| Full name: secretoglobin family 2A member 1 | Alias Symbol: UGB3|LPHC|MGC71973 | ||
| Type: protein-coding gene | Cytoband: 11q12.3 | ||
| Entrez ID: 4246 | HGNC ID: HGNC:7051 | Ensembl Gene: ENSG00000124939 | OMIM ID: 604398 |
| Drug and gene relationship at DGIdb | |||
Expression of SCGB2A1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SCGB2A1 | 4246 | 205979_at | -1.6619 | 0.2801 | |
| GSE20347 | SCGB2A1 | 4246 | 205979_at | -0.0279 | 0.7328 | |
| GSE23400 | SCGB2A1 | 4246 | 205979_at | -0.2953 | 0.0000 | |
| GSE26886 | SCGB2A1 | 4246 | 205979_at | 0.1479 | 0.2864 | |
| GSE29001 | SCGB2A1 | 4246 | 205979_at | 0.1733 | 0.3165 | |
| GSE38129 | SCGB2A1 | 4246 | 205979_at | -0.1632 | 0.5825 | |
| GSE45670 | SCGB2A1 | 4246 | 205979_at | -1.4770 | 0.0109 | |
| GSE63941 | SCGB2A1 | 4246 | 205979_at | 0.4989 | 0.7040 | |
| GSE77861 | SCGB2A1 | 4246 | 205979_at | -0.0528 | 0.8594 | |
| TCGA | SCGB2A1 | 4246 | RNAseq | -3.4263 | 0.0038 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by SCGB2A1 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of SCGB2A1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SCGB2A1 | 4246 | 5 | 4 | 21 | |
| GSE20123 | SCGB2A1 | 4246 | 5 | 4 | 21 | |
| GSE43470 | SCGB2A1 | 4246 | 2 | 6 | 35 | |
| GSE46452 | SCGB2A1 | 4246 | 8 | 4 | 47 | |
| GSE47630 | SCGB2A1 | 4246 | 3 | 7 | 30 | |
| GSE54993 | SCGB2A1 | 4246 | 3 | 0 | 67 | |
| GSE54994 | SCGB2A1 | 4246 | 4 | 5 | 44 | |
| GSE60625 | SCGB2A1 | 4246 | 0 | 3 | 8 | |
| GSE74703 | SCGB2A1 | 4246 | 2 | 3 | 31 | |
| GSE74704 | SCGB2A1 | 4246 | 4 | 3 | 13 | |
| TCGA | SCGB2A1 | 4246 | 14 | 10 | 72 |
Total number of gains: 50; Total number of losses: 49; Total Number of normals: 389.
Somatic mutations of SCGB2A1:
Generating mutation plots.
Highly correlated genes for SCGB2A1:
Showing top 20/45 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SCGB2A1 | NKX3-1 | 0.775239 | 3 | 0 | 3 |
| SCGB2A1 | SCGB3A1 | 0.737687 | 3 | 0 | 3 |
| SCGB2A1 | C9orf152 | 0.709686 | 3 | 0 | 3 |
| SCGB2A1 | TFF3 | 0.708098 | 6 | 0 | 4 |
| SCGB2A1 | BPIFB1 | 0.706592 | 4 | 0 | 3 |
| SCGB2A1 | SCGB2A2 | 0.703882 | 5 | 0 | 5 |
| SCGB2A1 | AZGP1 | 0.694683 | 6 | 0 | 5 |
| SCGB2A1 | TSPAN8 | 0.689343 | 5 | 0 | 4 |
| SCGB2A1 | CHRM1 | 0.688164 | 3 | 0 | 3 |
| SCGB2A1 | MUC5B | 0.687706 | 5 | 0 | 3 |
| SCGB2A1 | AQP5 | 0.682141 | 4 | 0 | 3 |
| SCGB2A1 | STATH | 0.677644 | 4 | 0 | 4 |
| SCGB2A1 | GP2 | 0.669486 | 3 | 0 | 3 |
| SCGB2A1 | PTPRN2 | 0.656672 | 4 | 0 | 3 |
| SCGB2A1 | TFF1 | 0.65558 | 5 | 0 | 4 |
| SCGB2A1 | TOX3 | 0.647782 | 4 | 0 | 3 |
| SCGB2A1 | PROM1 | 0.620817 | 6 | 0 | 5 |
| SCGB2A1 | AMPD1 | 0.614853 | 4 | 0 | 3 |
| SCGB2A1 | LGI1 | 0.612486 | 3 | 0 | 3 |
| SCGB2A1 | CFB | 0.588558 | 3 | 0 | 3 |
For details and further investigation, click here
