| Full name: aldehyde dehydrogenase 3 family member B1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 11q13.2 | ||
| Entrez ID: 221 | HGNC ID: HGNC:410 | Ensembl Gene: ENSG00000006534 | OMIM ID: 600466 |
| Drug and gene relationship at DGIdb | |||
Expression of ALDH3B1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ALDH3B1 | 221 | 205640_at | -0.5966 | 0.2168 | |
| GSE20347 | ALDH3B1 | 221 | 211004_s_at | -0.3526 | 0.0000 | |
| GSE23400 | ALDH3B1 | 221 | 211004_s_at | -0.1814 | 0.0004 | |
| GSE26886 | ALDH3B1 | 221 | 205640_at | -0.9076 | 0.0009 | |
| GSE29001 | ALDH3B1 | 221 | 205640_at | -1.0496 | 0.0003 | |
| GSE38129 | ALDH3B1 | 221 | 205640_at | -0.9168 | 0.0000 | |
| GSE45670 | ALDH3B1 | 221 | 1565731_at | 0.1149 | 0.1428 | |
| GSE53622 | ALDH3B1 | 221 | 20445 | -0.6627 | 0.0000 | |
| GSE53624 | ALDH3B1 | 221 | 89713 | -0.7740 | 0.0000 | |
| GSE63941 | ALDH3B1 | 221 | 211004_s_at | 0.3218 | 0.6538 | |
| GSE77861 | ALDH3B1 | 221 | 211004_s_at | -0.0978 | 0.3556 | |
| GSE97050 | ALDH3B1 | 221 | A_33_P3236563 | 0.5856 | 0.2467 | |
| SRP007169 | ALDH3B1 | 221 | RNAseq | -4.1231 | 0.0000 | |
| SRP008496 | ALDH3B1 | 221 | RNAseq | -4.0801 | 0.0000 | |
| SRP064894 | ALDH3B1 | 221 | RNAseq | -1.5671 | 0.0000 | |
| SRP133303 | ALDH3B1 | 221 | RNAseq | -1.5721 | 0.0000 | |
| SRP159526 | ALDH3B1 | 221 | RNAseq | -2.2363 | 0.0000 | |
| SRP193095 | ALDH3B1 | 221 | RNAseq | -1.7443 | 0.0000 | |
| SRP219564 | ALDH3B1 | 221 | RNAseq | 0.1589 | 0.6482 | |
| TCGA | ALDH3B1 | 221 | RNAseq | -0.8418 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 7.
Survival by ALDH3B1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ALDH3B1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ALDH3B1 | 221 | 10 | 3 | 17 | |
| GSE20123 | ALDH3B1 | 221 | 10 | 3 | 17 | |
| GSE43470 | ALDH3B1 | 221 | 6 | 3 | 34 | |
| GSE46452 | ALDH3B1 | 221 | 15 | 3 | 41 | |
| GSE47630 | ALDH3B1 | 221 | 10 | 5 | 25 | |
| GSE54993 | ALDH3B1 | 221 | 3 | 2 | 65 | |
| GSE54994 | ALDH3B1 | 221 | 15 | 4 | 34 | |
| GSE60625 | ALDH3B1 | 221 | 0 | 3 | 8 | |
| GSE74703 | ALDH3B1 | 221 | 4 | 2 | 30 | |
| GSE74704 | ALDH3B1 | 221 | 8 | 1 | 11 | |
| TCGA | ALDH3B1 | 221 | 34 | 9 | 53 |
Total number of gains: 115; Total number of losses: 38; Total Number of normals: 335.
Somatic mutations of ALDH3B1:
Generating mutation plots.
Highly correlated genes for ALDH3B1:
Showing top 20/673 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ALDH3B1 | MAB21L3 | 0.71459 | 3 | 0 | 3 |
| ALDH3B1 | ONECUT3 | 0.708164 | 3 | 0 | 3 |
| ALDH3B1 | DIO3 | 0.706321 | 3 | 0 | 3 |
| ALDH3B1 | GAL3ST2 | 0.702422 | 3 | 0 | 3 |
| ALDH3B1 | PADI1 | 0.694898 | 7 | 0 | 6 |
| ALDH3B1 | CD200R1 | 0.68101 | 4 | 0 | 4 |
| ALDH3B1 | ZNRF1 | 0.675837 | 3 | 0 | 3 |
| ALDH3B1 | UPK1A | 0.671885 | 8 | 0 | 8 |
| ALDH3B1 | SULT2B1 | 0.670325 | 7 | 0 | 7 |
| ALDH3B1 | GCKR | 0.66845 | 9 | 0 | 8 |
| ALDH3B1 | FMN1 | 0.663433 | 4 | 0 | 4 |
| ALDH3B1 | ARHGAP40 | 0.663006 | 3 | 0 | 3 |
| ALDH3B1 | PSCA | 0.6616 | 8 | 0 | 7 |
| ALDH3B1 | ECM1 | 0.660794 | 8 | 0 | 7 |
| ALDH3B1 | EPS8L2 | 0.660227 | 10 | 0 | 9 |
| ALDH3B1 | SLC13A4 | 0.658534 | 10 | 0 | 9 |
| ALDH3B1 | HCG22 | 0.658503 | 5 | 0 | 4 |
| ALDH3B1 | SCGB1A1 | 0.658296 | 4 | 0 | 3 |
| ALDH3B1 | APOL5 | 0.657892 | 5 | 0 | 4 |
| ALDH3B1 | MAPK3 | 0.657586 | 9 | 0 | 7 |
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