| Full name: SEC14 like lipid binding 2 | Alias Symbol: TAP|SPF|KIAA1186|KIAA1658|TAP1 | ||
| Type: protein-coding gene | Cytoband: 22q12.2 | ||
| Entrez ID: 23541 | HGNC ID: HGNC:10699 | Ensembl Gene: ENSG00000100003 | OMIM ID: 607558 |
| Drug and gene relationship at DGIdb | |||
Expression of SEC14L2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SEC14L2 | 23541 | 204541_at | -0.3967 | 0.6765 | |
| GSE20347 | SEC14L2 | 23541 | 204541_at | -0.2447 | 0.0348 | |
| GSE23400 | SEC14L2 | 23541 | 204541_at | -0.2143 | 0.0000 | |
| GSE26886 | SEC14L2 | 23541 | 204541_at | -0.0966 | 0.7469 | |
| GSE29001 | SEC14L2 | 23541 | 204541_at | -0.4103 | 0.3353 | |
| GSE38129 | SEC14L2 | 23541 | 204541_at | -0.1308 | 0.2992 | |
| GSE45670 | SEC14L2 | 23541 | 204541_at | -0.1416 | 0.5811 | |
| GSE53622 | SEC14L2 | 23541 | 95237 | -0.2761 | 0.0012 | |
| GSE53624 | SEC14L2 | 23541 | 95237 | -0.2886 | 0.0005 | |
| GSE63941 | SEC14L2 | 23541 | 204541_at | 0.0258 | 0.9728 | |
| GSE77861 | SEC14L2 | 23541 | 204541_at | -0.2186 | 0.3721 | |
| GSE97050 | SEC14L2 | 23541 | A_23_P17811 | 0.1537 | 0.6921 | |
| SRP007169 | SEC14L2 | 23541 | RNAseq | -2.7841 | 0.0000 | |
| SRP008496 | SEC14L2 | 23541 | RNAseq | -1.4408 | 0.0061 | |
| SRP064894 | SEC14L2 | 23541 | RNAseq | -0.6569 | 0.0276 | |
| SRP133303 | SEC14L2 | 23541 | RNAseq | -0.0141 | 0.9727 | |
| SRP159526 | SEC14L2 | 23541 | RNAseq | -1.5969 | 0.0000 | |
| SRP193095 | SEC14L2 | 23541 | RNAseq | -0.8596 | 0.0000 | |
| SRP219564 | SEC14L2 | 23541 | RNAseq | -0.3159 | 0.6752 | |
| TCGA | SEC14L2 | 23541 | RNAseq | 0.1690 | 0.2175 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by SEC14L2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SEC14L2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SEC14L2 | 23541 | 4 | 5 | 21 | |
| GSE20123 | SEC14L2 | 23541 | 4 | 4 | 22 | |
| GSE43470 | SEC14L2 | 23541 | 4 | 6 | 33 | |
| GSE46452 | SEC14L2 | 23541 | 31 | 1 | 27 | |
| GSE47630 | SEC14L2 | 23541 | 8 | 5 | 27 | |
| GSE54993 | SEC14L2 | 23541 | 3 | 6 | 61 | |
| GSE54994 | SEC14L2 | 23541 | 11 | 8 | 34 | |
| GSE60625 | SEC14L2 | 23541 | 5 | 0 | 6 | |
| GSE74703 | SEC14L2 | 23541 | 4 | 5 | 27 | |
| GSE74704 | SEC14L2 | 23541 | 1 | 1 | 18 | |
| TCGA | SEC14L2 | 23541 | 27 | 15 | 54 |
Total number of gains: 102; Total number of losses: 56; Total Number of normals: 330.
Somatic mutations of SEC14L2:
Generating mutation plots.
Highly correlated genes for SEC14L2:
Showing top 20/135 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SEC14L2 | POLR3G | 0.681579 | 3 | 0 | 3 |
| SEC14L2 | SLC16A11 | 0.661562 | 3 | 0 | 3 |
| SEC14L2 | MEGF11 | 0.661142 | 3 | 0 | 3 |
| SEC14L2 | IGFN1 | 0.651372 | 3 | 0 | 3 |
| SEC14L2 | BCL2L10 | 0.645078 | 4 | 0 | 3 |
| SEC14L2 | LCT | 0.642135 | 3 | 0 | 3 |
| SEC14L2 | APOA1 | 0.639062 | 3 | 0 | 3 |
| SEC14L2 | COG4 | 0.63057 | 4 | 0 | 3 |
| SEC14L2 | TEKT2 | 0.625958 | 3 | 0 | 3 |
| SEC14L2 | CYP2D6 | 0.624696 | 3 | 0 | 3 |
| SEC14L2 | CPNE7 | 0.620293 | 4 | 0 | 3 |
| SEC14L2 | CALHM3 | 0.618945 | 3 | 0 | 3 |
| SEC14L2 | GPT | 0.618201 | 4 | 0 | 3 |
| SEC14L2 | CDHR5 | 0.614074 | 3 | 0 | 3 |
| SEC14L2 | BNIP3L | 0.6124 | 4 | 0 | 3 |
| SEC14L2 | C15orf48 | 0.60686 | 4 | 0 | 3 |
| SEC14L2 | FAM9A | 0.597358 | 3 | 0 | 3 |
| SEC14L2 | IGFL1 | 0.596665 | 5 | 0 | 3 |
| SEC14L2 | SPACA3 | 0.596565 | 3 | 0 | 3 |
| SEC14L2 | ZNF821 | 0.596193 | 5 | 0 | 3 |
For details and further investigation, click here
