| Full name: cysteine and tyrosine rich 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 21q21.3 | ||
| Entrez ID: 116159 | HGNC ID: HGNC:16274 | Ensembl Gene: ENSG00000166265 | OMIM ID: 616020 |
| Drug and gene relationship at DGIdb | |||
Expression of CYYR1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CYYR1 | 116159 | 228665_at | -0.8183 | 0.1116 | |
| GSE26886 | CYYR1 | 116159 | 228665_at | -1.2290 | 0.0039 | |
| GSE45670 | CYYR1 | 116159 | 228665_at | -1.1847 | 0.0062 | |
| GSE53622 | CYYR1 | 116159 | 56283 | -1.2446 | 0.0000 | |
| GSE53624 | CYYR1 | 116159 | 56283 | -1.0749 | 0.0000 | |
| GSE63941 | CYYR1 | 116159 | 235044_at | 0.3136 | 0.4823 | |
| GSE77861 | CYYR1 | 116159 | 228665_at | -0.1364 | 0.6881 | |
| GSE97050 | CYYR1 | 116159 | A_24_P391230 | -0.7372 | 0.1113 | |
| SRP007169 | CYYR1 | 116159 | RNAseq | 0.6755 | 0.2098 | |
| SRP008496 | CYYR1 | 116159 | RNAseq | 0.7494 | 0.0722 | |
| SRP064894 | CYYR1 | 116159 | RNAseq | 0.1332 | 0.6467 | |
| SRP133303 | CYYR1 | 116159 | RNAseq | -1.0217 | 0.0004 | |
| SRP159526 | CYYR1 | 116159 | RNAseq | 0.1331 | 0.7238 | |
| SRP193095 | CYYR1 | 116159 | RNAseq | -0.2660 | 0.1267 | |
| SRP219564 | CYYR1 | 116159 | RNAseq | -0.5941 | 0.3157 | |
| TCGA | CYYR1 | 116159 | RNAseq | -0.5198 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 5.
Survival by CYYR1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CYYR1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CYYR1 | 116159 | 2 | 11 | 17 | |
| GSE20123 | CYYR1 | 116159 | 2 | 11 | 17 | |
| GSE43470 | CYYR1 | 116159 | 1 | 8 | 34 | |
| GSE46452 | CYYR1 | 116159 | 1 | 21 | 37 | |
| GSE47630 | CYYR1 | 116159 | 6 | 17 | 17 | |
| GSE54993 | CYYR1 | 116159 | 9 | 2 | 59 | |
| GSE54994 | CYYR1 | 116159 | 2 | 8 | 43 | |
| GSE60625 | CYYR1 | 116159 | 0 | 0 | 11 | |
| GSE74703 | CYYR1 | 116159 | 1 | 6 | 29 | |
| GSE74704 | CYYR1 | 116159 | 2 | 7 | 11 | |
| TCGA | CYYR1 | 116159 | 8 | 38 | 50 |
Total number of gains: 34; Total number of losses: 129; Total Number of normals: 325.
Somatic mutations of CYYR1:
Generating mutation plots.
Highly correlated genes for CYYR1:
Showing top 20/1009 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CYYR1 | PREX2 | 0.846301 | 4 | 0 | 4 |
| CYYR1 | BEGAIN | 0.841914 | 3 | 0 | 3 |
| CYYR1 | CYP4V2 | 0.840392 | 3 | 0 | 3 |
| CYYR1 | C15orf41 | 0.818147 | 3 | 0 | 3 |
| CYYR1 | GIMAP5 | 0.806848 | 3 | 0 | 3 |
| CYYR1 | FAM13C | 0.80678 | 4 | 0 | 4 |
| CYYR1 | THSD7A | 0.795794 | 6 | 0 | 6 |
| CYYR1 | SLC16A4 | 0.793769 | 5 | 0 | 5 |
| CYYR1 | CLEC3B | 0.78908 | 3 | 0 | 3 |
| CYYR1 | CAPZA2 | 0.788843 | 4 | 0 | 4 |
| CYYR1 | N4BP2L2 | 0.779338 | 3 | 0 | 3 |
| CYYR1 | EBF3 | 0.77817 | 5 | 0 | 5 |
| CYYR1 | FHL5 | 0.776943 | 5 | 0 | 5 |
| CYYR1 | RHOJ | 0.774303 | 4 | 0 | 4 |
| CYYR1 | TCF21 | 0.77019 | 5 | 0 | 5 |
| CYYR1 | TPSD1 | 0.770129 | 4 | 0 | 4 |
| CYYR1 | TMEM167B | 0.762507 | 4 | 0 | 4 |
| CYYR1 | PCDH18 | 0.755917 | 5 | 0 | 4 |
| CYYR1 | ROR1 | 0.754929 | 5 | 0 | 5 |
| CYYR1 | PRKCA | 0.754292 | 3 | 0 | 3 |
For details and further investigation, click here
