| Full name: reticulon 2 | Alias Symbol: NSP2|NSPL1 | ||
| Type: protein-coding gene | Cytoband: 19q13.32 | ||
| Entrez ID: 6253 | HGNC ID: HGNC:10468 | Ensembl Gene: ENSG00000125744 | OMIM ID: 603183 |
| Drug and gene relationship at DGIdb | |||
Expression of RTN2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RTN2 | 6253 | 34408_at | -0.0577 | 0.8915 | |
| GSE20347 | RTN2 | 6253 | 34408_at | 0.3331 | 0.0098 | |
| GSE23400 | RTN2 | 6253 | 34408_at | 0.1058 | 0.0039 | |
| GSE26886 | RTN2 | 6253 | 204217_s_at | 0.1080 | 0.4485 | |
| GSE29001 | RTN2 | 6253 | 34408_at | 0.2009 | 0.2210 | |
| GSE38129 | RTN2 | 6253 | 34408_at | 0.0846 | 0.6698 | |
| GSE45670 | RTN2 | 6253 | 34408_at | 0.0791 | 0.6510 | |
| GSE53622 | RTN2 | 6253 | 38892 | 0.0891 | 0.5292 | |
| GSE53624 | RTN2 | 6253 | 38892 | 0.3139 | 0.0005 | |
| GSE63941 | RTN2 | 6253 | 34408_at | -1.5655 | 0.0223 | |
| GSE77861 | RTN2 | 6253 | 204217_s_at | -0.0214 | 0.9018 | |
| GSE97050 | RTN2 | 6253 | A_23_P89902 | 0.0382 | 0.8995 | |
| SRP064894 | RTN2 | 6253 | RNAseq | 1.0269 | 0.0100 | |
| SRP133303 | RTN2 | 6253 | RNAseq | 0.0293 | 0.9298 | |
| SRP159526 | RTN2 | 6253 | RNAseq | 0.2882 | 0.4135 | |
| SRP219564 | RTN2 | 6253 | RNAseq | -0.3135 | 0.6385 | |
| TCGA | RTN2 | 6253 | RNAseq | 0.1151 | 0.3758 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by RTN2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RTN2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RTN2 | 6253 | 4 | 5 | 21 | |
| GSE20123 | RTN2 | 6253 | 4 | 4 | 22 | |
| GSE43470 | RTN2 | 6253 | 3 | 11 | 29 | |
| GSE46452 | RTN2 | 6253 | 45 | 1 | 13 | |
| GSE47630 | RTN2 | 6253 | 8 | 6 | 26 | |
| GSE54993 | RTN2 | 6253 | 17 | 4 | 49 | |
| GSE54994 | RTN2 | 6253 | 6 | 12 | 35 | |
| GSE60625 | RTN2 | 6253 | 9 | 0 | 2 | |
| GSE74703 | RTN2 | 6253 | 3 | 7 | 26 | |
| GSE74704 | RTN2 | 6253 | 4 | 2 | 14 | |
| TCGA | RTN2 | 6253 | 15 | 16 | 65 |
Total number of gains: 118; Total number of losses: 68; Total Number of normals: 302.
Somatic mutations of RTN2:
Generating mutation plots.
Highly correlated genes for RTN2:
Showing top 20/657 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RTN2 | ZNF540 | 0.782055 | 3 | 0 | 3 |
| RTN2 | EID3 | 0.772968 | 3 | 0 | 3 |
| RTN2 | STAT5B | 0.767922 | 3 | 0 | 3 |
| RTN2 | C20orf194 | 0.764152 | 3 | 0 | 3 |
| RTN2 | PLEKHB1 | 0.738185 | 3 | 0 | 3 |
| RTN2 | OAZ2 | 0.73233 | 3 | 0 | 3 |
| RTN2 | GRIN3A | 0.731133 | 3 | 0 | 3 |
| RTN2 | SH3GL2 | 0.715714 | 3 | 0 | 3 |
| RTN2 | CCDC102B | 0.709707 | 3 | 0 | 3 |
| RTN2 | RNF14 | 0.70899 | 3 | 0 | 3 |
| RTN2 | UBXN10 | 0.708037 | 3 | 0 | 3 |
| RTN2 | FGFR1 | 0.69904 | 3 | 0 | 3 |
| RTN2 | PODN | 0.694434 | 3 | 0 | 3 |
| RTN2 | LRRC14 | 0.691661 | 3 | 0 | 3 |
| RTN2 | FGF7 | 0.691122 | 4 | 0 | 4 |
| RTN2 | ITPR1 | 0.687196 | 5 | 0 | 4 |
| RTN2 | CSDE1 | 0.680409 | 3 | 0 | 3 |
| RTN2 | DOCK11 | 0.679935 | 4 | 0 | 3 |
| RTN2 | ASB5 | 0.672341 | 3 | 0 | 3 |
| RTN2 | FIBIN | 0.67017 | 3 | 0 | 3 |
For details and further investigation, click here
