| Full name: IGF like family member 1 | Alias Symbol: UNQ644 | ||
| Type: protein-coding gene | Cytoband: 19q13.32 | ||
| Entrez ID: 374918 | HGNC ID: HGNC:24093 | Ensembl Gene: ENSG00000188293 | OMIM ID: 610544 |
| Drug and gene relationship at DGIdb | |||
Expression of IGFL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IGFL1 | 374918 | 239430_at | -2.9674 | 0.1515 | |
| GSE26886 | IGFL1 | 374918 | 239430_at | -1.2543 | 0.0437 | |
| GSE45670 | IGFL1 | 374918 | 239430_at | -1.8324 | 0.0175 | |
| GSE53622 | IGFL1 | 374918 | 21682 | -1.7368 | 0.0000 | |
| GSE53624 | IGFL1 | 374918 | 21682 | -2.6491 | 0.0000 | |
| GSE63941 | IGFL1 | 374918 | 239430_at | 0.7136 | 0.3670 | |
| GSE77861 | IGFL1 | 374918 | 239430_at | -1.7151 | 0.0712 | |
| GSE97050 | IGFL1 | 374918 | A_33_P3289845 | -0.0316 | 0.9713 | |
| SRP007169 | IGFL1 | 374918 | RNAseq | -7.3588 | 0.0000 | |
| SRP008496 | IGFL1 | 374918 | RNAseq | -2.4032 | 0.0611 | |
| SRP064894 | IGFL1 | 374918 | RNAseq | -2.8674 | 0.0000 | |
| SRP133303 | IGFL1 | 374918 | RNAseq | -3.1287 | 0.0000 | |
| SRP219564 | IGFL1 | 374918 | RNAseq | -3.0188 | 0.0382 | |
| TCGA | IGFL1 | 374918 | RNAseq | 1.2528 | 0.0090 |
Upregulated datasets: 1; Downregulated datasets: 8.
Survival by IGFL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IGFL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IGFL1 | 374918 | 4 | 5 | 21 | |
| GSE20123 | IGFL1 | 374918 | 4 | 4 | 22 | |
| GSE43470 | IGFL1 | 374918 | 3 | 11 | 29 | |
| GSE46452 | IGFL1 | 374918 | 45 | 1 | 13 | |
| GSE47630 | IGFL1 | 374918 | 8 | 7 | 25 | |
| GSE54993 | IGFL1 | 374918 | 17 | 4 | 49 | |
| GSE54994 | IGFL1 | 374918 | 5 | 13 | 35 | |
| GSE60625 | IGFL1 | 374918 | 9 | 0 | 2 | |
| GSE74703 | IGFL1 | 374918 | 3 | 7 | 26 | |
| GSE74704 | IGFL1 | 374918 | 4 | 2 | 14 | |
| TCGA | IGFL1 | 374918 | 15 | 15 | 66 |
Total number of gains: 117; Total number of losses: 69; Total Number of normals: 302.
Somatic mutations of IGFL1:
Generating mutation plots.
Highly correlated genes for IGFL1:
Showing top 20/749 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IGFL1 | FAM163B | 0.809372 | 3 | 0 | 3 |
| IGFL1 | RNF222 | 0.802947 | 3 | 0 | 3 |
| IGFL1 | NCCRP1 | 0.791317 | 3 | 0 | 3 |
| IGFL1 | MFSD2B | 0.776945 | 3 | 0 | 3 |
| IGFL1 | DND1 | 0.762949 | 3 | 0 | 3 |
| IGFL1 | MALL | 0.754721 | 7 | 0 | 7 |
| IGFL1 | OTOP3 | 0.753961 | 3 | 0 | 3 |
| IGFL1 | CD164L2 | 0.750877 | 3 | 0 | 3 |
| IGFL1 | ACER1 | 0.741597 | 7 | 0 | 7 |
| IGFL1 | HMGB4 | 0.740529 | 4 | 0 | 4 |
| IGFL1 | KCNA7 | 0.739749 | 3 | 0 | 3 |
| IGFL1 | ZNF705G | 0.738821 | 3 | 0 | 3 |
| IGFL1 | HAMP | 0.738047 | 3 | 0 | 3 |
| IGFL1 | TMEM154 | 0.736964 | 6 | 0 | 6 |
| IGFL1 | MUC22 | 0.73647 | 3 | 0 | 3 |
| IGFL1 | NOTO | 0.732557 | 3 | 0 | 3 |
| IGFL1 | ENDOU | 0.731349 | 6 | 0 | 6 |
| IGFL1 | ATG9B | 0.730584 | 6 | 0 | 6 |
| IGFL1 | GPR78 | 0.728707 | 3 | 0 | 3 |
| IGFL1 | RAET1E | 0.726054 | 7 | 0 | 6 |
For details and further investigation, click here
