| Full name: S100 calcium binding protein A3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1q21.3 | ||
| Entrez ID: 6274 | HGNC ID: HGNC:10493 | Ensembl Gene: ENSG00000188015 | OMIM ID: 176992 |
| Drug and gene relationship at DGIdb | |||
Expression of S100A3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | S100A3 | 6274 | 206027_at | 0.4573 | 0.6051 | |
| GSE20347 | S100A3 | 6274 | 206027_at | 0.0847 | 0.7386 | |
| GSE23400 | S100A3 | 6274 | 206027_at | 0.2098 | 0.0331 | |
| GSE26886 | S100A3 | 6274 | 206027_at | -0.3110 | 0.1365 | |
| GSE29001 | S100A3 | 6274 | 206027_at | -0.3270 | 0.3555 | |
| GSE38129 | S100A3 | 6274 | 206027_at | 0.3325 | 0.1071 | |
| GSE45670 | S100A3 | 6274 | 206027_at | 0.4848 | 0.0641 | |
| GSE53622 | S100A3 | 6274 | 93606 | 0.1532 | 0.4068 | |
| GSE53624 | S100A3 | 6274 | 93606 | 0.0823 | 0.5536 | |
| GSE63941 | S100A3 | 6274 | 206027_at | 0.1159 | 0.8221 | |
| GSE77861 | S100A3 | 6274 | 206027_at | 0.3053 | 0.4941 | |
| GSE97050 | S100A3 | 6274 | A_23_P104073 | 0.3014 | 0.3370 | |
| SRP064894 | S100A3 | 6274 | RNAseq | 1.1382 | 0.0079 | |
| SRP133303 | S100A3 | 6274 | RNAseq | 1.2788 | 0.0103 | |
| SRP159526 | S100A3 | 6274 | RNAseq | -0.8086 | 0.0999 | |
| SRP219564 | S100A3 | 6274 | RNAseq | -1.0072 | 0.1210 | |
| TCGA | S100A3 | 6274 | RNAseq | 1.6610 | 0.0000 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by S100A3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of S100A3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | S100A3 | 6274 | 14 | 0 | 16 | |
| GSE20123 | S100A3 | 6274 | 14 | 0 | 16 | |
| GSE43470 | S100A3 | 6274 | 6 | 2 | 35 | |
| GSE46452 | S100A3 | 6274 | 2 | 1 | 56 | |
| GSE47630 | S100A3 | 6274 | 15 | 0 | 25 | |
| GSE54993 | S100A3 | 6274 | 0 | 4 | 66 | |
| GSE54994 | S100A3 | 6274 | 16 | 0 | 37 | |
| GSE60625 | S100A3 | 6274 | 0 | 0 | 11 | |
| GSE74703 | S100A3 | 6274 | 6 | 1 | 29 | |
| GSE74704 | S100A3 | 6274 | 7 | 0 | 13 | |
| TCGA | S100A3 | 6274 | 39 | 1 | 56 |
Total number of gains: 119; Total number of losses: 9; Total Number of normals: 360.
Somatic mutations of S100A3:
Generating mutation plots.
Highly correlated genes for S100A3:
Showing top 20/177 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| S100A3 | FAM210A | 0.665105 | 3 | 0 | 3 |
| S100A3 | F2RL1 | 0.662278 | 4 | 0 | 4 |
| S100A3 | SMPD3 | 0.658148 | 3 | 0 | 3 |
| S100A3 | CEACAM19 | 0.645578 | 4 | 0 | 3 |
| S100A3 | GJB3 | 0.644653 | 10 | 0 | 8 |
| S100A3 | CYB5R2 | 0.641293 | 5 | 0 | 3 |
| S100A3 | ALOXE3 | 0.636987 | 4 | 0 | 3 |
| S100A3 | FERMT1 | 0.633086 | 6 | 0 | 4 |
| S100A3 | RGS20 | 0.632145 | 9 | 0 | 6 |
| S100A3 | SFN | 0.625637 | 10 | 0 | 9 |
| S100A3 | HOXD11 | 0.624263 | 3 | 0 | 3 |
| S100A3 | SUGCT | 0.618369 | 3 | 0 | 3 |
| S100A3 | SH3D21 | 0.617444 | 6 | 0 | 5 |
| S100A3 | FAM83H | 0.616939 | 6 | 0 | 5 |
| S100A3 | KRTCAP3 | 0.613734 | 3 | 0 | 3 |
| S100A3 | BNC1 | 0.612952 | 9 | 0 | 7 |
| S100A3 | KCNK1 | 0.611874 | 6 | 0 | 3 |
| S100A3 | MTFP1 | 0.609928 | 4 | 0 | 3 |
| S100A3 | ARSJ | 0.608124 | 4 | 0 | 3 |
| S100A3 | PPP1R14C | 0.605472 | 5 | 0 | 3 |
For details and further investigation, click here
