| Full name: zinc finger FYVE-type containing 9 | Alias Symbol: SMADIP|SARA|PPP1R173 | ||
| Type: protein-coding gene | Cytoband: 1p32.3 | ||
| Entrez ID: 9372 | HGNC ID: HGNC:6775 | Ensembl Gene: ENSG00000157077 | OMIM ID: 603755 |
| Drug and gene relationship at DGIdb | |||
ZFYVE9 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04350 | TGF-beta signaling pathway |
Expression of ZFYVE9:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZFYVE9 | 9372 | 204893_s_at | -0.0196 | 0.9696 | |
| GSE20347 | ZFYVE9 | 9372 | 204893_s_at | -0.0694 | 0.3948 | |
| GSE23400 | ZFYVE9 | 9372 | 204893_s_at | -0.0573 | 0.3078 | |
| GSE26886 | ZFYVE9 | 9372 | 204893_s_at | 0.5960 | 0.0003 | |
| GSE29001 | ZFYVE9 | 9372 | 204893_s_at | -0.2156 | 0.3642 | |
| GSE38129 | ZFYVE9 | 9372 | 204893_s_at | -0.1422 | 0.2989 | |
| GSE45670 | ZFYVE9 | 9372 | 204893_s_at | -0.0755 | 0.5508 | |
| GSE63941 | ZFYVE9 | 9372 | 204893_s_at | 0.1881 | 0.5130 | |
| GSE77861 | ZFYVE9 | 9372 | 204893_s_at | -0.0611 | 0.7061 | |
| GSE97050 | ZFYVE9 | 9372 | A_23_P251974 | -0.3627 | 0.1659 | |
| SRP007169 | ZFYVE9 | 9372 | RNAseq | -0.0952 | 0.8250 | |
| SRP008496 | ZFYVE9 | 9372 | RNAseq | 0.1091 | 0.7019 | |
| SRP064894 | ZFYVE9 | 9372 | RNAseq | -0.4227 | 0.0430 | |
| SRP133303 | ZFYVE9 | 9372 | RNAseq | 0.0380 | 0.7875 | |
| SRP159526 | ZFYVE9 | 9372 | RNAseq | 0.3318 | 0.1822 | |
| SRP193095 | ZFYVE9 | 9372 | RNAseq | 0.0332 | 0.7604 | |
| SRP219564 | ZFYVE9 | 9372 | RNAseq | -0.1550 | 0.6161 | |
| TCGA | ZFYVE9 | 9372 | RNAseq | -0.0944 | 0.0692 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ZFYVE9 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of ZFYVE9:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZFYVE9 | 9372 | 3 | 4 | 23 | |
| GSE20123 | ZFYVE9 | 9372 | 3 | 3 | 24 | |
| GSE43470 | ZFYVE9 | 9372 | 5 | 4 | 34 | |
| GSE46452 | ZFYVE9 | 9372 | 2 | 1 | 56 | |
| GSE47630 | ZFYVE9 | 9372 | 8 | 4 | 28 | |
| GSE54993 | ZFYVE9 | 9372 | 0 | 1 | 69 | |
| GSE54994 | ZFYVE9 | 9372 | 11 | 2 | 40 | |
| GSE60625 | ZFYVE9 | 9372 | 0 | 0 | 11 | |
| GSE74703 | ZFYVE9 | 9372 | 4 | 2 | 30 | |
| GSE74704 | ZFYVE9 | 9372 | 2 | 0 | 18 | |
| TCGA | ZFYVE9 | 9372 | 10 | 18 | 68 |
Total number of gains: 48; Total number of losses: 39; Total Number of normals: 401.
Somatic mutations of ZFYVE9:
Generating mutation plots.
Highly correlated genes for ZFYVE9:
Showing top 20/291 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZFYVE9 | TACC2 | 0.796979 | 3 | 0 | 3 |
| ZFYVE9 | WHAMM | 0.781247 | 3 | 0 | 3 |
| ZFYVE9 | RAB3A | 0.780399 | 3 | 0 | 3 |
| ZFYVE9 | ZNF558 | 0.771237 | 3 | 0 | 3 |
| ZFYVE9 | SYMPK | 0.770327 | 3 | 0 | 3 |
| ZFYVE9 | E4F1 | 0.763547 | 3 | 0 | 3 |
| ZFYVE9 | MZF1 | 0.762848 | 3 | 0 | 3 |
| ZFYVE9 | CLIP3 | 0.76202 | 3 | 0 | 3 |
| ZFYVE9 | PLCD3 | 0.757188 | 3 | 0 | 3 |
| ZFYVE9 | ZNF213 | 0.753845 | 3 | 0 | 3 |
| ZFYVE9 | ST6GALNAC6 | 0.745988 | 3 | 0 | 3 |
| ZFYVE9 | KPNA4 | 0.742251 | 3 | 0 | 3 |
| ZFYVE9 | QTRT1 | 0.735335 | 3 | 0 | 3 |
| ZFYVE9 | ADAMTS10 | 0.73426 | 3 | 0 | 3 |
| ZFYVE9 | HSPG2 | 0.726847 | 3 | 0 | 3 |
| ZFYVE9 | RILPL1 | 0.726474 | 3 | 0 | 3 |
| ZFYVE9 | LSM10 | 0.725047 | 3 | 0 | 3 |
| ZFYVE9 | RAD23A | 0.723595 | 3 | 0 | 3 |
| ZFYVE9 | MFHAS1 | 0.722196 | 3 | 0 | 3 |
| ZFYVE9 | PHF2 | 0.718976 | 3 | 0 | 3 |
For details and further investigation, click here
