| Full name: pyridine nucleotide-disulphide oxidoreductase domain 2 | Alias Symbol: FLJ23849 | ||
| Type: protein-coding gene | Cytoband: 10q24.2 | ||
| Entrez ID: 84795 | HGNC ID: HGNC:23517 | Ensembl Gene: ENSG00000119943 | OMIM ID: 617889 |
| Drug and gene relationship at DGIdb | |||
Expression of PYROXD2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PYROXD2 | 84795 | 228384_s_at | -0.3173 | 0.6880 | |
| GSE26886 | PYROXD2 | 84795 | 228384_s_at | 0.4300 | 0.0203 | |
| GSE45670 | PYROXD2 | 84795 | 232942_at | 0.1482 | 0.1121 | |
| GSE53622 | PYROXD2 | 84795 | 90336 | -0.0394 | 0.8095 | |
| GSE53624 | PYROXD2 | 84795 | 52069 | -0.0854 | 0.5501 | |
| GSE63941 | PYROXD2 | 84795 | 228384_s_at | -0.5749 | 0.4254 | |
| GSE77861 | PYROXD2 | 84795 | 228384_s_at | -0.0213 | 0.9291 | |
| GSE97050 | PYROXD2 | 84795 | A_23_P24157 | 0.0664 | 0.8432 | |
| SRP064894 | PYROXD2 | 84795 | RNAseq | 0.0196 | 0.9472 | |
| SRP133303 | PYROXD2 | 84795 | RNAseq | -0.3011 | 0.2420 | |
| SRP159526 | PYROXD2 | 84795 | RNAseq | 0.0735 | 0.9074 | |
| SRP193095 | PYROXD2 | 84795 | RNAseq | 0.4274 | 0.0843 | |
| SRP219564 | PYROXD2 | 84795 | RNAseq | 0.3187 | 0.5964 | |
| TCGA | PYROXD2 | 84795 | RNAseq | -0.5637 | 0.0392 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PYROXD2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PYROXD2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PYROXD2 | 84795 | 1 | 8 | 21 | |
| GSE20123 | PYROXD2 | 84795 | 1 | 7 | 22 | |
| GSE43470 | PYROXD2 | 84795 | 0 | 7 | 36 | |
| GSE46452 | PYROXD2 | 84795 | 0 | 11 | 48 | |
| GSE47630 | PYROXD2 | 84795 | 2 | 14 | 24 | |
| GSE54993 | PYROXD2 | 84795 | 8 | 0 | 62 | |
| GSE54994 | PYROXD2 | 84795 | 2 | 11 | 40 | |
| GSE60625 | PYROXD2 | 84795 | 0 | 0 | 11 | |
| GSE74703 | PYROXD2 | 84795 | 0 | 5 | 31 | |
| GSE74704 | PYROXD2 | 84795 | 0 | 4 | 16 | |
| TCGA | PYROXD2 | 84795 | 5 | 28 | 63 |
Total number of gains: 19; Total number of losses: 95; Total Number of normals: 374.
Somatic mutations of PYROXD2:
Generating mutation plots.
Highly correlated genes for PYROXD2:
Showing top 20/165 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PYROXD2 | HDAC9 | 0.759944 | 3 | 0 | 3 |
| PYROXD2 | ITGA7 | 0.742868 | 3 | 0 | 3 |
| PYROXD2 | RAB3A | 0.730482 | 3 | 0 | 3 |
| PYROXD2 | EHD2 | 0.726789 | 3 | 0 | 3 |
| PYROXD2 | SEC31B | 0.718619 | 3 | 0 | 3 |
| PYROXD2 | PAMR1 | 0.710259 | 3 | 0 | 3 |
| PYROXD2 | TECPR2 | 0.701005 | 3 | 0 | 3 |
| PYROXD2 | EBF3 | 0.695704 | 3 | 0 | 3 |
| PYROXD2 | DCHS1 | 0.695503 | 4 | 0 | 4 |
| PYROXD2 | ABCD2 | 0.68897 | 3 | 0 | 3 |
| PYROXD2 | TNS3 | 0.68708 | 3 | 0 | 3 |
| PYROXD2 | STK33 | 0.686446 | 3 | 0 | 3 |
| PYROXD2 | TIMP3 | 0.683213 | 3 | 0 | 3 |
| PYROXD2 | ENO2 | 0.674522 | 3 | 0 | 3 |
| PYROXD2 | TBC1D17 | 0.67045 | 3 | 0 | 3 |
| PYROXD2 | SPRYD3 | 0.669353 | 3 | 0 | 3 |
| PYROXD2 | TPBG | 0.669024 | 3 | 0 | 3 |
| PYROXD2 | NPDC1 | 0.664924 | 3 | 0 | 3 |
| PYROXD2 | CLIC4 | 0.664545 | 3 | 0 | 3 |
| PYROXD2 | BHLHE41 | 0.663427 | 3 | 0 | 3 |
For details and further investigation, click here
