TIMM17A

 

Full name: translocase of inner mitochondrial membrane 17A Alias Symbol: TIM17|TIM17A
Type: protein-coding gene Cytoband: 1q32.1
Entrez ID: 10440 HGNC ID: HGNC:17315 Ensembl Gene: ENSG00000134375 OMIM ID: 605057
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of TIMM17A:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 TIMM17A 10440 215171_s_at 0.5307 0.0782
GSE20347 TIMM17A 10440 215171_s_at 0.5687 0.0001
GSE23400 TIMM17A 10440 215171_s_at 0.4623 0.0000
GSE26886 TIMM17A 10440 215171_s_at 0.2147 0.3145
GSE29001 TIMM17A 10440 215171_s_at 0.6156 0.0718
GSE38129 TIMM17A 10440 215171_s_at 0.6056 0.0000
GSE45670 TIMM17A 10440 215171_s_at 0.4303 0.0008
GSE53622 TIMM17A 10440 25641 0.3929 0.0000
GSE53624 TIMM17A 10440 25641 0.5952 0.0000
GSE63941 TIMM17A 10440 215171_s_at -0.5485 0.1126
GSE77861 TIMM17A 10440 215171_s_at 0.5445 0.0210
GSE97050 TIMM17A 10440 A_23_P126970 0.3478 0.3339
SRP007169 TIMM17A 10440 RNAseq 0.0794 0.8262
SRP008496 TIMM17A 10440 RNAseq 0.1908 0.4172
SRP064894 TIMM17A 10440 RNAseq 0.3387 0.0189
SRP133303 TIMM17A 10440 RNAseq 0.7557 0.0000
SRP159526 TIMM17A 10440 RNAseq 0.6552 0.0486
SRP193095 TIMM17A 10440 RNAseq 0.0480 0.7057
SRP219564 TIMM17A 10440 RNAseq 0.4661 0.1812
TCGA TIMM17A 10440 RNAseq 0.0481 0.3185

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by TIMM17A expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of TIMM17A:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 TIMM17A 10440 11 0 19
GSE20123 TIMM17A 10440 11 0 19
GSE43470 TIMM17A 10440 6 0 37
GSE46452 TIMM17A 10440 3 1 55
GSE47630 TIMM17A 10440 14 0 26
GSE54993 TIMM17A 10440 0 6 64
GSE54994 TIMM17A 10440 15 0 38
GSE60625 TIMM17A 10440 0 0 11
GSE74703 TIMM17A 10440 6 0 30
GSE74704 TIMM17A 10440 5 0 15
TCGA TIMM17A 10440 43 4 49

Total number of gains: 114; Total number of losses: 11; Total Number of normals: 363.  

 

Somatic mutations of TIMM17A:

 

Generating mutation plots.

 

Highly correlated genes for TIMM17A:

 

Showing top 20/1172 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
TIMM17ARRP150.75078111011
TIMM17ADESI20.72590110010
TIMM17APNPT10.717632606
TIMM17AHAT10.70575911011
TIMM17ACDCA20.699951404
TIMM17AMTERF30.698537808
TIMM17AMTBP0.698224505
TIMM17ADUSP120.69411611010
TIMM17APPP3R10.69245303
TIMM17ATAF1A0.69171411010
TIMM17ACBX30.69155210010
TIMM17ATFB2M0.68830511010
TIMM17ANDUFB90.688202505
TIMM17ACCT30.6846311009
TIMM17AMDM40.680565303
TIMM17ASPAG50.67951908
TIMM17ANUF20.678663606
TIMM17APFDN20.6770981009
TIMM17AHSPE10.67700511011
TIMM17AEBNA1BP20.674811303

For details and further investigation, click here