SCGB1A1

 

Full name: secretoglobin family 1A member 1 Alias Symbol: CC10|CCSP|CC16
Type: protein-coding gene Cytoband: 11q12.3
Entrez ID: 7356 HGNC ID: HGNC:12523 Ensembl Gene: ENSG00000149021 OMIM ID: 192020
Drug and gene relationship at DGIdb

 

Expression of SCGB1A1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 SCGB1A1 7356 205725_at -0.7288 0.8304
GSE20347 SCGB1A1 7356 205725_at -0.8318 0.1339
GSE23400 SCGB1A1 7356 205725_at -0.1584 0.5064
GSE26886 SCGB1A1 7356 205725_at -1.8109 0.0000
GSE29001 SCGB1A1 7356 205725_at -0.5409 0.0490
GSE38129 SCGB1A1 7356 205725_at -0.6466 0.1422
GSE45670 SCGB1A1 7356 205725_at -0.4596 0.6311
GSE53622 SCGB1A1 7356 30280 -0.3162 0.1663
GSE53624 SCGB1A1 7356 30280 -1.0775 0.0000
GSE63941 SCGB1A1 7356 205725_at 1.6011 0.3271
GSE77861 SCGB1A1 7356 205725_at -0.9507 0.0032
GSE97050 SCGB1A1 7356 A_23_P150583 0.4863 0.3850
SRP133303 SCGB1A1 7356 RNAseq -0.3176 0.7219
SRP159526 SCGB1A1 7356 RNAseq -2.9208 0.0358
TCGA SCGB1A1 7356 RNAseq -0.2652 0.8318

Upregulated datasets: 0; Downregulated datasets: 3.  


 

Survival by SCGB1A1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of SCGB1A1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 SCGB1A1 7356 6 5 19
GSE20123 SCGB1A1 7356 6 5 19
GSE43470 SCGB1A1 7356 2 6 35
GSE46452 SCGB1A1 7356 8 4 47
GSE47630 SCGB1A1 7356 3 7 30
GSE54993 SCGB1A1 7356 3 0 67
GSE54994 SCGB1A1 7356 4 5 44
GSE60625 SCGB1A1 7356 0 3 8
GSE74703 SCGB1A1 7356 2 3 31
GSE74704 SCGB1A1 7356 4 3 13
TCGA SCGB1A1 7356 14 11 71

Total number of gains: 52; Total number of losses: 52; Total Number of normals: 384.  


 

Somatic mutations of SCGB1A1:

 

Generating mutation plots.

 

Highly correlated genes for SCGB1A1:

 

Showing top 20/247 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
SCGB1A1PIWIL20.740228303
SCGB1A1PAX80.713114303
SCGB1A1GPAT20.686771303
SCGB1A1NHP20.670881404
SCGB1A1DNAI10.658488303
SCGB1A1ALDH3B10.658296403
SCGB1A1C12orf540.656007403
SCGB1A1PEX10.655074403
SCGB1A1SLC23A30.654191303
SCGB1A1SCN2A0.65372303
SCGB1A1RNF1860.651569303
SCGB1A1CUZD10.650568303
SCGB1A1VSIG10L0.645345403
SCGB1A1RHBG0.643497303
SCGB1A1B3GNT80.639595404
SCGB1A1ADAMTS170.636669403
SCGB1A1ACTL80.636204303
SCGB1A1YIPF10.634859504
SCGB1A1APOM0.634706403
SCGB1A1STX190.631485403

For details and further investigation, click here