CYB5R2

 

Full name: cytochrome b5 reductase 2 Alias Symbol: 
Type: protein-coding gene Cytoband: 11p15.4
Entrez ID: 51700 HGNC ID: HGNC:24376 Ensembl Gene: ENSG00000166394 OMIM ID: 608342
Drug and gene relationship at DGIdb

 

Expression of CYB5R2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 CYB5R2 51700 220230_s_at -0.0619 0.9656
GSE20347 CYB5R2 51700 220230_s_at -0.3028 0.2903
GSE23400 CYB5R2 51700 220230_s_at 0.2125 0.0843
GSE26886 CYB5R2 51700 220230_s_at 0.3862 0.2693
GSE29001 CYB5R2 51700 220230_s_at -0.5168 0.0889
GSE38129 CYB5R2 51700 220230_s_at 0.2070 0.5302
GSE45670 CYB5R2 51700 220230_s_at 0.4063 0.3659
GSE53622 CYB5R2 51700 174554 0.6480 0.0004
GSE53624 CYB5R2 51700 174554 0.2019 0.0685
GSE63941 CYB5R2 51700 220230_s_at 0.2446 0.8656
GSE77861 CYB5R2 51700 220230_s_at 0.6159 0.3913
GSE97050 CYB5R2 51700 A_33_P3381265 0.8766 0.2144
SRP007169 CYB5R2 51700 RNAseq 0.2976 0.4147
SRP008496 CYB5R2 51700 RNAseq 0.2040 0.5214
SRP064894 CYB5R2 51700 RNAseq -0.2518 0.4986
SRP133303 CYB5R2 51700 RNAseq 0.4011 0.3699
SRP159526 CYB5R2 51700 RNAseq 0.7188 0.0401
SRP193095 CYB5R2 51700 RNAseq 0.2657 0.2574
SRP219564 CYB5R2 51700 RNAseq 0.2277 0.6931
TCGA CYB5R2 51700 RNAseq 0.7190 0.0000

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by CYB5R2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of CYB5R2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 CYB5R2 51700 0 11 19
GSE20123 CYB5R2 51700 0 11 19
GSE43470 CYB5R2 51700 1 7 35
GSE46452 CYB5R2 51700 7 8 44
GSE47630 CYB5R2 51700 2 12 26
GSE54993 CYB5R2 51700 3 1 66
GSE54994 CYB5R2 51700 2 12 39
GSE60625 CYB5R2 51700 0 0 11
GSE74703 CYB5R2 51700 1 5 30
GSE74704 CYB5R2 51700 0 9 11
TCGA CYB5R2 51700 9 37 50

Total number of gains: 25; Total number of losses: 113; Total Number of normals: 350.  

 

Somatic mutations of CYB5R2:

 

Generating mutation plots.

 

Highly correlated genes for CYB5R2:

 

Showing top 20/176 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
CYB5R2GRHL20.715324303
CYB5R2LGALSL0.688902303
CYB5R2DUSP110.687498505
CYB5R2KRT160.675719404
CYB5R2SH3D210.662422403
CYB5R2ADK0.652357403
CYB5R2SLC11A20.652158404
CYB5R2IPPK0.642925303
CYB5R2S100A30.641293503
CYB5R2RCOR10.633318303
CYB5R2TGFA0.626386403
CYB5R2KRT50.618069504
CYB5R2CHAC20.615972403
CYB5R2ANXA20.615215604
CYB5R2KRT6B0.612569605
CYB5R2FDPS0.61129403
CYB5R2KRT140.610121604
CYB5R2MRPL230.608522404
CYB5R2CYCS0.606628303
CYB5R2DUOXA10.606462403

For details and further investigation, click here