| Full name: nuclear cap binding protein subunit 1 | Alias Symbol: CBP80|Sto1 | ||
| Type: protein-coding gene | Cytoband: 9q22.33 | ||
| Entrez ID: 4686 | HGNC ID: HGNC:7658 | Ensembl Gene: ENSG00000136937 | OMIM ID: 600469 |
| Drug and gene relationship at DGIdb | |||
Expression of NCBP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NCBP1 | 4686 | 209520_s_at | 0.3404 | 0.3314 | |
| GSE20347 | NCBP1 | 4686 | 209520_s_at | 0.5554 | 0.0318 | |
| GSE23400 | NCBP1 | 4686 | 209520_s_at | 0.5810 | 0.0000 | |
| GSE26886 | NCBP1 | 4686 | 209520_s_at | 0.1412 | 0.5559 | |
| GSE29001 | NCBP1 | 4686 | 209520_s_at | 0.7300 | 0.1696 | |
| GSE38129 | NCBP1 | 4686 | 209520_s_at | 0.8620 | 0.0000 | |
| GSE45670 | NCBP1 | 4686 | 209520_s_at | 0.8312 | 0.0000 | |
| GSE53622 | NCBP1 | 4686 | 63583 | 0.2961 | 0.0000 | |
| GSE53624 | NCBP1 | 4686 | 12805 | 0.1453 | 0.0149 | |
| GSE63941 | NCBP1 | 4686 | 209520_s_at | 0.9841 | 0.0270 | |
| GSE77861 | NCBP1 | 4686 | 209520_s_at | 0.2686 | 0.2453 | |
| GSE97050 | NCBP1 | 4686 | A_33_P3261197 | 0.2734 | 0.3968 | |
| SRP007169 | NCBP1 | 4686 | RNAseq | 1.3253 | 0.0003 | |
| SRP008496 | NCBP1 | 4686 | RNAseq | 1.2121 | 0.0000 | |
| SRP064894 | NCBP1 | 4686 | RNAseq | 0.3933 | 0.0320 | |
| SRP133303 | NCBP1 | 4686 | RNAseq | 0.1878 | 0.0186 | |
| SRP159526 | NCBP1 | 4686 | RNAseq | 0.1047 | 0.6034 | |
| SRP193095 | NCBP1 | 4686 | RNAseq | 0.0238 | 0.7599 | |
| SRP219564 | NCBP1 | 4686 | RNAseq | 0.2083 | 0.3058 | |
| TCGA | NCBP1 | 4686 | RNAseq | 0.0979 | 0.0500 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by NCBP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NCBP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NCBP1 | 4686 | 7 | 8 | 15 | |
| GSE20123 | NCBP1 | 4686 | 7 | 7 | 16 | |
| GSE43470 | NCBP1 | 4686 | 6 | 3 | 34 | |
| GSE46452 | NCBP1 | 4686 | 6 | 14 | 39 | |
| GSE47630 | NCBP1 | 4686 | 1 | 17 | 22 | |
| GSE54993 | NCBP1 | 4686 | 3 | 3 | 64 | |
| GSE54994 | NCBP1 | 4686 | 8 | 11 | 34 | |
| GSE60625 | NCBP1 | 4686 | 0 | 0 | 11 | |
| GSE74703 | NCBP1 | 4686 | 5 | 3 | 28 | |
| GSE74704 | NCBP1 | 4686 | 3 | 5 | 12 | |
| TCGA | NCBP1 | 4686 | 27 | 22 | 47 |
Total number of gains: 73; Total number of losses: 93; Total Number of normals: 322.
Somatic mutations of NCBP1:
Generating mutation plots.
Highly correlated genes for NCBP1:
Showing top 20/1351 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NCBP1 | RNF149 | 0.794464 | 4 | 0 | 4 |
| NCBP1 | TRUB1 | 0.784724 | 3 | 0 | 3 |
| NCBP1 | PDE8A | 0.782587 | 3 | 0 | 3 |
| NCBP1 | TMEM117 | 0.777009 | 3 | 0 | 3 |
| NCBP1 | PPP1R9B | 0.772423 | 3 | 0 | 3 |
| NCBP1 | CPSF3 | 0.736343 | 4 | 0 | 4 |
| NCBP1 | EMG1 | 0.73533 | 7 | 0 | 7 |
| NCBP1 | ACAP2 | 0.732863 | 3 | 0 | 3 |
| NCBP1 | PTPMT1 | 0.730925 | 3 | 0 | 3 |
| NCBP1 | FAM199X | 0.73 | 3 | 0 | 3 |
| NCBP1 | NUB1 | 0.721525 | 3 | 0 | 3 |
| NCBP1 | TOR1B | 0.71643 | 9 | 0 | 8 |
| NCBP1 | TRIM59 | 0.715944 | 4 | 0 | 3 |
| NCBP1 | COMMD2 | 0.712305 | 4 | 0 | 3 |
| NCBP1 | ACP1 | 0.709861 | 8 | 0 | 7 |
| NCBP1 | SMC2 | 0.708507 | 11 | 0 | 9 |
| NCBP1 | PHKA1 | 0.708464 | 3 | 0 | 3 |
| NCBP1 | C1orf56 | 0.707995 | 3 | 0 | 3 |
| NCBP1 | MRPL42 | 0.705808 | 9 | 0 | 8 |
| NCBP1 | SLC25A13 | 0.704766 | 7 | 0 | 7 |
For details and further investigation, click here
