| Full name: ribosomal RNA processing 15 homolog | Alias Symbol: CGI-115 | ||
| Type: protein-coding gene | Cytoband: 1q41 | ||
| Entrez ID: 51018 | HGNC ID: HGNC:24255 | Ensembl Gene: ENSG00000067533 | OMIM ID: 611193 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of RRP15:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RRP15 | 51018 | 219037_at | 0.8571 | 0.1223 | |
| GSE20347 | RRP15 | 51018 | 219037_at | 0.8404 | 0.0011 | |
| GSE23400 | RRP15 | 51018 | 219037_at | 0.8347 | 0.0000 | |
| GSE26886 | RRP15 | 51018 | 219037_at | 0.9236 | 0.0000 | |
| GSE29001 | RRP15 | 51018 | 219037_at | 1.0512 | 0.0196 | |
| GSE38129 | RRP15 | 51018 | 219037_at | 0.9830 | 0.0000 | |
| GSE45670 | RRP15 | 51018 | 219037_at | 0.6974 | 0.0006 | |
| GSE53622 | RRP15 | 51018 | 29174 | 0.4557 | 0.0000 | |
| GSE53624 | RRP15 | 51018 | 29174 | 0.9267 | 0.0000 | |
| GSE63941 | RRP15 | 51018 | 219037_at | 0.5051 | 0.3672 | |
| GSE77861 | RRP15 | 51018 | 219037_at | 0.8724 | 0.0072 | |
| GSE97050 | RRP15 | 51018 | A_23_P23356 | 0.3025 | 0.3879 | |
| SRP007169 | RRP15 | 51018 | RNAseq | 0.7064 | 0.1139 | |
| SRP008496 | RRP15 | 51018 | RNAseq | 1.5268 | 0.0009 | |
| SRP064894 | RRP15 | 51018 | RNAseq | 0.2189 | 0.1023 | |
| SRP133303 | RRP15 | 51018 | RNAseq | 0.6025 | 0.0027 | |
| SRP159526 | RRP15 | 51018 | RNAseq | 0.3069 | 0.3287 | |
| SRP193095 | RRP15 | 51018 | RNAseq | 0.3341 | 0.0002 | |
| SRP219564 | RRP15 | 51018 | RNAseq | 0.4180 | 0.1503 | |
| TCGA | RRP15 | 51018 | RNAseq | 0.0302 | 0.5725 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by RRP15 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RRP15:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RRP15 | 51018 | 9 | 0 | 21 | |
| GSE20123 | RRP15 | 51018 | 9 | 0 | 21 | |
| GSE43470 | RRP15 | 51018 | 8 | 1 | 34 | |
| GSE46452 | RRP15 | 51018 | 3 | 1 | 55 | |
| GSE47630 | RRP15 | 51018 | 15 | 0 | 25 | |
| GSE54993 | RRP15 | 51018 | 0 | 6 | 64 | |
| GSE54994 | RRP15 | 51018 | 15 | 0 | 38 | |
| GSE60625 | RRP15 | 51018 | 0 | 0 | 11 | |
| GSE74703 | RRP15 | 51018 | 8 | 1 | 27 | |
| GSE74704 | RRP15 | 51018 | 3 | 0 | 17 | |
| TCGA | RRP15 | 51018 | 45 | 3 | 48 |
Total number of gains: 115; Total number of losses: 12; Total Number of normals: 361.
Somatic mutations of RRP15:
Generating mutation plots.
Highly correlated genes for RRP15:
Showing top 20/2024 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RRP15 | TYW5 | 0.806466 | 3 | 0 | 3 |
| RRP15 | C1orf131 | 0.786002 | 8 | 0 | 8 |
| RRP15 | CPSF6 | 0.779732 | 11 | 0 | 11 |
| RRP15 | HEATR1 | 0.76926 | 13 | 0 | 12 |
| RRP15 | PFDN2 | 0.761846 | 11 | 0 | 11 |
| RRP15 | CEP95 | 0.761251 | 3 | 0 | 3 |
| RRP15 | DNAJC2 | 0.760406 | 11 | 0 | 11 |
| RRP15 | ZFHX3 | 0.756826 | 3 | 0 | 3 |
| RRP15 | MRPS17 | 0.756413 | 8 | 0 | 8 |
| RRP15 | RGS1 | 0.755036 | 3 | 0 | 3 |
| RRP15 | GNAI1 | 0.754548 | 3 | 0 | 3 |
| RRP15 | TIMM17A | 0.750781 | 11 | 0 | 11 |
| RRP15 | SLC25A29 | 0.747532 | 3 | 0 | 3 |
| RRP15 | TMEM181 | 0.740906 | 3 | 0 | 3 |
| RRP15 | MRPL9 | 0.74059 | 9 | 0 | 9 |
| RRP15 | SNRPE | 0.739735 | 13 | 0 | 12 |
| RRP15 | DDX55 | 0.739133 | 7 | 0 | 7 |
| RRP15 | ISG20L2 | 0.73885 | 10 | 0 | 10 |
| RRP15 | CBFA2T2 | 0.737359 | 3 | 0 | 3 |
| RRP15 | CCT6A | 0.736702 | 8 | 0 | 8 |
For details and further investigation, click here
