| Full name: SEC31 homolog B, COPII coat complex component | Alias Symbol: SEC31B-1|DKFZP434M183 | ||
| Type: protein-coding gene | Cytoband: 10q24.31 | ||
| Entrez ID: 25956 | HGNC ID: HGNC:23197 | Ensembl Gene: ENSG00000075826 | OMIM ID: 610258 |
| Drug and gene relationship at DGIdb | |||
Expression of SEC31B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SEC31B | 25956 | 209889_at | -0.4307 | 0.1721 | |
| GSE20347 | SEC31B | 25956 | 209889_at | -0.0632 | 0.6267 | |
| GSE23400 | SEC31B | 25956 | 209889_at | -0.1564 | 0.0063 | |
| GSE26886 | SEC31B | 25956 | 209889_at | -0.2169 | 0.2156 | |
| GSE29001 | SEC31B | 25956 | 209889_at | -0.1025 | 0.7626 | |
| GSE38129 | SEC31B | 25956 | 209889_at | -0.3231 | 0.0078 | |
| GSE45670 | SEC31B | 25956 | 209889_at | -0.1601 | 0.3266 | |
| GSE53622 | SEC31B | 25956 | 52307 | -0.3527 | 0.0027 | |
| GSE53624 | SEC31B | 25956 | 52307 | -0.4287 | 0.0000 | |
| GSE63941 | SEC31B | 25956 | 209889_at | -0.2647 | 0.4874 | |
| GSE77861 | SEC31B | 25956 | 209889_at | -0.1112 | 0.6004 | |
| GSE97050 | SEC31B | 25956 | A_23_P35564 | -0.1102 | 0.6628 | |
| SRP064894 | SEC31B | 25956 | RNAseq | -0.2194 | 0.4060 | |
| SRP133303 | SEC31B | 25956 | RNAseq | -0.4405 | 0.0046 | |
| SRP159526 | SEC31B | 25956 | RNAseq | -0.6030 | 0.0632 | |
| SRP193095 | SEC31B | 25956 | RNAseq | 0.2699 | 0.2122 | |
| SRP219564 | SEC31B | 25956 | RNAseq | -0.2343 | 0.5283 | |
| TCGA | SEC31B | 25956 | RNAseq | -0.4463 | 0.0033 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SEC31B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SEC31B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SEC31B | 25956 | 1 | 8 | 21 | |
| GSE20123 | SEC31B | 25956 | 1 | 7 | 22 | |
| GSE43470 | SEC31B | 25956 | 0 | 8 | 35 | |
| GSE46452 | SEC31B | 25956 | 0 | 11 | 48 | |
| GSE47630 | SEC31B | 25956 | 2 | 14 | 24 | |
| GSE54993 | SEC31B | 25956 | 8 | 0 | 62 | |
| GSE54994 | SEC31B | 25956 | 1 | 12 | 40 | |
| GSE60625 | SEC31B | 25956 | 0 | 0 | 11 | |
| GSE74703 | SEC31B | 25956 | 0 | 5 | 31 | |
| GSE74704 | SEC31B | 25956 | 0 | 4 | 16 | |
| TCGA | SEC31B | 25956 | 5 | 28 | 63 |
Total number of gains: 18; Total number of losses: 97; Total Number of normals: 373.
Somatic mutations of SEC31B:
Generating mutation plots.
Highly correlated genes for SEC31B:
Showing top 20/352 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SEC31B | STAC | 0.770982 | 3 | 0 | 3 |
| SEC31B | GSX1 | 0.763302 | 3 | 0 | 3 |
| SEC31B | ANAPC16 | 0.75596 | 3 | 0 | 3 |
| SEC31B | THSD7A | 0.740946 | 3 | 0 | 3 |
| SEC31B | CCDC3 | 0.734269 | 3 | 0 | 3 |
| SEC31B | RILP | 0.730409 | 3 | 0 | 3 |
| SEC31B | PYROXD2 | 0.718619 | 3 | 0 | 3 |
| SEC31B | ZFYVE9 | 0.718364 | 4 | 0 | 3 |
| SEC31B | RNF214 | 0.716523 | 3 | 0 | 3 |
| SEC31B | THYN1 | 0.716209 | 3 | 0 | 3 |
| SEC31B | TLN2 | 0.712797 | 3 | 0 | 3 |
| SEC31B | EMD | 0.70899 | 3 | 0 | 3 |
| SEC31B | YPEL2 | 0.706361 | 3 | 0 | 3 |
| SEC31B | DNAJC27 | 0.705566 | 3 | 0 | 3 |
| SEC31B | CELF6 | 0.704784 | 3 | 0 | 3 |
| SEC31B | ZDHHC11 | 0.703659 | 3 | 0 | 3 |
| SEC31B | WDR59 | 0.700843 | 3 | 0 | 3 |
| SEC31B | GALNT11 | 0.694326 | 3 | 0 | 3 |
| SEC31B | CYYR1 | 0.693185 | 3 | 0 | 3 |
| SEC31B | ADAMTS10 | 0.691951 | 3 | 0 | 3 |
For details and further investigation, click here
