| Full name: BCL2 interacting protein 3 like | Alias Symbol: Nix|BNIP3a | ||
| Type: protein-coding gene | Cytoband: 8p21.2 | ||
| Entrez ID: 665 | HGNC ID: HGNC:1085 | Ensembl Gene: ENSG00000104765 | OMIM ID: 605368 |
| Drug and gene relationship at DGIdb | |||
Expression of BNIP3L:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | BNIP3L | 665 | 221479_s_at | -0.4533 | 0.3214 | |
| GSE20347 | BNIP3L | 665 | 221479_s_at | -0.6772 | 0.0069 | |
| GSE23400 | BNIP3L | 665 | 221479_s_at | -0.3414 | 0.0087 | |
| GSE26886 | BNIP3L | 665 | 221478_at | -0.0492 | 0.8670 | |
| GSE29001 | BNIP3L | 665 | 221478_at | -0.0433 | 0.9182 | |
| GSE38129 | BNIP3L | 665 | 221478_at | -0.2598 | 0.1087 | |
| GSE45670 | BNIP3L | 665 | 221478_at | -0.2364 | 0.2239 | |
| GSE53622 | BNIP3L | 665 | 115228 | -0.0960 | 0.3026 | |
| GSE53624 | BNIP3L | 665 | 115228 | -0.2560 | 0.0000 | |
| GSE63941 | BNIP3L | 665 | 221478_at | -1.9598 | 0.0005 | |
| GSE77861 | BNIP3L | 665 | 221479_s_at | -0.1825 | 0.6608 | |
| GSE97050 | BNIP3L | 665 | A_33_P3268900 | 0.6577 | 0.0871 | |
| SRP007169 | BNIP3L | 665 | RNAseq | -0.4648 | 0.2890 | |
| SRP008496 | BNIP3L | 665 | RNAseq | -0.3300 | 0.3103 | |
| SRP064894 | BNIP3L | 665 | RNAseq | -0.3568 | 0.1073 | |
| SRP133303 | BNIP3L | 665 | RNAseq | -0.0814 | 0.7550 | |
| SRP159526 | BNIP3L | 665 | RNAseq | -0.4135 | 0.0236 | |
| SRP193095 | BNIP3L | 665 | RNAseq | -0.5410 | 0.0030 | |
| SRP219564 | BNIP3L | 665 | RNAseq | -0.5832 | 0.1754 | |
| TCGA | BNIP3L | 665 | RNAseq | 0.0814 | 0.1584 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by BNIP3L expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of BNIP3L:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | BNIP3L | 665 | 4 | 12 | 14 | |
| GSE20123 | BNIP3L | 665 | 4 | 12 | 14 | |
| GSE43470 | BNIP3L | 665 | 4 | 7 | 32 | |
| GSE46452 | BNIP3L | 665 | 13 | 13 | 33 | |
| GSE47630 | BNIP3L | 665 | 10 | 8 | 22 | |
| GSE54993 | BNIP3L | 665 | 2 | 15 | 53 | |
| GSE54994 | BNIP3L | 665 | 9 | 16 | 28 | |
| GSE60625 | BNIP3L | 665 | 3 | 0 | 8 | |
| GSE74703 | BNIP3L | 665 | 4 | 6 | 26 | |
| GSE74704 | BNIP3L | 665 | 3 | 8 | 9 | |
| TCGA | BNIP3L | 665 | 14 | 44 | 38 |
Total number of gains: 70; Total number of losses: 141; Total Number of normals: 277.
Somatic mutations of BNIP3L:
Generating mutation plots.
Highly correlated genes for BNIP3L:
Showing top 20/51 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| BNIP3L | MIR34A | 0.669697 | 3 | 0 | 3 |
| BNIP3L | CABLES1 | 0.652376 | 3 | 0 | 3 |
| BNIP3L | TTC37 | 0.636823 | 5 | 0 | 4 |
| BNIP3L | LIAS | 0.625157 | 3 | 0 | 3 |
| BNIP3L | EMC2 | 0.615798 | 3 | 0 | 3 |
| BNIP3L | SEC14L2 | 0.6124 | 4 | 0 | 3 |
| BNIP3L | NDUFS4 | 0.587543 | 4 | 0 | 3 |
| BNIP3L | DHX29 | 0.586865 | 5 | 0 | 3 |
| BNIP3L | PCM1 | 0.586305 | 8 | 0 | 7 |
| BNIP3L | ITGB5 | 0.586018 | 4 | 0 | 3 |
| BNIP3L | SLC25A46 | 0.582953 | 4 | 0 | 3 |
| BNIP3L | HILPDA | 0.578959 | 6 | 0 | 4 |
| BNIP3L | PALLD | 0.573423 | 4 | 0 | 3 |
| BNIP3L | CLIP1 | 0.572128 | 4 | 0 | 3 |
| BNIP3L | PPP2CB | 0.569038 | 8 | 0 | 6 |
| BNIP3L | ADAM9 | 0.568183 | 4 | 0 | 3 |
| BNIP3L | HOOK3 | 0.565579 | 6 | 0 | 5 |
| BNIP3L | VPS37A | 0.561449 | 6 | 0 | 5 |
| BNIP3L | MON2 | 0.560161 | 5 | 0 | 4 |
| BNIP3L | ATP6V1C2 | 0.555268 | 3 | 0 | 3 |
For details and further investigation, click here
