| Full name: tetraspanin 8 | Alias Symbol: CO-029 | ||
| Type: protein-coding gene | Cytoband: 12q21.1 | ||
| Entrez ID: 7103 | HGNC ID: HGNC:11855 | Ensembl Gene: ENSG00000127324 | OMIM ID: 600769 |
| Drug and gene relationship at DGIdb | |||
Expression of TSPAN8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TSPAN8 | 7103 | 203824_at | -2.1630 | 0.1299 | |
| GSE20347 | TSPAN8 | 7103 | 203824_at | -0.3332 | 0.0040 | |
| GSE23400 | TSPAN8 | 7103 | 203824_at | -0.5550 | 0.0010 | |
| GSE26886 | TSPAN8 | 7103 | 203824_at | -0.3354 | 0.3709 | |
| GSE29001 | TSPAN8 | 7103 | 203824_at | 0.2272 | 0.6430 | |
| GSE38129 | TSPAN8 | 7103 | 203824_at | -1.3505 | 0.0015 | |
| GSE45670 | TSPAN8 | 7103 | 203824_at | -2.3152 | 0.0000 | |
| GSE53622 | TSPAN8 | 7103 | 87134 | -2.4443 | 0.0000 | |
| GSE53624 | TSPAN8 | 7103 | 87134 | -3.2061 | 0.0000 | |
| GSE63941 | TSPAN8 | 7103 | 203824_at | 0.9254 | 0.5895 | |
| GSE77861 | TSPAN8 | 7103 | 203824_at | -0.2711 | 0.0414 | |
| GSE97050 | TSPAN8 | 7103 | A_23_P36531 | -0.0759 | 0.7637 | |
| SRP064894 | TSPAN8 | 7103 | RNAseq | -5.4727 | 0.0000 | |
| SRP133303 | TSPAN8 | 7103 | RNAseq | -4.1379 | 0.0000 | |
| SRP159526 | TSPAN8 | 7103 | RNAseq | -1.2271 | 0.0739 | |
| SRP219564 | TSPAN8 | 7103 | RNAseq | -1.1666 | 0.1663 | |
| TCGA | TSPAN8 | 7103 | RNAseq | -2.7926 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 7.
Survival by TSPAN8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TSPAN8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TSPAN8 | 7103 | 4 | 0 | 26 | |
| GSE20123 | TSPAN8 | 7103 | 4 | 0 | 26 | |
| GSE43470 | TSPAN8 | 7103 | 4 | 0 | 39 | |
| GSE46452 | TSPAN8 | 7103 | 9 | 1 | 49 | |
| GSE47630 | TSPAN8 | 7103 | 10 | 1 | 29 | |
| GSE54993 | TSPAN8 | 7103 | 0 | 5 | 65 | |
| GSE54994 | TSPAN8 | 7103 | 8 | 1 | 44 | |
| GSE60625 | TSPAN8 | 7103 | 0 | 0 | 11 | |
| GSE74703 | TSPAN8 | 7103 | 4 | 0 | 32 | |
| GSE74704 | TSPAN8 | 7103 | 3 | 1 | 16 | |
| TCGA | TSPAN8 | 7103 | 22 | 8 | 66 |
Total number of gains: 68; Total number of losses: 17; Total Number of normals: 403.
Somatic mutations of TSPAN8:
Generating mutation plots.
Highly correlated genes for TSPAN8:
Showing top 20/533 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TSPAN8 | BPIFB2 | 0.809969 | 5 | 0 | 5 |
| TSPAN8 | C6orf58 | 0.777046 | 6 | 0 | 5 |
| TSPAN8 | NXPE4 | 0.756383 | 4 | 0 | 4 |
| TSPAN8 | BPIFB1 | 0.74199 | 6 | 0 | 5 |
| TSPAN8 | TOX3 | 0.733356 | 6 | 0 | 6 |
| TSPAN8 | ERBB4 | 0.725399 | 3 | 0 | 3 |
| TSPAN8 | TFF3 | 0.72224 | 8 | 0 | 7 |
| TSPAN8 | CHRM1 | 0.721005 | 5 | 0 | 5 |
| TSPAN8 | ZG16B | 0.718624 | 6 | 0 | 5 |
| TSPAN8 | C9orf152 | 0.699707 | 7 | 0 | 7 |
| TSPAN8 | AZGP1 | 0.699479 | 8 | 0 | 7 |
| TSPAN8 | FAM219B | 0.698081 | 3 | 0 | 3 |
| TSPAN8 | MUC5B | 0.696267 | 8 | 0 | 7 |
| TSPAN8 | SCGB2A1 | 0.689343 | 5 | 0 | 4 |
| TSPAN8 | PLCXD3 | 0.68785 | 4 | 0 | 4 |
| TSPAN8 | NOSTRIN | 0.685773 | 5 | 0 | 4 |
| TSPAN8 | GJB1 | 0.680228 | 3 | 0 | 3 |
| TSPAN8 | FAM107A | 0.671653 | 6 | 0 | 6 |
| TSPAN8 | PCAT18 | 0.669255 | 3 | 0 | 3 |
| TSPAN8 | ACSM3 | 0.660144 | 8 | 0 | 7 |
For details and further investigation, click here
