| Full name: peroxisomal biogenesis factor 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 7q21.2 | ||
| Entrez ID: 5189 | HGNC ID: HGNC:8850 | Ensembl Gene: ENSG00000127980 | OMIM ID: 602136 |
| Drug and gene relationship at DGIdb | |||
Expression of PEX1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PEX1 | 5189 | 204873_at | 0.0578 | 0.9448 | |
| GSE20347 | PEX1 | 5189 | 204873_at | -0.0302 | 0.8653 | |
| GSE23400 | PEX1 | 5189 | 215023_s_at | -0.0633 | 0.2289 | |
| GSE26886 | PEX1 | 5189 | 215023_s_at | -1.2797 | 0.0000 | |
| GSE29001 | PEX1 | 5189 | 204873_at | -0.0736 | 0.8275 | |
| GSE38129 | PEX1 | 5189 | 204873_at | 0.0367 | 0.8224 | |
| GSE45670 | PEX1 | 5189 | 204873_at | 0.0170 | 0.9496 | |
| GSE53622 | PEX1 | 5189 | 14141 | -0.1226 | 0.2503 | |
| GSE53624 | PEX1 | 5189 | 14141 | -0.3900 | 0.0000 | |
| GSE63941 | PEX1 | 5189 | 204873_at | -0.1801 | 0.7388 | |
| GSE77861 | PEX1 | 5189 | 215023_s_at | -0.1083 | 0.5800 | |
| GSE97050 | PEX1 | 5189 | A_23_P20045 | 0.2017 | 0.5113 | |
| SRP007169 | PEX1 | 5189 | RNAseq | -0.5279 | 0.1575 | |
| SRP008496 | PEX1 | 5189 | RNAseq | -0.0783 | 0.8189 | |
| SRP064894 | PEX1 | 5189 | RNAseq | -0.4357 | 0.0976 | |
| SRP133303 | PEX1 | 5189 | RNAseq | 0.1101 | 0.5175 | |
| SRP159526 | PEX1 | 5189 | RNAseq | -0.0961 | 0.6094 | |
| SRP193095 | PEX1 | 5189 | RNAseq | 0.1009 | 0.5867 | |
| SRP219564 | PEX1 | 5189 | RNAseq | -0.0174 | 0.9677 | |
| TCGA | PEX1 | 5189 | RNAseq | -0.0144 | 0.8626 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by PEX1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PEX1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PEX1 | 5189 | 13 | 0 | 17 | |
| GSE20123 | PEX1 | 5189 | 13 | 0 | 17 | |
| GSE43470 | PEX1 | 5189 | 7 | 1 | 35 | |
| GSE46452 | PEX1 | 5189 | 11 | 0 | 48 | |
| GSE47630 | PEX1 | 5189 | 9 | 2 | 29 | |
| GSE54993 | PEX1 | 5189 | 1 | 9 | 60 | |
| GSE54994 | PEX1 | 5189 | 16 | 2 | 35 | |
| GSE60625 | PEX1 | 5189 | 0 | 0 | 11 | |
| GSE74703 | PEX1 | 5189 | 6 | 1 | 29 | |
| GSE74704 | PEX1 | 5189 | 9 | 0 | 11 | |
| TCGA | PEX1 | 5189 | 56 | 4 | 36 |
Total number of gains: 141; Total number of losses: 19; Total Number of normals: 328.
Somatic mutations of PEX1:
Generating mutation plots.
Highly correlated genes for PEX1:
Showing top 20/63 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PEX1 | RCAN3 | 0.66798 | 3 | 0 | 3 |
| PEX1 | SCGB1A1 | 0.655074 | 4 | 0 | 3 |
| PEX1 | MMAA | 0.653776 | 3 | 0 | 3 |
| PEX1 | UBN2 | 0.641243 | 4 | 0 | 4 |
| PEX1 | TMEM144 | 0.640554 | 3 | 0 | 3 |
| PEX1 | KDM6A | 0.639914 | 5 | 0 | 4 |
| PEX1 | SNX16 | 0.623399 | 4 | 0 | 3 |
| PEX1 | TRAPPC11 | 0.617566 | 5 | 0 | 4 |
| PEX1 | VILL | 0.614543 | 3 | 0 | 3 |
| PEX1 | SHOC2 | 0.613437 | 4 | 0 | 3 |
| PEX1 | DLEU2 | 0.612654 | 3 | 0 | 3 |
| PEX1 | TCAIM | 0.60655 | 4 | 0 | 4 |
| PEX1 | SNX31 | 0.602262 | 4 | 0 | 3 |
| PEX1 | AKR7A3 | 0.601875 | 3 | 0 | 3 |
| PEX1 | LARP4B | 0.599911 | 6 | 0 | 5 |
| PEX1 | POLR3B | 0.599204 | 4 | 0 | 3 |
| PEX1 | RBM48 | 0.596667 | 8 | 0 | 7 |
| PEX1 | ZNF43 | 0.594717 | 5 | 0 | 4 |
| PEX1 | ZNF677 | 0.589949 | 3 | 0 | 3 |
| PEX1 | ZNF430 | 0.586024 | 3 | 0 | 3 |
For details and further investigation, click here
