SCGB2A2

 

Full name: secretoglobin family 2A member 2 Alias Symbol: UGB2|MGC71974
Type: protein-coding gene Cytoband: 11q12.3
Entrez ID: 4250 HGNC ID: HGNC:7050 Ensembl Gene: ENSG00000110484 OMIM ID: 605562
Drug and gene relationship at DGIdb

 

Expression of SCGB2A2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 SCGB2A2 4250 206378_at -2.0214 0.1885
GSE20347 SCGB2A2 4250 206378_at -0.0366 0.6368
GSE23400 SCGB2A2 4250 206378_at -0.3931 0.0001
GSE26886 SCGB2A2 4250 206378_at -0.0202 0.8072
GSE29001 SCGB2A2 4250 206378_at -0.1094 0.2497
GSE38129 SCGB2A2 4250 206378_at -0.2000 0.0804
GSE45670 SCGB2A2 4250 206378_at -2.1041 0.0048
GSE53622 SCGB2A2 4250 12084 -2.6530 0.0000
GSE53624 SCGB2A2 4250 12084 -2.9821 0.0000
GSE63941 SCGB2A2 4250 206378_at 0.2988 0.7531
GSE77861 SCGB2A2 4250 206378_at -0.0481 0.6128
TCGA SCGB2A2 4250 RNAseq 0.4972 0.8461

Upregulated datasets: 0; Downregulated datasets: 3.  


 

Survival by SCGB2A2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of SCGB2A2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 SCGB2A2 4250 6 4 20
GSE20123 SCGB2A2 4250 6 4 20
GSE43470 SCGB2A2 4250 2 6 35
GSE46452 SCGB2A2 4250 8 4 47
GSE47630 SCGB2A2 4250 3 7 30
GSE54993 SCGB2A2 4250 3 0 67
GSE54994 SCGB2A2 4250 4 5 44
GSE60625 SCGB2A2 4250 0 3 8
GSE74703 SCGB2A2 4250 2 3 31
GSE74704 SCGB2A2 4250 4 3 13
TCGA SCGB2A2 4250 14 10 72

Total number of gains: 52; Total number of losses: 49; Total Number of normals: 387.  


 

Somatic mutations of SCGB2A2:

 

Generating mutation plots.

 

Highly correlated genes for SCGB2A2:

 

Showing top 20/77 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
SCGB2A2C6orf580.846646404
SCGB2A2SCGB3A10.806323404
SCGB2A2BPIFB10.790149404
SCGB2A2BPIFB20.789683504
SCGB2A2TFF30.735914706
SCGB2A2SSTR5-AS10.734384303
SCGB2A2MUC5B0.732064907
SCGB2A2C9orf1520.717706504
SCGB2A2SCGB2A10.703882505
SCGB2A2SCGB1D20.697415907
SCGB2A2AZGP10.694586706
SCGB2A2CHRM10.681289404
SCGB2A2MUC70.678256404
SCGB2A2STATH0.676416606
SCGB2A2TFF10.669202705
SCGB2A2LCN10.667824605
SCGB2A2MSMB0.654711404
SCGB2A2NXPE40.653077604
SCGB2A2TSPAN80.652972605
SCGB2A2GP20.651857504

For details and further investigation, click here