| Full name: zinc finger DHHC-type containing 11 | Alias Symbol: ZNF399|FLJ13153 | ||
| Type: protein-coding gene | Cytoband: 5p15.33 | ||
| Entrez ID: 79844 | HGNC ID: HGNC:19158 | Ensembl Gene: ENSG00000188818 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of ZDHHC11:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZDHHC11 | 79844 | 232417_x_at | -0.2633 | 0.4462 | |
| GSE26886 | ZDHHC11 | 79844 | 232417_x_at | 0.0704 | 0.8398 | |
| GSE45670 | ZDHHC11 | 79844 | 232417_x_at | 0.1235 | 0.7636 | |
| GSE53622 | ZDHHC11 | 79844 | 34582 | -1.0260 | 0.0000 | |
| GSE53624 | ZDHHC11 | 79844 | 34582 | -1.3304 | 0.0000 | |
| GSE63941 | ZDHHC11 | 79844 | 232417_x_at | 0.8791 | 0.0343 | |
| GSE77861 | ZDHHC11 | 79844 | 232417_x_at | 0.4359 | 0.0435 | |
| GSE97050 | ZDHHC11 | 79844 | A_33_P3344204 | -0.8347 | 0.2370 | |
| SRP133303 | ZDHHC11 | 79844 | RNAseq | -1.1202 | 0.0364 | |
| SRP159526 | ZDHHC11 | 79844 | RNAseq | 0.1802 | 0.8004 | |
| SRP193095 | ZDHHC11 | 79844 | RNAseq | 0.6881 | 0.0401 | |
| SRP219564 | ZDHHC11 | 79844 | RNAseq | -0.1260 | 0.8644 | |
| TCGA | ZDHHC11 | 79844 | RNAseq | -0.3525 | 0.1923 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by ZDHHC11 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZDHHC11:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZDHHC11 | 79844 | 13 | 1 | 16 | |
| GSE20123 | ZDHHC11 | 79844 | 13 | 1 | 16 | |
| GSE43470 | ZDHHC11 | 79844 | 17 | 1 | 25 | |
| GSE46452 | ZDHHC11 | 79844 | 6 | 22 | 31 | |
| GSE47630 | ZDHHC11 | 79844 | 11 | 10 | 19 | |
| GSE54993 | ZDHHC11 | 79844 | 5 | 6 | 59 | |
| GSE54994 | ZDHHC11 | 79844 | 29 | 1 | 23 | |
| GSE60625 | ZDHHC11 | 79844 | 0 | 0 | 11 | |
| GSE74703 | ZDHHC11 | 79844 | 14 | 0 | 22 | |
| GSE74704 | ZDHHC11 | 79844 | 11 | 0 | 9 | |
| TCGA | ZDHHC11 | 79844 | 60 | 4 | 32 |
Total number of gains: 179; Total number of losses: 46; Total Number of normals: 263.
Somatic mutations of ZDHHC11:
Generating mutation plots.
Highly correlated genes for ZDHHC11:
Showing top 20/75 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZDHHC11 | SEC31B | 0.703659 | 3 | 0 | 3 |
| ZDHHC11 | CABIN1 | 0.686594 | 3 | 0 | 3 |
| ZDHHC11 | RALGPS1 | 0.684782 | 5 | 0 | 5 |
| ZDHHC11 | ZNF24 | 0.665352 | 3 | 0 | 3 |
| ZDHHC11 | ADNP2 | 0.663235 | 3 | 0 | 3 |
| ZDHHC11 | TBL1X | 0.650645 | 3 | 0 | 3 |
| ZDHHC11 | R3HDM2 | 0.649383 | 3 | 0 | 3 |
| ZDHHC11 | SORL1 | 0.643805 | 4 | 0 | 3 |
| ZDHHC11 | ZNF397 | 0.637454 | 3 | 0 | 3 |
| ZDHHC11 | SUGP2 | 0.634697 | 4 | 0 | 3 |
| ZDHHC11 | B3GAT2 | 0.63087 | 3 | 0 | 3 |
| ZDHHC11 | DDIT3 | 0.627931 | 3 | 0 | 3 |
| ZDHHC11 | NXF1 | 0.625774 | 3 | 0 | 3 |
| ZDHHC11 | KDM5A | 0.622447 | 3 | 0 | 3 |
| ZDHHC11 | FRMD3 | 0.619814 | 4 | 0 | 3 |
| ZDHHC11 | FKBP8 | 0.617321 | 3 | 0 | 3 |
| ZDHHC11 | ABI2 | 0.614919 | 3 | 0 | 3 |
| ZDHHC11 | PI4KA | 0.614832 | 3 | 0 | 3 |
| ZDHHC11 | INPP5E | 0.61243 | 4 | 0 | 3 |
| ZDHHC11 | ARGLU1 | 0.608181 | 4 | 0 | 3 |
For details and further investigation, click here
