| Full name: SH3 domain containing 21 | Alias Symbol: FLJ22938 | ||
| Type: protein-coding gene | Cytoband: 1p34.3 | ||
| Entrez ID: 79729 | HGNC ID: HGNC:26236 | Ensembl Gene: ENSG00000214193 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of SH3D21:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SH3D21 | 79729 | 220193_at | -0.1331 | 0.8381 | |
| GSE20347 | SH3D21 | 79729 | 220193_at | -0.1096 | 0.1740 | |
| GSE23400 | SH3D21 | 79729 | 220193_at | -0.0487 | 0.1998 | |
| GSE26886 | SH3D21 | 79729 | 220193_at | 0.0770 | 0.6747 | |
| GSE29001 | SH3D21 | 79729 | 220193_at | -0.4391 | 0.0221 | |
| GSE38129 | SH3D21 | 79729 | 220193_at | -0.1418 | 0.0841 | |
| GSE45670 | SH3D21 | 79729 | 220193_at | 0.0758 | 0.6262 | |
| GSE53622 | SH3D21 | 79729 | 74999 | 0.3253 | 0.0619 | |
| GSE53624 | SH3D21 | 79729 | 46970 | 0.0760 | 0.3545 | |
| GSE63941 | SH3D21 | 79729 | 220193_at | 0.2470 | 0.1508 | |
| GSE77861 | SH3D21 | 79729 | 220193_at | -0.0593 | 0.8159 | |
| GSE97050 | SH3D21 | 79729 | A_33_P3250356 | 0.7122 | 0.2306 | |
| SRP007169 | SH3D21 | 79729 | RNAseq | -0.3898 | 0.4782 | |
| SRP064894 | SH3D21 | 79729 | RNAseq | 0.0563 | 0.8710 | |
| SRP133303 | SH3D21 | 79729 | RNAseq | 0.3729 | 0.1613 | |
| SRP159526 | SH3D21 | 79729 | RNAseq | 0.1590 | 0.7360 | |
| SRP193095 | SH3D21 | 79729 | RNAseq | 0.3199 | 0.2081 | |
| SRP219564 | SH3D21 | 79729 | RNAseq | -0.2395 | 0.7772 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SH3D21 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of SH3D21:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SH3D21 | 79729 | 3 | 5 | 22 | |
| GSE20123 | SH3D21 | 79729 | 3 | 4 | 23 | |
| GSE43470 | SH3D21 | 79729 | 7 | 2 | 34 | |
| GSE46452 | SH3D21 | 79729 | 4 | 1 | 54 | |
| GSE47630 | SH3D21 | 79729 | 8 | 3 | 29 | |
| GSE54993 | SH3D21 | 79729 | 1 | 1 | 68 | |
| GSE54994 | SH3D21 | 79729 | 11 | 2 | 40 | |
| GSE60625 | SH3D21 | 79729 | 0 | 0 | 11 | |
| GSE74703 | SH3D21 | 79729 | 6 | 1 | 29 | |
| GSE74704 | SH3D21 | 79729 | 2 | 0 | 18 | |
| TCGA | SH3D21 | 79729 | 11 | 18 | 67 |
Total number of gains: 56; Total number of losses: 37; Total Number of normals: 395.
Somatic mutations of SH3D21:
Generating mutation plots.
Highly correlated genes for SH3D21:
Showing top 20/365 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SH3D21 | KLK5 | 0.692247 | 4 | 0 | 4 |
| SH3D21 | SAMD10 | 0.677032 | 3 | 0 | 3 |
| SH3D21 | PERP | 0.674861 | 3 | 0 | 3 |
| SH3D21 | PPP1R14C | 0.664254 | 3 | 0 | 3 |
| SH3D21 | SCRIB | 0.664086 | 3 | 0 | 3 |
| SH3D21 | CYB5R2 | 0.662422 | 4 | 0 | 3 |
| SH3D21 | USP43 | 0.653455 | 3 | 0 | 3 |
| SH3D21 | SPSB3 | 0.652795 | 3 | 0 | 3 |
| SH3D21 | SLC27A4 | 0.648877 | 4 | 0 | 3 |
| SH3D21 | ADCK5 | 0.64558 | 3 | 0 | 3 |
| SH3D21 | SELPLG | 0.643203 | 3 | 0 | 3 |
| SH3D21 | PLA2G4F | 0.64277 | 5 | 0 | 4 |
| SH3D21 | MYOG | 0.639652 | 5 | 0 | 5 |
| SH3D21 | SGPP2 | 0.638021 | 3 | 0 | 3 |
| SH3D21 | MRPS25 | 0.632977 | 3 | 0 | 3 |
| SH3D21 | GJB5 | 0.632782 | 5 | 0 | 4 |
| SH3D21 | WFDC5 | 0.625968 | 4 | 0 | 3 |
| SH3D21 | CAPG | 0.625423 | 5 | 0 | 4 |
| SH3D21 | PYGL | 0.62281 | 4 | 0 | 3 |
| SH3D21 | GPR87 | 0.622212 | 4 | 0 | 3 |
For details and further investigation, click here
