNQ1DN | 0.531172 | 4 | 0 | 3 |
| RPPH1 | GABRG1 | 0.529814 | 3 | 0 | 3 |
For details and further investigation, click here
