| Full name: basonuclin 1 | Alias Symbol: HsT19447 | ||
| Type: protein-coding gene | Cytoband: 15q25.2 | ||
| Entrez ID: 646 | HGNC ID: HGNC:1081 | Ensembl Gene: ENSG00000169594 | OMIM ID: 601930 |
| Drug and gene relationship at DGIdb | |||
Expression of BNC1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | BNC1 | 646 | 1552487_a_at | 1.1470 | 0.3636 | |
| GSE20347 | BNC1 | 646 | 206581_at | 0.6037 | 0.0313 | |
| GSE23400 | BNC1 | 646 | 206581_at | 0.4301 | 0.0001 | |
| GSE26886 | BNC1 | 646 | 1552487_a_at | 0.8868 | 0.0706 | |
| GSE29001 | BNC1 | 646 | 206581_at | 0.8584 | 0.0333 | |
| GSE38129 | BNC1 | 646 | 206581_at | 0.9199 | 0.0075 | |
| GSE45670 | BNC1 | 646 | 1552487_a_at | 1.4763 | 0.0003 | |
| GSE53622 | BNC1 | 646 | 45587 | 1.3295 | 0.0000 | |
| GSE53624 | BNC1 | 646 | 45587 | 0.9627 | 0.0000 | |
| GSE63941 | BNC1 | 646 | 1552487_a_at | 0.4665 | 0.7201 | |
| GSE77861 | BNC1 | 646 | 1552487_a_at | 1.2864 | 0.0187 | |
| GSE97050 | BNC1 | 646 | A_23_P22134 | 1.5079 | 0.1450 | |
| SRP007169 | BNC1 | 646 | RNAseq | 1.2410 | 0.0026 | |
| SRP008496 | BNC1 | 646 | RNAseq | 1.1624 | 0.0000 | |
| SRP064894 | BNC1 | 646 | RNAseq | 1.0793 | 0.0102 | |
| SRP133303 | BNC1 | 646 | RNAseq | 1.4758 | 0.0002 | |
| SRP159526 | BNC1 | 646 | RNAseq | 0.8759 | 0.0317 | |
| SRP219564 | BNC1 | 646 | RNAseq | 0.7309 | 0.5079 | |
| TCGA | BNC1 | 646 | RNAseq | 1.8515 | 0.0000 |
Upregulated datasets: 8; Downregulated datasets: 0.
Survival by BNC1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of BNC1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | BNC1 | 646 | 7 | 1 | 22 | |
| GSE20123 | BNC1 | 646 | 7 | 1 | 22 | |
| GSE43470 | BNC1 | 646 | 4 | 4 | 35 | |
| GSE46452 | BNC1 | 646 | 3 | 7 | 49 | |
| GSE47630 | BNC1 | 646 | 8 | 10 | 22 | |
| GSE54993 | BNC1 | 646 | 5 | 6 | 59 | |
| GSE54994 | BNC1 | 646 | 6 | 6 | 41 | |
| GSE60625 | BNC1 | 646 | 4 | 0 | 7 | |
| GSE74703 | BNC1 | 646 | 4 | 2 | 30 | |
| GSE74704 | BNC1 | 646 | 3 | 1 | 16 | |
| TCGA | BNC1 | 646 | 16 | 14 | 66 |
Total number of gains: 67; Total number of losses: 52; Total Number of normals: 369.
Somatic mutations of BNC1:
Generating mutation plots.
Highly correlated genes for BNC1:
Showing top 20/1078 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| BNC1 | IPO4 | 0.730783 | 4 | 0 | 3 |
| BNC1 | CDH3 | 0.714593 | 10 | 0 | 10 |
| BNC1 | GINS4 | 0.704952 | 4 | 0 | 4 |
| BNC1 | FERMT1 | 0.704733 | 10 | 0 | 8 |
| BNC1 | KRT14 | 0.701506 | 13 | 0 | 13 |
| BNC1 | SLC2A1 | 0.697114 | 12 | 0 | 12 |
| BNC1 | TENM2 | 0.694768 | 5 | 0 | 5 |
| BNC1 | DCBLD1 | 0.694346 | 7 | 0 | 6 |
| BNC1 | KRT17 | 0.691235 | 4 | 0 | 3 |
| BNC1 | EME1 | 0.691057 | 5 | 0 | 5 |
| BNC1 | REEP4 | 0.687402 | 4 | 0 | 4 |
| BNC1 | BLACAT1 | 0.686579 | 3 | 0 | 3 |
| BNC1 | AP1G2 | 0.685016 | 3 | 0 | 3 |
| BNC1 | DUSP7 | 0.680798 | 12 | 0 | 9 |
| BNC1 | BRAT1 | 0.677773 | 4 | 0 | 3 |
| BNC1 | NUF2 | 0.677471 | 5 | 0 | 5 |
| BNC1 | C6orf141 | 0.675791 | 5 | 0 | 4 |
| BNC1 | STON2 | 0.674013 | 7 | 0 | 5 |
| BNC1 | GJB3 | 0.67299 | 9 | 0 | 8 |
| BNC1 | AJUBA | 0.67223 | 6 | 0 | 6 |
For details and further investigation, click here
