| Full name: zinc finger protein 540 | Alias Symbol: DKFZp547B0714 | ||
| Type: protein-coding gene | Cytoband: 19q13.13 | ||
| Entrez ID: 163255 | HGNC ID: HGNC:25331 | Ensembl Gene: ENSG00000171817 | OMIM ID: 613903 |
| Drug and gene relationship at DGIdb | |||
Expression of ZNF540:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF540 | 163255 | 242697_at | -0.3612 | 0.2760 | |
| GSE26886 | ZNF540 | 163255 | 242697_at | -0.0271 | 0.8465 | |
| GSE45670 | ZNF540 | 163255 | 242697_at | -0.1000 | 0.3793 | |
| GSE63941 | ZNF540 | 163255 | 242697_at | -0.1696 | 0.3173 | |
| GSE77861 | ZNF540 | 163255 | 242697_at | -0.0533 | 0.6404 | |
| GSE97050 | ZNF540 | 163255 | A_23_P90542 | -0.2703 | 0.2269 | |
| SRP064894 | ZNF540 | 163255 | RNAseq | -0.7989 | 0.0094 | |
| SRP133303 | ZNF540 | 163255 | RNAseq | -1.3348 | 0.0001 | |
| SRP159526 | ZNF540 | 163255 | RNAseq | -1.4111 | 0.0004 | |
| SRP193095 | ZNF540 | 163255 | RNAseq | -1.3857 | 0.0000 | |
| SRP219564 | ZNF540 | 163255 | RNAseq | -0.7646 | 0.1780 | |
| TCGA | ZNF540 | 163255 | RNAseq | -1.3589 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by ZNF540 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of ZNF540:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF540 | 163255 | 7 | 4 | 19 | |
| GSE20123 | ZNF540 | 163255 | 7 | 3 | 20 | |
| GSE43470 | ZNF540 | 163255 | 4 | 10 | 29 | |
| GSE46452 | ZNF540 | 163255 | 47 | 2 | 10 | |
| GSE47630 | ZNF540 | 163255 | 9 | 5 | 26 | |
| GSE54993 | ZNF540 | 163255 | 17 | 3 | 50 | |
| GSE54994 | ZNF540 | 163255 | 6 | 9 | 38 | |
| GSE60625 | ZNF540 | 163255 | 9 | 0 | 2 | |
| GSE74703 | ZNF540 | 163255 | 4 | 6 | 26 | |
| GSE74704 | ZNF540 | 163255 | 7 | 1 | 12 | |
| TCGA | ZNF540 | 163255 | 19 | 15 | 62 |
Total number of gains: 136; Total number of losses: 58; Total Number of normals: 294.
Somatic mutations of ZNF540:
Generating mutation plots.
Highly correlated genes for ZNF540:
Showing top 20/101 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF540 | ITPR1 | 0.818218 | 3 | 0 | 3 |
| ZNF540 | FAM149B1 | 0.788042 | 3 | 0 | 3 |
| ZNF540 | RTN2 | 0.782055 | 3 | 0 | 3 |
| ZNF540 | CLIP3 | 0.775815 | 3 | 0 | 3 |
| ZNF540 | RRAS | 0.761944 | 3 | 0 | 3 |
| ZNF540 | ARHGEF15 | 0.75614 | 3 | 0 | 3 |
| ZNF540 | BTD | 0.751555 | 3 | 0 | 3 |
| ZNF540 | CSF1 | 0.741566 | 3 | 0 | 3 |
| ZNF540 | NPTX1 | 0.739181 | 3 | 0 | 3 |
| ZNF540 | UBXN10 | 0.738517 | 3 | 0 | 3 |
| ZNF540 | CKMT2 | 0.737875 | 3 | 0 | 3 |
| ZNF540 | SOX17 | 0.735114 | 3 | 0 | 3 |
| ZNF540 | BCL6 | 0.718661 | 3 | 0 | 3 |
| ZNF540 | CADM3 | 0.711758 | 3 | 0 | 3 |
| ZNF540 | NCAM1 | 0.710673 | 3 | 0 | 3 |
| ZNF540 | ITIH6 | 0.706193 | 3 | 0 | 3 |
| ZNF540 | SERPINA5 | 0.704121 | 3 | 0 | 3 |
| ZNF540 | ROR1 | 0.699168 | 3 | 0 | 3 |
| ZNF540 | TIRAP | 0.689421 | 3 | 0 | 3 |
| ZNF540 | ZBTB16 | 0.67736 | 4 | 0 | 3 |
For details and further investigation, click here
