| Full name: NADH:ubiquinone oxidoreductase complex assembly factor 2 | Alias Symbol: B17.2L|MMTN|mimitin | ||
| Type: protein-coding gene | Cytoband: 5q12.1 | ||
| Entrez ID: 91942 | HGNC ID: HGNC:28086 | Ensembl Gene: ENSG00000164182 | OMIM ID: 609653 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of NDUFAF2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NDUFAF2 | 91942 | 228355_s_at | -0.4000 | 0.5183 | |
| GSE26886 | NDUFAF2 | 91942 | 228355_s_at | 0.1576 | 0.5331 | |
| GSE45670 | NDUFAF2 | 91942 | 228355_s_at | -0.2970 | 0.0273 | |
| GSE53622 | NDUFAF2 | 91942 | 33013 | -0.2859 | 0.0001 | |
| GSE53624 | NDUFAF2 | 91942 | 140064 | -0.1005 | 0.0895 | |
| GSE63941 | NDUFAF2 | 91942 | 228355_s_at | -0.2188 | 0.6800 | |
| GSE77861 | NDUFAF2 | 91942 | 228355_s_at | -0.3427 | 0.0921 | |
| GSE97050 | NDUFAF2 | 91942 | A_23_P345942 | -0.3805 | 0.2607 | |
| SRP007169 | NDUFAF2 | 91942 | RNAseq | -0.5484 | 0.2378 | |
| SRP008496 | NDUFAF2 | 91942 | RNAseq | -0.4770 | 0.1391 | |
| SRP064894 | NDUFAF2 | 91942 | RNAseq | -0.2129 | 0.4224 | |
| SRP133303 | NDUFAF2 | 91942 | RNAseq | 0.1247 | 0.4426 | |
| SRP159526 | NDUFAF2 | 91942 | RNAseq | -0.2873 | 0.4477 | |
| SRP193095 | NDUFAF2 | 91942 | RNAseq | -0.5944 | 0.0008 | |
| SRP219564 | NDUFAF2 | 91942 | RNAseq | -0.3933 | 0.2448 | |
| TCGA | NDUFAF2 | 91942 | RNAseq | -0.0919 | 0.2721 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NDUFAF2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NDUFAF2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NDUFAF2 | 91942 | 0 | 13 | 17 | |
| GSE20123 | NDUFAF2 | 91942 | 0 | 13 | 17 | |
| GSE43470 | NDUFAF2 | 91942 | 1 | 12 | 30 | |
| GSE46452 | NDUFAF2 | 91942 | 0 | 28 | 31 | |
| GSE47630 | NDUFAF2 | 91942 | 2 | 17 | 21 | |
| GSE54993 | NDUFAF2 | 91942 | 8 | 1 | 61 | |
| GSE54994 | NDUFAF2 | 91942 | 1 | 19 | 33 | |
| GSE60625 | NDUFAF2 | 91942 | 0 | 0 | 11 | |
| GSE74703 | NDUFAF2 | 91942 | 1 | 9 | 26 | |
| GSE74704 | NDUFAF2 | 91942 | 0 | 6 | 14 | |
| TCGA | NDUFAF2 | 91942 | 5 | 49 | 42 |
Total number of gains: 18; Total number of losses: 167; Total Number of normals: 303.
Somatic mutations of NDUFAF2:
Generating mutation plots.
Highly correlated genes for NDUFAF2:
Showing top 20/227 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NDUFAF2 | ZNF83 | 0.786136 | 3 | 0 | 3 |
| NDUFAF2 | SACM1L | 0.762562 | 3 | 0 | 3 |
| NDUFAF2 | NEK7 | 0.757025 | 3 | 0 | 3 |
| NDUFAF2 | BDH2 | 0.749369 | 3 | 0 | 3 |
| NDUFAF2 | RPL14 | 0.74676 | 3 | 0 | 3 |
| NDUFAF2 | GBE1 | 0.736214 | 3 | 0 | 3 |
| NDUFAF2 | UFL1 | 0.735846 | 3 | 0 | 3 |
| NDUFAF2 | PCNP | 0.730514 | 3 | 0 | 3 |
| NDUFAF2 | VPS37A | 0.721 | 3 | 0 | 3 |
| NDUFAF2 | ZNF613 | 0.71903 | 3 | 0 | 3 |
| NDUFAF2 | OPTN | 0.708685 | 4 | 0 | 3 |
| NDUFAF2 | COPG2 | 0.704107 | 3 | 0 | 3 |
| NDUFAF2 | HMGCS1 | 0.69947 | 3 | 0 | 3 |
| NDUFAF2 | FAM83D | 0.693745 | 3 | 0 | 3 |
| NDUFAF2 | AK4 | 0.690475 | 4 | 0 | 3 |
| NDUFAF2 | FBXL17 | 0.688121 | 4 | 0 | 3 |
| NDUFAF2 | MOCS2 | 0.686451 | 7 | 0 | 6 |
| NDUFAF2 | USP32 | 0.684663 | 3 | 0 | 3 |
| NDUFAF2 | RPLP2 | 0.683716 | 3 | 0 | 3 |
| NDUFAF2 | SLC25A46 | 0.678379 | 5 | 0 | 5 |
For details and further investigation, click here
