| Full name: component of oligomeric golgi complex 4 | Alias Symbol: COD1|DKFZP586E1519 | ||
| Type: protein-coding gene | Cytoband: 16q22.1 | ||
| Entrez ID: 25839 | HGNC ID: HGNC:18620 | Ensembl Gene: ENSG00000103051 | OMIM ID: 606976 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of COG4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | COG4 | 25839 | 212189_s_at | 0.1203 | 0.8291 | |
| GSE20347 | COG4 | 25839 | 212189_s_at | -0.2636 | 0.0056 | |
| GSE23400 | COG4 | 25839 | 212189_s_at | -0.2030 | 0.0025 | |
| GSE26886 | COG4 | 25839 | 212189_s_at | -0.1846 | 0.3579 | |
| GSE29001 | COG4 | 25839 | 212189_s_at | -0.3534 | 0.0233 | |
| GSE38129 | COG4 | 25839 | 212189_s_at | -0.0439 | 0.7262 | |
| GSE45670 | COG4 | 25839 | 212189_s_at | 0.1265 | 0.2406 | |
| GSE53622 | COG4 | 25839 | 60426 | 0.0099 | 0.8833 | |
| GSE53624 | COG4 | 25839 | 23058 | -0.3194 | 0.0000 | |
| GSE63941 | COG4 | 25839 | 212189_s_at | 0.5148 | 0.1426 | |
| GSE77861 | COG4 | 25839 | 212189_s_at | -0.1815 | 0.2654 | |
| GSE97050 | COG4 | 25839 | A_33_P3257628 | 0.1465 | 0.5133 | |
| SRP007169 | COG4 | 25839 | RNAseq | -1.1141 | 0.0004 | |
| SRP008496 | COG4 | 25839 | RNAseq | -1.3107 | 0.0000 | |
| SRP064894 | COG4 | 25839 | RNAseq | -0.2204 | 0.1145 | |
| SRP133303 | COG4 | 25839 | RNAseq | -0.0476 | 0.8254 | |
| SRP159526 | COG4 | 25839 | RNAseq | 0.1992 | 0.6452 | |
| SRP193095 | COG4 | 25839 | RNAseq | -0.1170 | 0.3307 | |
| SRP219564 | COG4 | 25839 | RNAseq | -0.3254 | 0.1756 | |
| TCGA | COG4 | 25839 | RNAseq | 0.0622 | 0.2039 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by COG4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of COG4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | COG4 | 25839 | 6 | 1 | 23 | |
| GSE20123 | COG4 | 25839 | 6 | 1 | 23 | |
| GSE43470 | COG4 | 25839 | 2 | 8 | 33 | |
| GSE46452 | COG4 | 25839 | 38 | 1 | 20 | |
| GSE47630 | COG4 | 25839 | 11 | 8 | 21 | |
| GSE54993 | COG4 | 25839 | 2 | 4 | 64 | |
| GSE54994 | COG4 | 25839 | 8 | 10 | 35 | |
| GSE60625 | COG4 | 25839 | 4 | 0 | 7 | |
| GSE74703 | COG4 | 25839 | 2 | 5 | 29 | |
| GSE74704 | COG4 | 25839 | 3 | 0 | 17 | |
| TCGA | COG4 | 25839 | 27 | 12 | 57 |
Total number of gains: 109; Total number of losses: 50; Total Number of normals: 329.
Somatic mutations of COG4:
Generating mutation plots.
Highly correlated genes for COG4:
Showing top 20/148 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| COG4 | GPN2 | 0.73298 | 3 | 0 | 3 |
| COG4 | RAB11FIP4 | 0.70218 | 3 | 0 | 3 |
| COG4 | MTFP1 | 0.695624 | 3 | 0 | 3 |
| COG4 | MFSD6L | 0.683665 | 4 | 0 | 3 |
| COG4 | SERINC5 | 0.681728 | 3 | 0 | 3 |
| COG4 | GLTPD2 | 0.677973 | 3 | 0 | 3 |
| COG4 | D2HGDH | 0.663434 | 3 | 0 | 3 |
| COG4 | PCYOX1L | 0.663169 | 4 | 0 | 3 |
| COG4 | SEC14L2 | 0.63057 | 4 | 0 | 3 |
| COG4 | SMPD3 | 0.629498 | 4 | 0 | 3 |
| COG4 | SEC13 | 0.624666 | 4 | 0 | 3 |
| COG4 | ESPNL | 0.620149 | 3 | 0 | 3 |
| COG4 | TMEM125 | 0.619692 | 4 | 0 | 3 |
| COG4 | COX8A | 0.612098 | 3 | 0 | 3 |
| COG4 | GJA3 | 0.611171 | 4 | 0 | 4 |
| COG4 | SP6 | 0.608088 | 5 | 0 | 4 |
| COG4 | TECR | 0.605719 | 7 | 0 | 7 |
| COG4 | LIPH | 0.603961 | 3 | 0 | 3 |
| COG4 | CARD6 | 0.59775 | 5 | 0 | 4 |
| COG4 | STXBP2 | 0.596804 | 5 | 0 | 3 |
For details and further investigation, click here
