| Full name: thrombospondin type 1 domain containing 7A | Alias Symbol: KIAA0960 | ||
| Type: protein-coding gene | Cytoband: 7p21.3 | ||
| Entrez ID: 221981 | HGNC ID: HGNC:22207 | Ensembl Gene: ENSG00000005108 | OMIM ID: 612249 |
| Drug and gene relationship at DGIdb | |||
Expression of THSD7A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | THSD7A | 221981 | 213894_at | -0.6919 | 0.1534 | |
| GSE20347 | THSD7A | 221981 | 214920_at | -0.2021 | 0.0311 | |
| GSE23400 | THSD7A | 221981 | 213894_at | 0.0727 | 0.1678 | |
| GSE26886 | THSD7A | 221981 | 230008_at | -0.2082 | 0.1305 | |
| GSE29001 | THSD7A | 221981 | 214920_at | -0.4218 | 0.0809 | |
| GSE38129 | THSD7A | 221981 | 214920_at | -0.4271 | 0.0482 | |
| GSE45670 | THSD7A | 221981 | 230008_at | -0.7132 | 0.0371 | |
| GSE53622 | THSD7A | 221981 | 39867 | -0.9426 | 0.0000 | |
| GSE53624 | THSD7A | 221981 | 39867 | -0.8311 | 0.0000 | |
| GSE63941 | THSD7A | 221981 | 230008_at | -0.2838 | 0.0851 | |
| GSE77861 | THSD7A | 221981 | 230008_at | 0.0207 | 0.9321 | |
| GSE97050 | THSD7A | 221981 | A_24_P400324 | -0.0066 | 0.9884 | |
| SRP007169 | THSD7A | 221981 | RNAseq | 2.2517 | 0.0018 | |
| SRP133303 | THSD7A | 221981 | RNAseq | -0.6984 | 0.0004 | |
| SRP159526 | THSD7A | 221981 | RNAseq | -0.2794 | 0.6261 | |
| SRP193095 | THSD7A | 221981 | RNAseq | 0.3229 | 0.1862 | |
| SRP219564 | THSD7A | 221981 | RNAseq | 0.2312 | 0.7446 | |
| TCGA | THSD7A | 221981 | RNAseq | -0.9477 | 0.0032 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by THSD7A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of THSD7A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | THSD7A | 221981 | 14 | 2 | 14 | |
| GSE20123 | THSD7A | 221981 | 14 | 2 | 14 | |
| GSE43470 | THSD7A | 221981 | 5 | 0 | 38 | |
| GSE46452 | THSD7A | 221981 | 11 | 1 | 47 | |
| GSE47630 | THSD7A | 221981 | 9 | 1 | 30 | |
| GSE54993 | THSD7A | 221981 | 0 | 6 | 64 | |
| GSE54994 | THSD7A | 221981 | 22 | 1 | 30 | |
| GSE60625 | THSD7A | 221981 | 0 | 0 | 11 | |
| GSE74703 | THSD7A | 221981 | 5 | 0 | 31 | |
| GSE74704 | THSD7A | 221981 | 8 | 2 | 10 | |
| TCGA | THSD7A | 221981 | 54 | 7 | 35 |
Total number of gains: 142; Total number of losses: 22; Total Number of normals: 324.
Somatic mutations of THSD7A:
Generating mutation plots.
Highly correlated genes for THSD7A:
Showing top 20/744 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| THSD7A | CYYR1 | 0.795794 | 6 | 0 | 6 |
| THSD7A | C11orf68 | 0.788042 | 3 | 0 | 3 |
| THSD7A | TRPM6 | 0.770844 | 3 | 0 | 3 |
| THSD7A | EBF1 | 0.765131 | 5 | 0 | 5 |
| THSD7A | GIMAP5 | 0.759397 | 3 | 0 | 3 |
| THSD7A | TNFSF12 | 0.75339 | 3 | 0 | 3 |
| THSD7A | TEK | 0.747915 | 8 | 0 | 8 |
| THSD7A | SEC31B | 0.740946 | 3 | 0 | 3 |
| THSD7A | CYGB | 0.735946 | 3 | 0 | 3 |
| THSD7A | CPLX1 | 0.73361 | 3 | 0 | 3 |
| THSD7A | PDK2 | 0.727541 | 3 | 0 | 3 |
| THSD7A | EBF3 | 0.725486 | 5 | 0 | 4 |
| THSD7A | MMRN2 | 0.724245 | 6 | 0 | 6 |
| THSD7A | ABHD1 | 0.721659 | 3 | 0 | 3 |
| THSD7A | GRK5 | 0.721195 | 4 | 0 | 4 |
| THSD7A | CNRIP1 | 0.721126 | 6 | 0 | 6 |
| THSD7A | XPNPEP2 | 0.718295 | 5 | 0 | 5 |
| THSD7A | ARHGAP15 | 0.717225 | 3 | 0 | 3 |
| THSD7A | LRFN5 | 0.715268 | 4 | 0 | 4 |
| THSD7A | TCEAL6 | 0.715002 | 3 | 0 | 3 |
For details and further investigation, click here
