| Full name: SR-related CTD associated factor 11 | Alias Symbol: SIP1|SRRP129|CASP11 | ||
| Type: protein-coding gene | Cytoband: 12q12 | ||
| Entrez ID: 9169 | HGNC ID: HGNC:10784 | Ensembl Gene: ENSG00000139218 | OMIM ID: 603668 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of SCAF11:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SCAF11 | 9169 | 206989_s_at | -0.3102 | 0.4473 | |
| GSE20347 | SCAF11 | 9169 | 206989_s_at | -0.2803 | 0.0271 | |
| GSE23400 | SCAF11 | 9169 | 213850_s_at | -0.0068 | 0.9624 | |
| GSE26886 | SCAF11 | 9169 | 225336_at | -0.0332 | 0.9004 | |
| GSE29001 | SCAF11 | 9169 | 213850_s_at | 0.0405 | 0.9404 | |
| GSE38129 | SCAF11 | 9169 | 206989_s_at | -0.0680 | 0.6724 | |
| GSE45670 | SCAF11 | 9169 | 225336_at | -0.1507 | 0.1905 | |
| GSE53622 | SCAF11 | 9169 | 30826 | 0.0068 | 0.8965 | |
| GSE53624 | SCAF11 | 9169 | 95192 | -0.0779 | 0.1677 | |
| GSE63941 | SCAF11 | 9169 | 206989_s_at | -0.1512 | 0.6862 | |
| GSE77861 | SCAF11 | 9169 | 225336_at | 0.2241 | 0.3391 | |
| GSE97050 | SCAF11 | 9169 | A_33_P3219469 | -0.1798 | 0.4124 | |
| SRP007169 | SCAF11 | 9169 | RNAseq | 1.8794 | 0.0145 | |
| SRP008496 | SCAF11 | 9169 | RNAseq | 0.0038 | 0.9826 | |
| SRP064894 | SCAF11 | 9169 | RNAseq | -0.1638 | 0.5163 | |
| SRP133303 | SCAF11 | 9169 | RNAseq | 0.1378 | 0.1811 | |
| SRP159526 | SCAF11 | 9169 | RNAseq | -0.2491 | 0.3067 | |
| SRP193095 | SCAF11 | 9169 | RNAseq | -0.1384 | 0.0801 | |
| SRP219564 | SCAF11 | 9169 | RNAseq | -0.0825 | 0.7317 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by SCAF11 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of SCAF11:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SCAF11 | 9169 | 6 | 1 | 23 | |
| GSE20123 | SCAF11 | 9169 | 6 | 1 | 23 | |
| GSE43470 | SCAF11 | 9169 | 3 | 1 | 39 | |
| GSE46452 | SCAF11 | 9169 | 8 | 1 | 50 | |
| GSE47630 | SCAF11 | 9169 | 11 | 2 | 27 | |
| GSE54993 | SCAF11 | 9169 | 0 | 5 | 65 | |
| GSE54994 | SCAF11 | 9169 | 7 | 1 | 45 | |
| GSE60625 | SCAF11 | 9169 | 0 | 0 | 11 | |
| GSE74703 | SCAF11 | 9169 | 3 | 1 | 32 | |
| GSE74704 | SCAF11 | 9169 | 3 | 1 | 16 | |
| TCGA | SCAF11 | 9169 | 16 | 13 | 67 |
Total number of gains: 63; Total number of losses: 27; Total Number of normals: 398.
Somatic mutations of SCAF11:
Generating mutation plots.
Highly correlated genes for SCAF11:
Showing top 20/272 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SCAF11 | VPS36 | 0.746075 | 3 | 0 | 3 |
| SCAF11 | MTPAP | 0.74261 | 3 | 0 | 3 |
| SCAF11 | SCAMP1 | 0.740677 | 3 | 0 | 3 |
| SCAF11 | NIPSNAP3A | 0.74042 | 3 | 0 | 3 |
| SCAF11 | TBCK | 0.733751 | 3 | 0 | 3 |
| SCAF11 | EP300 | 0.727726 | 3 | 0 | 3 |
| SCAF11 | REPS1 | 0.725572 | 3 | 0 | 3 |
| SCAF11 | MORC4 | 0.72314 | 3 | 0 | 3 |
| SCAF11 | LRRC47 | 0.718475 | 3 | 0 | 3 |
| SCAF11 | MMGT1 | 0.709197 | 3 | 0 | 3 |
| SCAF11 | UBXN4 | 0.70534 | 5 | 0 | 4 |
| SCAF11 | RAB9A | 0.699881 | 3 | 0 | 3 |
| SCAF11 | ZNF398 | 0.699201 | 4 | 0 | 3 |
| SCAF11 | GABPA | 0.691784 | 4 | 0 | 3 |
| SCAF11 | TAF7 | 0.691349 | 3 | 0 | 3 |
| SCAF11 | ING2 | 0.691336 | 4 | 0 | 3 |
| SCAF11 | CRK | 0.689769 | 3 | 0 | 3 |
| SCAF11 | NCBP1 | 0.68356 | 3 | 0 | 3 |
| SCAF11 | APPL1 | 0.682872 | 4 | 0 | 3 |
| SCAF11 | DNAJB14 | 0.679306 | 6 | 0 | 6 |
For details and further investigation, click here
