| Full name: succinate-CoA ligase GDP-forming beta subunit | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 3p14.1 | ||
| Entrez ID: 8801 | HGNC ID: HGNC:11450 | Ensembl Gene: ENSG00000172340 | OMIM ID: 603922 |
| Drug and gene relationship at DGIdb | |||
Expression of SUCLG2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SUCLG2 | 8801 | 214835_s_at | -0.6817 | 0.0991 | |
| GSE20347 | SUCLG2 | 8801 | 212459_x_at | -1.3081 | 0.0000 | |
| GSE23400 | SUCLG2 | 8801 | 212459_x_at | -0.7852 | 0.0000 | |
| GSE26886 | SUCLG2 | 8801 | 215772_x_at | -2.3529 | 0.0000 | |
| GSE29001 | SUCLG2 | 8801 | 215772_x_at | -1.2536 | 0.0108 | |
| GSE38129 | SUCLG2 | 8801 | 214835_s_at | -1.3622 | 0.0000 | |
| GSE45670 | SUCLG2 | 8801 | 215772_x_at | -1.0775 | 0.0000 | |
| GSE53622 | SUCLG2 | 8801 | 2524 | -0.9361 | 0.0000 | |
| GSE53624 | SUCLG2 | 8801 | 2524 | -1.1172 | 0.0000 | |
| GSE63941 | SUCLG2 | 8801 | 214835_s_at | -1.0386 | 0.1281 | |
| GSE77861 | SUCLG2 | 8801 | 215772_x_at | -1.5553 | 0.0004 | |
| GSE97050 | SUCLG2 | 8801 | A_33_P3636590 | -1.0384 | 0.0555 | |
| SRP007169 | SUCLG2 | 8801 | RNAseq | -1.6146 | 0.0000 | |
| SRP008496 | SUCLG2 | 8801 | RNAseq | -1.5734 | 0.0000 | |
| SRP064894 | SUCLG2 | 8801 | RNAseq | -0.8698 | 0.0000 | |
| SRP133303 | SUCLG2 | 8801 | RNAseq | -0.8368 | 0.0000 | |
| SRP159526 | SUCLG2 | 8801 | RNAseq | -1.1554 | 0.0014 | |
| SRP193095 | SUCLG2 | 8801 | RNAseq | -1.3806 | 0.0000 | |
| SRP219564 | SUCLG2 | 8801 | RNAseq | -0.9706 | 0.0047 | |
| TCGA | SUCLG2 | 8801 | RNAseq | -0.6560 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 11.
Survival by SUCLG2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SUCLG2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SUCLG2 | 8801 | 1 | 18 | 11 | |
| GSE20123 | SUCLG2 | 8801 | 1 | 18 | 11 | |
| GSE43470 | SUCLG2 | 8801 | 0 | 20 | 23 | |
| GSE46452 | SUCLG2 | 8801 | 2 | 17 | 40 | |
| GSE47630 | SUCLG2 | 8801 | 1 | 23 | 16 | |
| GSE54993 | SUCLG2 | 8801 | 6 | 2 | 62 | |
| GSE54994 | SUCLG2 | 8801 | 1 | 33 | 19 | |
| GSE60625 | SUCLG2 | 8801 | 3 | 1 | 7 | |
| GSE74703 | SUCLG2 | 8801 | 0 | 16 | 20 | |
| GSE74704 | SUCLG2 | 8801 | 1 | 12 | 7 | |
| TCGA | SUCLG2 | 8801 | 0 | 78 | 18 |
Total number of gains: 16; Total number of losses: 238; Total Number of normals: 234.
Somatic mutations of SUCLG2:
Generating mutation plots.
Highly correlated genes for SUCLG2:
Showing top 20/1833 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SUCLG2 | HDHD2 | 0.805462 | 5 | 0 | 5 |
| SUCLG2 | GPD1L | 0.798201 | 12 | 0 | 11 |
| SUCLG2 | AK3 | 0.792435 | 7 | 0 | 7 |
| SUCLG2 | CLEC3B | 0.785867 | 3 | 0 | 3 |
| SUCLG2 | DENND2C | 0.784815 | 3 | 0 | 3 |
| SUCLG2 | MPC1 | 0.78454 | 10 | 0 | 10 |
| SUCLG2 | MPP7 | 0.774148 | 7 | 0 | 7 |
| SUCLG2 | SNORA68 | 0.773312 | 4 | 0 | 4 |
| SUCLG2 | EIF4E3 | 0.762799 | 8 | 0 | 7 |
| SUCLG2 | HPGD | 0.753115 | 11 | 0 | 11 |
| SUCLG2 | ARL6IP5 | 0.751314 | 13 | 0 | 12 |
| SUCLG2 | THOC7 | 0.750838 | 12 | 0 | 12 |
| SUCLG2 | RAP1A | 0.750413 | 11 | 0 | 11 |
| SUCLG2 | RNPC3 | 0.748932 | 4 | 0 | 4 |
| SUCLG2 | PDHB | 0.747394 | 13 | 0 | 13 |
| SUCLG2 | CLDND1 | 0.744309 | 3 | 0 | 3 |
| SUCLG2 | NFIA | 0.74406 | 8 | 0 | 7 |
| SUCLG2 | C12orf29 | 0.743382 | 11 | 0 | 11 |
| SUCLG2 | LRRFIP2 | 0.742815 | 11 | 0 | 11 |
| SUCLG2 | PLEKHA7 | 0.740923 | 7 | 0 | 7 |
For details and further investigation, click here
