| Full name: transmembrane 4 L six family member 5 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 17p13.2 | ||
| Entrez ID: 9032 | HGNC ID: HGNC:11857 | Ensembl Gene: ENSG00000142484 | OMIM ID: 604657 |
| Drug and gene relationship at DGIdb | |||
Expression of TM4SF5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TM4SF5 | 9032 | 206242_at | 0.0648 | 0.8253 | |
| GSE20347 | TM4SF5 | 9032 | 206242_at | -0.0658 | 0.2994 | |
| GSE23400 | TM4SF5 | 9032 | 206242_at | -0.0565 | 0.0570 | |
| GSE26886 | TM4SF5 | 9032 | 206242_at | 0.0524 | 0.6630 | |
| GSE29001 | TM4SF5 | 9032 | 206242_at | -0.1061 | 0.4912 | |
| GSE38129 | TM4SF5 | 9032 | 206242_at | -0.1697 | 0.0070 | |
| GSE45670 | TM4SF5 | 9032 | 206242_at | 0.0167 | 0.8968 | |
| GSE53622 | TM4SF5 | 9032 | 35254 | -0.0033 | 0.9829 | |
| GSE53624 | TM4SF5 | 9032 | 35254 | -0.6255 | 0.0000 | |
| GSE63941 | TM4SF5 | 9032 | 206242_at | 0.2678 | 0.0123 | |
| GSE77861 | TM4SF5 | 9032 | 206242_at | -0.0708 | 0.5872 | |
| TCGA | TM4SF5 | 9032 | RNAseq | -6.1315 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by TM4SF5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TM4SF5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TM4SF5 | 9032 | 5 | 2 | 23 | |
| GSE20123 | TM4SF5 | 9032 | 5 | 3 | 22 | |
| GSE43470 | TM4SF5 | 9032 | 1 | 6 | 36 | |
| GSE46452 | TM4SF5 | 9032 | 34 | 1 | 24 | |
| GSE47630 | TM4SF5 | 9032 | 7 | 1 | 32 | |
| GSE54993 | TM4SF5 | 9032 | 4 | 3 | 63 | |
| GSE54994 | TM4SF5 | 9032 | 5 | 9 | 39 | |
| GSE60625 | TM4SF5 | 9032 | 4 | 0 | 7 | |
| GSE74703 | TM4SF5 | 9032 | 1 | 3 | 32 | |
| GSE74704 | TM4SF5 | 9032 | 3 | 1 | 16 | |
| TCGA | TM4SF5 | 9032 | 19 | 21 | 56 |
Total number of gains: 88; Total number of losses: 50; Total Number of normals: 350.
Somatic mutations of TM4SF5:
Generating mutation plots.
Highly correlated genes for TM4SF5:
Showing top 20/966 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TM4SF5 | KLK14 | 0.760757 | 3 | 0 | 3 |
| TM4SF5 | MEIS3 | 0.755698 | 3 | 0 | 3 |
| TM4SF5 | LRRC46 | 0.727484 | 3 | 0 | 3 |
| TM4SF5 | TPBGL | 0.704948 | 3 | 0 | 3 |
| TM4SF5 | PGC | 0.704571 | 6 | 0 | 5 |
| TM4SF5 | NEUROD4 | 0.687771 | 7 | 0 | 7 |
| TM4SF5 | MAPT-AS1 | 0.685773 | 3 | 0 | 3 |
| TM4SF5 | C20orf203 | 0.681572 | 3 | 0 | 3 |
| TM4SF5 | IL34 | 0.678719 | 3 | 0 | 3 |
| TM4SF5 | DNAH11 | 0.671948 | 3 | 0 | 3 |
| TM4SF5 | SP7 | 0.6712 | 3 | 0 | 3 |
| TM4SF5 | PSD | 0.667126 | 4 | 0 | 4 |
| TM4SF5 | HTR1D | 0.663903 | 4 | 0 | 4 |
| TM4SF5 | ADM2 | 0.663611 | 7 | 0 | 7 |
| TM4SF5 | LIPF | 0.663481 | 5 | 0 | 5 |
| TM4SF5 | SAMD10 | 0.663433 | 3 | 0 | 3 |
| TM4SF5 | EGR4 | 0.661985 | 7 | 0 | 7 |
| TM4SF5 | RHAG | 0.661826 | 6 | 0 | 4 |
| TM4SF5 | TPSG1 | 0.66119 | 7 | 0 | 6 |
| TM4SF5 | PHGR1 | 0.659557 | 5 | 0 | 3 |
For details and further investigation, click here
