| Full name: striatin 4 | Alias Symbol: ZIN|PPP2R6C | ||
| Type: protein-coding gene | Cytoband: 19q13.32 | ||
| Entrez ID: 29888 | HGNC ID: HGNC:15721 | Ensembl Gene: ENSG00000090372 | OMIM ID: 614767 |
| Drug and gene relationship at DGIdb | |||
Expression of STRN4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | STRN4 | 29888 | 217903_at | 0.5023 | 0.2952 | |
| GSE20347 | STRN4 | 29888 | 217903_at | -0.2417 | 0.0547 | |
| GSE23400 | STRN4 | 29888 | 217903_at | 0.0555 | 0.4178 | |
| GSE26886 | STRN4 | 29888 | 217903_at | 0.3007 | 0.0705 | |
| GSE29001 | STRN4 | 29888 | 217903_at | -0.0125 | 0.9727 | |
| GSE38129 | STRN4 | 29888 | 217903_at | -0.0835 | 0.3628 | |
| GSE45670 | STRN4 | 29888 | 217903_at | -0.0079 | 0.9517 | |
| GSE53622 | STRN4 | 29888 | 129591 | -0.1431 | 0.0104 | |
| GSE53624 | STRN4 | 29888 | 129591 | 0.0198 | 0.7171 | |
| GSE63941 | STRN4 | 29888 | 217903_at | 0.9969 | 0.0033 | |
| GSE77861 | STRN4 | 29888 | 217903_at | 0.1525 | 0.6012 | |
| GSE97050 | STRN4 | 29888 | A_23_P67399 | 0.1513 | 0.5808 | |
| SRP007169 | STRN4 | 29888 | RNAseq | -0.0964 | 0.8131 | |
| SRP008496 | STRN4 | 29888 | RNAseq | 0.0252 | 0.9341 | |
| SRP064894 | STRN4 | 29888 | RNAseq | 0.1426 | 0.3668 | |
| SRP133303 | STRN4 | 29888 | RNAseq | -0.0001 | 0.9997 | |
| SRP159526 | STRN4 | 29888 | RNAseq | 0.2457 | 0.2933 | |
| SRP193095 | STRN4 | 29888 | RNAseq | 0.1572 | 0.1323 | |
| SRP219564 | STRN4 | 29888 | RNAseq | -0.1295 | 0.5234 | |
| TCGA | STRN4 | 29888 | RNAseq | 0.0286 | 0.5047 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by STRN4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of STRN4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | STRN4 | 29888 | 4 | 4 | 22 | |
| GSE20123 | STRN4 | 29888 | 4 | 3 | 23 | |
| GSE43470 | STRN4 | 29888 | 3 | 11 | 29 | |
| GSE46452 | STRN4 | 29888 | 45 | 1 | 13 | |
| GSE47630 | STRN4 | 29888 | 8 | 7 | 25 | |
| GSE54993 | STRN4 | 29888 | 17 | 4 | 49 | |
| GSE54994 | STRN4 | 29888 | 5 | 13 | 35 | |
| GSE60625 | STRN4 | 29888 | 9 | 0 | 2 | |
| GSE74703 | STRN4 | 29888 | 3 | 7 | 26 | |
| GSE74704 | STRN4 | 29888 | 4 | 1 | 15 | |
| TCGA | STRN4 | 29888 | 16 | 16 | 64 |
Total number of gains: 118; Total number of losses: 67; Total Number of normals: 303.
Somatic mutations of STRN4:
Generating mutation plots.
Highly correlated genes for STRN4:
Showing top 20/518 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| STRN4 | AKAP8L | 0.804008 | 3 | 0 | 3 |
| STRN4 | SENP5 | 0.77086 | 3 | 0 | 3 |
| STRN4 | DHX36 | 0.768695 | 3 | 0 | 3 |
| STRN4 | PACS1 | 0.765679 | 4 | 0 | 4 |
| STRN4 | ZNF584 | 0.758738 | 3 | 0 | 3 |
| STRN4 | NUCKS1 | 0.751838 | 3 | 0 | 3 |
| STRN4 | NUDT19 | 0.747211 | 3 | 0 | 3 |
| STRN4 | POLR1C | 0.74538 | 3 | 0 | 3 |
| STRN4 | PWP1 | 0.738035 | 3 | 0 | 3 |
| STRN4 | NRGN | 0.724195 | 3 | 0 | 3 |
| STRN4 | SYNE2 | 0.723894 | 3 | 0 | 3 |
| STRN4 | MED1 | 0.723075 | 3 | 0 | 3 |
| STRN4 | MADD | 0.721471 | 4 | 0 | 4 |
| STRN4 | EEFSEC | 0.72065 | 3 | 0 | 3 |
| STRN4 | NUDT4 | 0.719826 | 3 | 0 | 3 |
| STRN4 | ZNF362 | 0.71931 | 4 | 0 | 4 |
| STRN4 | PLEKHH1 | 0.718894 | 3 | 0 | 3 |
| STRN4 | SEC61A1 | 0.718263 | 3 | 0 | 3 |
| STRN4 | TTF1 | 0.715343 | 3 | 0 | 3 |
| STRN4 | PLCB2 | 0.714329 | 3 | 0 | 3 |
For details and further investigation, click here
