SNRPE

 

Full name: small nuclear ribonucleoprotein polypeptide E Alias Symbol: Sm-E
Type: protein-coding gene Cytoband: 1q32.1
Entrez ID: 6635 HGNC ID: HGNC:11161 Ensembl Gene: ENSG00000182004 OMIM ID: 128260
Drug and gene relationship at DGIdb

 

Expression of SNRPE:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 SNRPE 6635 203316_s_at 0.6749 0.0545
GSE20347 SNRPE 6635 203316_s_at 0.8977 0.0000
GSE23400 SNRPE 6635 203316_s_at 0.9998 0.0000
GSE26886 SNRPE 6635 203316_s_at 0.7435 0.0003
GSE29001 SNRPE 6635 203316_s_at 0.8070 0.0446
GSE38129 SNRPE 6635 203316_s_at 1.0220 0.0000
GSE45670 SNRPE 6635 203316_s_at 0.5024 0.0009
GSE53622 SNRPE 6635 74088 0.8213 0.0000
GSE53624 SNRPE 6635 74088 1.1074 0.0000
GSE63941 SNRPE 6635 203316_s_at 0.9952 0.0001
GSE77861 SNRPE 6635 203316_s_at 0.7319 0.0013
GSE97050 SNRPE 6635 A_23_P126291 0.4851 0.1895
SRP007169 SNRPE 6635 RNAseq 0.7096 0.0586
SRP008496 SNRPE 6635 RNAseq 0.8085 0.0185
SRP064894 SNRPE 6635 RNAseq 0.6881 0.0073
SRP133303 SNRPE 6635 RNAseq 0.8911 0.0000
SRP159526 SNRPE 6635 RNAseq 0.9808 0.0000
SRP193095 SNRPE 6635 RNAseq 0.1789 0.2685
SRP219564 SNRPE 6635 RNAseq 0.6794 0.0486
TCGA SNRPE 6635 RNAseq 0.3728 0.0000

Upregulated datasets: 2; Downregulated datasets: 0.  

 

Survival by SNRPE expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of SNRPE:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 SNRPE 6635 11 0 19
GSE20123 SNRPE 6635 11 0 19
GSE43470 SNRPE 6635 6 0 37
GSE46452 SNRPE 6635 3 1 55
GSE47630 SNRPE 6635 14 0 26
GSE54993 SNRPE 6635 0 6 64
GSE54994 SNRPE 6635 15 0 38
GSE60625 SNRPE 6635 0 0 11
GSE74703 SNRPE 6635 6 0 30
GSE74704 SNRPE 6635 5 0 15
TCGA SNRPE 6635 43 4 49

Total number of gains: 114; Total number of losses: 11; Total Number of normals: 363.  

 

Somatic mutations of SNRPE:

 

Generating mutation plots.

 

Highly correlated genes for SNRPE:

 

Showing top 20/2153 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
SNRPECPT1A0.840975303
SNRPECDCA70.801677606
SNRPEEIF3C0.799583303
SNRPEPARP10.78850512012
SNRPECBX30.78743510010
SNRPEPSMB40.78596811011
SNRPEPTDSS10.78464911010
SNRPECENPF0.78425212012
SNRPESIX40.77269707
SNRPERFC40.77244112012
SNRPECKS1B0.77203813012
SNRPEMCM30.77183911011
SNRPEMSTO10.77152606
SNRPEGMNN0.77130213012
SNRPENUF20.771032807
SNRPECPSF60.76949912012
SNRPEDNMT10.76854112012
SNRPECACYBP0.76682412011
SNRPEKIF140.76614612012
SNRPEECT20.76404711011

For details and further investigation, click here