| Full name: syntaxin 19 | Alias Symbol: MGC21382 | ||
| Type: protein-coding gene | Cytoband: 3q11.2 | ||
| Entrez ID: 415117 | HGNC ID: HGNC:19300 | Ensembl Gene: ENSG00000178750 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of STX19:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | STX19 | 415117 | 1555173_at | -1.3938 | 0.0559 | |
| GSE26886 | STX19 | 415117 | 1555173_at | -2.3098 | 0.0000 | |
| GSE45670 | STX19 | 415117 | 1555173_at | -0.3660 | 0.4201 | |
| GSE53622 | STX19 | 415117 | 69711 | -0.8920 | 0.0000 | |
| GSE53624 | STX19 | 415117 | 69711 | -1.7164 | 0.0000 | |
| GSE63941 | STX19 | 415117 | 1555173_at | 1.5667 | 0.0268 | |
| GSE77861 | STX19 | 415117 | 1555173_at | -1.7134 | 0.0016 | |
| GSE97050 | STX19 | 415117 | A_33_P3269208 | -0.1923 | 0.3735 | |
| SRP007169 | STX19 | 415117 | RNAseq | -3.1023 | 0.0000 | |
| SRP064894 | STX19 | 415117 | RNAseq | -2.5846 | 0.0000 | |
| SRP133303 | STX19 | 415117 | RNAseq | -1.5518 | 0.0000 | |
| SRP159526 | STX19 | 415117 | RNAseq | -2.3735 | 0.0007 | |
| SRP193095 | STX19 | 415117 | RNAseq | -2.2317 | 0.0000 | |
| SRP219564 | STX19 | 415117 | RNAseq | -3.0909 | 0.0008 | |
| TCGA | STX19 | 415117 | RNAseq | -0.7753 | 0.0069 |
Upregulated datasets: 1; Downregulated datasets: 9.
Survival by STX19 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of STX19:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | STX19 | 415117 | 19 | 1 | 10 | |
| GSE20123 | STX19 | 415117 | 18 | 1 | 11 | |
| GSE43470 | STX19 | 415117 | 8 | 9 | 26 | |
| GSE46452 | STX19 | 415117 | 5 | 15 | 39 | |
| GSE47630 | STX19 | 415117 | 14 | 8 | 18 | |
| GSE54993 | STX19 | 415117 | 4 | 3 | 63 | |
| GSE54994 | STX19 | 415117 | 13 | 16 | 24 | |
| GSE60625 | STX19 | 415117 | 0 | 6 | 5 | |
| GSE74703 | STX19 | 415117 | 7 | 7 | 22 | |
| GSE74704 | STX19 | 415117 | 12 | 1 | 7 | |
| TCGA | STX19 | 415117 | 34 | 37 | 25 |
Total number of gains: 134; Total number of losses: 104; Total Number of normals: 250.
Somatic mutations of STX19:
Generating mutation plots.
Highly correlated genes for STX19:
Showing top 20/1023 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| STX19 | VSIG10L | 0.81266 | 7 | 0 | 7 |
| STX19 | CYP3A7 | 0.811309 | 3 | 0 | 3 |
| STX19 | EPS8L2 | 0.806136 | 7 | 0 | 7 |
| STX19 | SCNN1B | 0.805868 | 7 | 0 | 7 |
| STX19 | RAET1E | 0.799383 | 7 | 0 | 7 |
| STX19 | CRCT1 | 0.793212 | 6 | 0 | 6 |
| STX19 | GALNT12 | 0.790458 | 6 | 0 | 6 |
| STX19 | PRSS2 | 0.789658 | 5 | 0 | 5 |
| STX19 | CES2 | 0.784833 | 5 | 0 | 5 |
| STX19 | SLC16A6 | 0.781352 | 6 | 0 | 6 |
| STX19 | IQCF1 | 0.778138 | 4 | 0 | 4 |
| STX19 | DLG2 | 0.773138 | 5 | 0 | 5 |
| STX19 | ITSN2 | 0.771806 | 6 | 0 | 6 |
| STX19 | UBL3 | 0.769654 | 7 | 0 | 7 |
| STX19 | UPK1A | 0.767331 | 7 | 0 | 7 |
| STX19 | SPAG17 | 0.766534 | 6 | 0 | 5 |
| STX19 | CLCA4 | 0.766343 | 8 | 0 | 7 |
| STX19 | FAM214A | 0.765679 | 6 | 0 | 6 |
| STX19 | CYP2C8 | 0.765663 | 3 | 0 | 3 |
| STX19 | DENND2D | 0.764679 | 6 | 0 | 6 |
For details and further investigation, click here
