| Full name: GA binding protein transcription factor subunit alpha | Alias Symbol: E4TF1A|NFT2|NRF2|E4TF1-60|NRF2A | ||
| Type: protein-coding gene | Cytoband: 21q21.3 | ||
| Entrez ID: 2551 | HGNC ID: HGNC:4071 | Ensembl Gene: ENSG00000154727 | OMIM ID: 600609 |
| Drug and gene relationship at DGIdb | |||
Expression of GABPA:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GABPA | 2551 | 227428_at | -0.1136 | 0.8078 | |
| GSE20347 | GABPA | 2551 | 210188_at | 0.0488 | 0.6447 | |
| GSE23400 | GABPA | 2551 | 210188_at | 0.0463 | 0.3654 | |
| GSE26886 | GABPA | 2551 | 227428_at | -1.5290 | 0.0000 | |
| GSE29001 | GABPA | 2551 | 210188_at | -0.0051 | 0.9869 | |
| GSE38129 | GABPA | 2551 | 210188_at | 0.2054 | 0.1118 | |
| GSE45670 | GABPA | 2551 | 227428_at | -0.2831 | 0.1156 | |
| GSE53622 | GABPA | 2551 | 23141 | -0.2878 | 0.0000 | |
| GSE53624 | GABPA | 2551 | 23141 | -0.2551 | 0.0074 | |
| GSE63941 | GABPA | 2551 | 210188_at | 1.0574 | 0.0100 | |
| GSE77861 | GABPA | 2551 | 227428_at | -0.2832 | 0.0987 | |
| GSE97050 | GABPA | 2551 | A_33_P3269588 | -0.1254 | 0.4964 | |
| SRP007169 | GABPA | 2551 | RNAseq | -0.6276 | 0.0768 | |
| SRP008496 | GABPA | 2551 | RNAseq | -0.1277 | 0.5822 | |
| SRP064894 | GABPA | 2551 | RNAseq | -0.0734 | 0.7666 | |
| SRP133303 | GABPA | 2551 | RNAseq | -0.2581 | 0.0835 | |
| SRP159526 | GABPA | 2551 | RNAseq | -0.3584 | 0.1314 | |
| SRP193095 | GABPA | 2551 | RNAseq | -0.4010 | 0.0001 | |
| SRP219564 | GABPA | 2551 | RNAseq | -0.5768 | 0.0438 | |
| TCGA | GABPA | 2551 | RNAseq | -0.0782 | 0.1148 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by GABPA expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GABPA:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GABPA | 2551 | 2 | 11 | 17 | |
| GSE20123 | GABPA | 2551 | 2 | 11 | 17 | |
| GSE43470 | GABPA | 2551 | 2 | 8 | 33 | |
| GSE46452 | GABPA | 2551 | 1 | 21 | 37 | |
| GSE47630 | GABPA | 2551 | 6 | 17 | 17 | |
| GSE54993 | GABPA | 2551 | 9 | 2 | 59 | |
| GSE54994 | GABPA | 2551 | 2 | 8 | 43 | |
| GSE60625 | GABPA | 2551 | 0 | 0 | 11 | |
| GSE74703 | GABPA | 2551 | 2 | 6 | 28 | |
| GSE74704 | GABPA | 2551 | 2 | 7 | 11 | |
| TCGA | GABPA | 2551 | 9 | 38 | 49 |
Total number of gains: 37; Total number of losses: 129; Total Number of normals: 322.
Somatic mutations of GABPA:
Generating mutation plots.
Highly correlated genes for GABPA:
Showing top 20/686 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GABPA | CTCF | 0.767125 | 3 | 0 | 3 |
| GABPA | LMBRD2 | 0.752876 | 3 | 0 | 3 |
| GABPA | ZMAT1 | 0.742058 | 3 | 0 | 3 |
| GABPA | WDR92 | 0.736359 | 3 | 0 | 3 |
| GABPA | SPATA5L1 | 0.734392 | 3 | 0 | 3 |
| GABPA | RHBDD1 | 0.733957 | 3 | 0 | 3 |
| GABPA | APPL1 | 0.729794 | 6 | 0 | 5 |
| GABPA | PRPF38A | 0.729575 | 5 | 0 | 4 |
| GABPA | UBAP1 | 0.728751 | 3 | 0 | 3 |
| GABPA | EXOC4 | 0.72808 | 4 | 0 | 3 |
| GABPA | WDFY3 | 0.720515 | 3 | 0 | 3 |
| GABPA | SHPRH | 0.719791 | 3 | 0 | 3 |
| GABPA | USP19 | 0.718305 | 3 | 0 | 3 |
| GABPA | RAB21 | 0.715152 | 3 | 0 | 3 |
| GABPA | TMED4 | 0.714437 | 3 | 0 | 3 |
| GABPA | DHX35 | 0.713493 | 3 | 0 | 3 |
| GABPA | POLE3 | 0.713423 | 4 | 0 | 4 |
| GABPA | MBLAC2 | 0.713141 | 6 | 0 | 5 |
| GABPA | RNF125 | 0.71304 | 6 | 0 | 6 |
| GABPA | GTF2A1 | 0.711181 | 3 | 0 | 3 |
For details and further investigation, click here
