| Full name: mitochondrial fission process 1 | Alias Symbol: MTP18|HSPC242 | ||
| Type: protein-coding gene | Cytoband: 22q12.2 | ||
| Entrez ID: 51537 | HGNC ID: HGNC:26945 | Ensembl Gene: ENSG00000242114 | OMIM ID: 610235 |
| Drug and gene relationship at DGIdb | |||
Expression of MTFP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MTFP1 | 51537 | 223172_s_at | 0.5206 | 0.3459 | |
| GSE26886 | MTFP1 | 51537 | 223172_s_at | 0.5733 | 0.0007 | |
| GSE45670 | MTFP1 | 51537 | 223172_s_at | 0.4782 | 0.0299 | |
| GSE63941 | MTFP1 | 51537 | 223172_s_at | 2.4378 | 0.0000 | |
| GSE77861 | MTFP1 | 51537 | 223172_s_at | 0.0829 | 0.6140 | |
| GSE97050 | MTFP1 | 51537 | A_23_P29204 | 0.6240 | 0.2151 | |
| SRP007169 | MTFP1 | 51537 | RNAseq | 0.8579 | 0.0692 | |
| SRP008496 | MTFP1 | 51537 | RNAseq | 0.4820 | 0.1790 | |
| SRP064894 | MTFP1 | 51537 | RNAseq | 0.7856 | 0.0156 | |
| SRP133303 | MTFP1 | 51537 | RNAseq | 0.6736 | 0.0137 | |
| SRP159526 | MTFP1 | 51537 | RNAseq | 0.4020 | 0.1274 | |
| SRP193095 | MTFP1 | 51537 | RNAseq | 0.2762 | 0.0447 | |
| SRP219564 | MTFP1 | 51537 | RNAseq | 1.0247 | 0.0296 |
Upregulated datasets: 2; Downregulated datasets: 0.
Copy number change of MTFP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MTFP1 | 51537 | 4 | 5 | 21 | |
| GSE20123 | MTFP1 | 51537 | 4 | 4 | 22 | |
| GSE43470 | MTFP1 | 51537 | 4 | 6 | 33 | |
| GSE46452 | MTFP1 | 51537 | 31 | 1 | 27 | |
| GSE47630 | MTFP1 | 51537 | 8 | 5 | 27 | |
| GSE54993 | MTFP1 | 51537 | 3 | 6 | 61 | |
| GSE54994 | MTFP1 | 51537 | 11 | 8 | 34 | |
| GSE60625 | MTFP1 | 51537 | 5 | 0 | 6 | |
| GSE74703 | MTFP1 | 51537 | 4 | 5 | 27 | |
| GSE74704 | MTFP1 | 51537 | 1 | 1 | 18 | |
| TCGA | MTFP1 | 51537 | 27 | 15 | 54 |
Total number of gains: 102; Total number of losses: 56; Total Number of normals: 330.
Somatic mutations of MTFP1:
Generating mutation plots.
Highly correlated genes for MTFP1:
Showing top 20/503 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MTFP1 | GINS3 | 0.793992 | 3 | 0 | 3 |
| MTFP1 | OIP5 | 0.769376 | 4 | 0 | 4 |
| MTFP1 | PKP1 | 0.758157 | 3 | 0 | 3 |
| MTFP1 | TRABD | 0.748208 | 4 | 0 | 4 |
| MTFP1 | EBP | 0.732511 | 3 | 0 | 3 |
| MTFP1 | GPR87 | 0.722146 | 3 | 0 | 3 |
| MTFP1 | GINS4 | 0.721642 | 3 | 0 | 3 |
| MTFP1 | RRM2 | 0.720213 | 4 | 0 | 4 |
| MTFP1 | RAI1 | 0.716495 | 5 | 0 | 5 |
| MTFP1 | CDC20 | 0.714605 | 6 | 0 | 5 |
| MTFP1 | ADORA2B | 0.713492 | 4 | 0 | 4 |
| MTFP1 | TUBAL3 | 0.712272 | 3 | 0 | 3 |
| MTFP1 | GPN1 | 0.709854 | 3 | 0 | 3 |
| MTFP1 | HIP1R | 0.705928 | 3 | 0 | 3 |
| MTFP1 | PMCH | 0.703483 | 3 | 0 | 3 |
| MTFP1 | PLK1 | 0.703212 | 4 | 0 | 4 |
| MTFP1 | LHX1 | 0.699657 | 5 | 0 | 5 |
| MTFP1 | MCM2 | 0.69963 | 5 | 0 | 4 |
| MTFP1 | MAP6D1 | 0.697957 | 3 | 0 | 3 |
| MTFP1 | COG4 | 0.695624 | 3 | 0 | 3 |
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